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Understanding of blockchain-based identity management system adoption in the public sector
No full textPurpose
This study aims to understand the benefits and challenges associated with the adoption of a blockchain-based identity management system in public services by conducting an academic literature review, and to explore the design of such a system that can be applied to the Korean government.
Design/methodology/approach
This study explores the adoption of a blockchain-based identity management system using a literature review and an actual design case intended for use by the government sector.
Findings
Blockchain-based identity management systems can significantly improve transparency, accountability, and reliability in the user control of one's own data while reducing the time and cost needed to deliver public services, as well as increasing administrative efficiency. However, it is not always easy to implement such systems, and introducing new technologies in the government field requires a complicated, time-consuming process. There is currently an appetite for research extending beyond the typical technology-driven approach to elucidate the government adoption of new technologies and explore its implications.
Practical implications
The idea behind this system is that by storing and managing personal information on the blockchain and providing mobile apps to customers, users can log in or retrieve previously authenticated personal information without having to go through an authentication process. Since users do not need to go through the verification process every time, it is expected that they will be able to access only the necessary personal information more quickly and conveniently without having to deal with unnecessary details. In addition, the blockchain-based operation of a public service effectively increases the transparency and reliability of that service and reduces the social costs caused by personal information leakage.
Originality/value
This study introduces the design of a blockchain-based identity management system that can be used in public services, specifically in the Korean government sector for the first time. Along with a literature review, the implications that this study gleans from these real-world use cases can contribute to this field of research
Discrete component prognosis for hybrid systems under intermittent faults
No full textPrognosis of discrete component with intermittent fault in hybrid systems is challenging since the component has only two states (i.e., ON and OFF) and no associated physical parameter in the model can quantify the degradation. This article aims to solve the discrete component prognosis problem under the model-based paradigm. First, the fault detection and isolation module help find the possible faulty discrete components. Based on the isolated possible faulty discrete components, Levy flight biogeography-based optimization is proposed to identify the faulty discrete component states, as well as the fault appearing and fault disappearing instants. Second, a Weibull function-based degradation model which can capture the duration evolution of intermittent fault of discrete component in observation window (OW) is developed using coordinate reconstruction approach, and the degradation model coefficients can be calculated from the fault identification results. After that, the concept of failure threshold for faulty discrete component is defined based on the ratio of fault duration to OW, which enables the prognosis of intermittent fault in discrete component. Finally, the proposed methodologies are validated by experiment results. Note to Practitioners —This article is motivated by the intermittent fault prognosis problem of discrete components (e.g., relays and hydraulic valves) in hybrid systems. Existing fault prognosis researches do not consider discrete component which is an important part of hybrid systems. For the intermittent fault prognosis of discrete component, the observation window (OW) concept and coordinate reconstruction (CR) method are proposed to establish the degradation model, and the ratio of fault duration to OW is used to define the failure threshold of discrete component. To show the effectiveness of the proposed methods, an application on a hybrid circuit system is considered. It is noted that the degradation pattern (e.g., increase of frequency or duration of intermittent fault) of discrete components may vary in different systems, while the degradation process can be quantified by the OW and CR methods developed in this article, which enables the prognosis of intermittent fault in discrete component for various hybrid industrial systems. The proposed approach can be applied to industrial hybrid systems if the following conditions are satisfied: 1) the hybrid bond graph model of the monitored system can be established, based on which the fault detection and isolation can be implemented and 2) the monitored system contains multiple discrete components suffering from intermittent faults whose appearing and disappearing instants can be identified by certain method
Production of cracker biscuits using high-protein Australian Noodle Wheat (ANW)
No full textAustralian Noodle Wheat (ANW) is soft-grained wheat primarily grown to suit the production of Japanese udon noodles. ANW with grain protein content above 11.5% (11% m.b.) is classed as ANW2 and traded at a discounted price due to no specific end-use. This study hypothesizes that off-graded ANW2 is suitable to produce cracker biscuits. Evaluation of ANW with 9.7–15.0% protein content shows that those above 11.5% make crackers with higher stack height and lower checking rates. ANW extensibility (r = 0.5, p < 0.05) and development time (r = 0.7, p < 0.01) correlate positively with stack height. The raw dough weight correlates negatively with checking (r = −0.8, p < 0.001), but positively with glutenin (r = 0.5, p < 0.05), α/β-gliadins (r = 0.6, p < 0.05), maximum resistance (r = 0.6, p < 0.05) and development time (r = 0.6, p < 0.01). The α/β-gliadins, maximum resistance and development time correlate negatively (r = 0.5, p < 0.05) with checking. The cracker qualities are not related to glutenin to gliadin ratio, proportions of ω- and γ-gliadins and unextractable polymeric protein. ANW with high protein content contributes to the high extensibility with adequate dough strength required to achieve good cracker stack height while favorably lowering checking rates. ANW2 containing 12–13.0% protein content is ideal for cracker making. This study shows the advantage of applying downgraded ANW in crackers; this may increase its value and benefit the farming industry and biscuit manufacturers
The impact of different crop rotations by weed management strategies’ interactions on weed infestation and productivity of wheat (Triticum aestivum L.)
Get PDFWeed infestations significantly reduce the growth and yield of field crops. Herbicides are mostly used for weed management due to their quick results. However, resistant biotypes to available herbicides are rapidly increasing around the word. This situation calls for the development of alternative weed management strategies. Crop rotation and allelopathic water extracts are regarded as the most important alternative weed management strategies. Therefore, this two-year study assessed the impact of different annual crop rotations by weed management strategies’ interactions on weed infestation and productivity of wheat crop. Wheat was planted in five rotations, i.e., (i) fallow-wheat, (ii) rice-wheat, (iii) cotton-wheat, (iv) mungbean-wheat and (v) sorghum-wheat. The weed management strategies included in the study were; (i) false seedbed, (ii) application of 12 L ha−1 allelopathic plant water extracts (1:1:1:1 ratio of sorghum, sunflower, mulberry and eucalyptus), (iii) herbicide application, (iv) weed-free (weed control) and (v) weedy-check (no weed control). Herbicide application was the most effective treatment in lowering weed densities and biomass during both years followed by false seedbed, while allelopathic crop water extracts were least effective. The lowest weed infestation was noted in sorghum-wheat rotation followed by cotton-wheat and mungbean-wheat, while fallow-wheat had the highest weed infestation. Weedy-check treatment caused significant reduction in wheat growth and yield, whereas the highest grain yield was recorded from weed-free and herbicide application treatments. Grain yield of wheat planted after sorghum was suppressed; however, yield improved when wheat was planted after mungbean. Planting wheat after mungbean in a weed-free environment, achieved through chemical and/or mechanical means, is the best strategy to obtain higher wheat yields
The South African perennial legume Lebeckia ambigua sustainably supports livestock production on infertile soils in rain-fed agro-ecosystems
No full textLebeckia ambigua is a perennial legume endemic to rangeland South Africa that is adapted to dry (< 400-mm annual rainfall), infertile and acidic (below pH 5.5Ca) soils. Although it is considered that the legume was grazed by mammalian ungulates during its evolution, little is known about its production, nutritive value for grazing animals or optimal management in an agricultural context, in either its centre of the origin or in Australia. Experiments were conducted to test the hypotheses that sheep would graze L. ambigua in autumn without adverse effects on either the animal or the plant. Lebeckia ambigua was established at two sites in Western Australia. In experiment 1, three grazing intensities were imposed by exclusion cages introduced during a single intensive grazing period, to provide differing residual pasture heights. The metabolisable energy and crude protein content of L. ambigua were more than 11.4 MJ/kg dry matter and 21%, respectively for all treatments. Un-grazed L. ambigua produced 1740 kg DM/ha while a single moderate or severe grazing reduced total biomass production by about 50% over 10 weeks post-grazing (P < 0.001). In experiment 2, continuous grazing of L. ambigua for 64 days had no negative impacts on biochemical health indicators of merino wethers. Grazing had no effect on plant density in either experiment indicating that L. ambigua is adapted to substantial grazing pressure in autumn. Lebeckia ambigua could become a valuable plant for sustainably increasing livestock production on infertile soils in rain-fed agro-ecosystems where other legumes fail
Polyglutamine ataxias: Our current molecular understanding and what the future holds for antisense therapies
Get PDFPolyglutamine (polyQ) ataxias are a heterogenous group of neurological disorders all caused by an expanded CAG trinucleotide repeat located in the coding region of each unique causative gene. To date, polyQ ataxias encompass six disorders: spinocerebellar ataxia types 1, 2, 3, 6, 7, and 17 and account for a larger group of disorders simply known as polyglutamine disorders, which also includes Huntington’s disease. These diseases are typically characterised by progressive ataxia, speech and swallowing difficulties, lack of coordination and gait, and are unfortunately fatal in nature, with the exception of SCA6. All the polyQ spinocerebellar ataxias have a hallmark feature of neuronal aggregations and share many common pathogenic mechanisms, such as mitochondrial dysfunction, impaired proteasomal function, and autophagy impairment. Currently, therapeutic options are limited, with no available treatments that slow or halt disease progression. Here, we discuss the common molecular and clinical presentations of polyQ spinocerebellar ataxias. We will also discuss the promising antisense oligonucleotide therapeutics being developed as treatments for these devastating diseases. With recent advancements and therapeutic approvals of various antisense therapies, it is envisioned that some of the studies reviewed may progress into clinical trials and beyond
The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function
Get PDFThe LIM-domain containing protein Ajuba and the scaffold protein SQSTM1/p62 regulate signalling of NF-κB, a transcription factor involved in osteoclast differentiation and survival. The ubiquitin-associated domain of SQSTM1/p62 is frequently mutated in patients with Paget’s disease of bone. Here, we report that Ajuba activates NF-κB activity in HEK293 cells, and that co-expression with SQSTM1/p62 inhibits this activation in an UBA domain-dependent manner. SQSTM1/p62 regulates proteins by targeting them to the ubiquitin-proteasome system or the autophagy-lysosome pathway. We show that Ajuba is degraded by autophagy, however co-expression with SQSTM1/p62 (wild type or UBA-deficient) protects Ajuba levels both in cells undergoing autophagy and those exposed to proteasomal stress. Additionally, in unstressed cells co-expression of SQSTM1/p62 reduces the amount of Ajuba present in the nucleus. SQSTM1/p62 with an intact ubiquitin-associated domain forms holding complexes with Ajuba that are not destined for degradation yet inhibit signalling. Thus, in situations with altered levels and localization of SQSTM1/p62 expression, such as osteoclasts in Paget’s disease of bone and various cancers, SQSTM1/p62 may compartmentalize Ajuba and thereby impact its cellular functions and disease pathogenesis. In Paget’s, ubiquitin-associated domain mutations may lead to increased or prolonged Ajuba-induced NF-κB signalling leading to increased osteoclastogenesis. In cancer, Ajuba expression promotes cell survival. The increased levels of SQSTM1/p62 observed in cancer may enhance Ajuba-mediated cancer cell survival
Cross-Reactivity to mutated viral immune targets can influence CD8+ T cell functionality: An alternative viral adaptation strategy
Get PDFLoss of T cell immunogenicity due to mutations in virally encoded epitopes is a well-described adaptation strategy to limit host anti-viral immunity. Another described, but less understood, adaptation strategy involves the selection of mutations within epitopes that retain immune recognition, suggesting a benefit for the virus despite continued immune pressure (termed non-classical adaptation). To understand this adaptation strategy, we utilized a single cell transcriptomic approach to identify features of the HIV-specific CD8+ T cell responses targeting non-adapted (NAE) and adapted (AE) forms of epitopes containing a non-classical adaptation. T cell receptor (TCR) repertoire and transcriptome were obtained from antigen-specific CD8+ T cells of chronic (n=7) and acute (n=4) HIV-infected subjects identified by either HLA class I tetramers or upregulation of activation markers following peptide stimulation. CD8+ T cells were predominantly dual tetramer+, confirming a large proportion of cross-reactive TCR clonotypes capable of recognizing the NAE and AE form. However, single-reactive CD8+ T cells were identified in acute HIV-infected subjects only, providing the potential for the selection of T cell clones over time. The transcriptomic profile of CD8+ T cells was dependent on the autologous virus: subjects whose virus encoded the NAE form of the epitope (and who transitioned to the AE form at a later timepoint) exhibited an ‘effective’ immune response, as indicated by expression of transcripts associated with polyfunctionality, cytotoxicity and apoptosis (largely driven by the genes GZMB, IFNɣ, CCL3, CCL4 and CCL5). These data suggest that viral adaptation at a single amino acid residue can provide an alternative strategy for viral survival by modulating the transcriptome of CD8+ T cells and potentially selecting for less effective T cell clones from the acute to chronic phase
A spectral modelling approach for fluid flow into a line sink in a confined aquifer
No full textA spectral method is developed to study the steady and unsteady flow of fluid into a line sink from a horizontally confined aquifer, and the results are compared to solutions obtained implementing the finite element package COMSOLTM. The aquifer or drain is considered to be confined below so that the solutions are fundamentally unsteady. Comparison is made between the two methods in determining the drawdown of the surface
Wayfinding: Navigating complexity for sustainable school leadership
No full textSchool leaders navigate a multiplicity of frameworks, roles, and expectations. The destination of school leaders is a complex and moving target, hard to pin down and even harder to set course for due to the complexities of the constantly moving parts of the reality of leading schools. The Australian Professional Standards for Principals reflect the overwhelming expectations placed on school leaders, who must be across global and local issues, curriculum, professional standards, policy, and wellbeing of all in the school community. Principals and senior school leaders constantly code switch between strategising, leading, teaching, administrating, coaching, counselling, complying, mediating, resolving, gatekeeping, resourcing, and negotiating. They are expected to align ethical action with coherent vision, deep understanding of context, and a working knowledge of education research. They are expected to be unwavering in their moral purpose and in the transparency, consistency, and logic of their decision making. As two senior leaders of pedagogy, curriculum, and staff development in schools in Australia, we authors bring to this chapter our lived experiences of school leadership. In addition to our leaderly identities, we explore our simultaneous researcher identities as, post-PhD, we continue to moonlight as researchers, academic writers, and academic readers. We are both also parents of primary school aged children, a role that influences how we approach leading. In this chapter, we explore the metaphor of wayfinding as a lens to theorise how school leaders navigate concurrent and complementary identities to lead with purpose, compassion, knowledge, and intentionality, in ways that are sustainable for themselves and their schools