Institute of Chemistry
Changchun Institute of Applied Chemistry, Chinese Academy Of SciencesNot a member yet
23443 research outputs found
Sort by
稀土纳米亲和材料的设计合成及其对磷酸化肽的富集
No full text作为一种典型的蛋白翻译后修饰方式，蛋白质磷酸化在生物体内广泛存在并扮演着极其关键的角色。蛋白质磷酸化是生物体调控众多生命化学过程所不可或缺的，而且许多疾病与异常的蛋白质磷酸化具有密切的关系，所以，研究蛋白质磷酸化对于生化过程的揭示以及疾病的诊断治疗是极为重要的。在当前的磷酸化蛋白质组学研究中，质谱是最为重要的分析手段，而生物样品的复杂性使得磷酸化肽的质谱鉴定面临极大的困难。因此，磷酸化肽的有效富集分离成为磷酸化蛋白质组学研究中需要首先解决的关键问题。 本论文中，针对磷酸化肽的富集分离和质谱鉴定中的问题，我们成功合成了一系列新型的磁功能化稀土纳米亲和材料，探究了这些亲和材料在磷酸化肽富集中的应用效果，并初步探索了亲和材料的表面结构对亲和材料在磷酸化肽富集应用中的重要影响。首先，通过合理设计合成策略，采用一些通用性强且简单易行的方法（如化学共沉淀法、离子交换法、溶液聚合法等），我们成功合成出多...As a typical post-translational modification, protein phosphorylation exists widely and plays a critical role in living organisms. Protein phosphorylation is indispensable in control and regulation of various biological processes in living organisms, and many diseases have close connections with abnormal protein phosphorylations. Thus, studying protein phosphorylation is very important for revealing biological processes and diagnoses and treatments of diseases. In modern phosphoproteome research, mass spectrometry (MS) is the most important analysis tool. However, the complexities of biosamples seriously hamper the MS analysis of protein phosphorylation. Therefore, the efficient enrichment and isolation of phosphopeptides have become a key problem that firstly needs to be solved in phospho..
支化聚苯乙烯/纳米粒子复合材料的熔体粘度行为研究
No full text在聚合物基体中添加纳米粒子有利于提高聚合物多方面的性能，如：提高机械性能、改善加工过程、提高聚合物的透明性等。而非常重要的一点是加入纳米粒子能较大程度地改善聚合物熔体的流动性，进而改善材料的加工性能。弄清楚纳米粒子添加后复合材料的熔体粘度行为是解决高分子复合材料加工若干问题的突破口。本论文利用可控聚合的方法制备了不同拓扑结构的聚苯乙烯，首次研究了支化聚合物/球形纳米粒子复合材料的熔体粘度行为。主要从苯乙烯的拓扑结构、纳米粒子的种类、纳米粒子尺寸这几个方面开展了系统性的研究工作，总结了关于支化聚苯乙烯熔体粘度调控的方法，并对这其中的可能机理进行了探讨。所取得的具体研究结果如下： 1. 利用阴离子聚合和ATRP聚合法合成了线形聚苯乙烯、三臂星形聚苯乙烯和六臂星形聚苯乙烯，以C60作为模型纳米粒子，研究了聚苯乙烯/C60复合材料的熔体粘度行为。实验结果表明：星形聚苯乙烯（SPS）的单臂分子量（M...The addition of nanoparticles into polymer matrices is expected to improve polymer properties, such as mechanical reinforcement, processing properties and transport properties etc. One of the hot topics is about the influence of added nanoparticles on polymer melt fluid, which is related to the processing properties. Study on the influence of nanoparticle on the melt viscosity behavior of the composites is important for the processing of these composites. Polystyrene (PS), the first synthesized polymer, can be synthesized with many kinds of polymerization method. Controlled polymerization was used to synthesize branched PS in this dissertation. The melt viscosity behavior of branched PS/spherical nanoparticle composites was studied for the first time, especially the influences of topologic..
Facile and Low-Cost Sodium-Doping Method for High-Efficiency Cu2ZnSnSe4 Thin Film Solar Cells
No full textWe present a simple and low-cost sodium-doping method for Cu2ZnSnSe4 (CZTSe) thin film solar cells. In this method, a piece of soda-lime glass (SLG) is served as the sodium source and is placed on top of the CZTSe precursor thin film during selenization. It was observed that the grain growth and the hole-carrier concentration can be significantly improved by the diffusion of sodium from the top SLG. Through this approach, high-quality CZTSe absorber layer is obtained after the selenization, and the photoelectric conversion efficiencies (PCE) of 7.51% and 6.09% are achieved for CZTSe thin film solar cells deposited on a Mo-coated SLG substrate and a Mo-coated quartz substrate, respectively. The difference in PCE on SLG and quartz substrate revealed that Na diffusion from the bottom SLG substrate and the top SLG was most effective for the high-performance of CZTSe solar cell devices
Utilizing 3d-4f Magnetic Interaction to Slow the Magnetic Relaxation of Heterometallic Complexes
No full textThe synthesis, structural characterization, and magnetic properties of four related heterometallic complexes with formulas [(Dy2CoII)-Co-III(C7H5O2)(8)] 6H(2)O (1), [(Dy2NiII)-Ni-III(C7H5O2)(8)] (C7H6O2)(2) (2), (Tb2CoII)-Co-III(C7H5O2)(8) (3), and (Dy2CdII)-Cd-III(C7H5O2)(8) (4) were reported. Each of complexes has a perfectly linear arrangement of the metal ions with two terminal Ln(III) (Ln(III) = Dy-III, Tb-III) ions and one central M-II (M-II = Co-II, Ni-II, Cd-II) ion. It was found that 13 displayed obvious magnetic interactions between the spin carriers according to the direct current (dc) susceptibility measurements. Alternating current (ac) magnetic susceptibility measurements indicate that complexes 1-4 all exhibit single-molecule magnet (SMM) behavior, while the replacement of the diamagnetic CdII by paramagnetic ions leads to a significant slowing of the relaxation thanks to the magnetic interactions between 3d and 4f ions, resulting in higher relaxation barrier for complexes 1 and 2. Moreover, both Dy2Co and Dy2Ni compounds exhibit dual relaxation pathways that may originate from the single ion behavior of individual Dy-III ions and the coupling between Dy-III and Co-II/Ni-II ions, respectively, which can be taken as the feature of 3d-4f SMMs. The U-eff for 1 of 127 K is a relatively high value among the reported 3d-4f SMMs. The results demonstrate that the magnetic coupling between 3d and 4f ions is crucial to optimize SMM parameters. The synthetic approach illustrated in this work represents an efficient route to design nd-4f based SMMs via incorporating suitable paramagnetic 3d and even 4d and 5d ions into the df system
Photoluminescence Properties of Efficient Blue-Emitting Phosphor alpha-Ca1.65Sr0.35SiO4:Ce3+: Color Tuning via the Substitutions of Si by Al/Ga/B
No full textA series of Ce3+-doped alpha-Ca1.65Sr0.35SiO4 (CSSO) phosphors without and with the substitutions of Si by Al/Ga/B were synthesized via the high-temperature solid-state reaction process. X-ray diffraction patterns and Rietveld refinements were used to demonstrate the successful incorporations of Al/Ga/B into CSSO:Ce3+. Without Al/Ga/B, the Ce3+ singly doped CSSO phosphors present intense blue emission, which correspond to the broad emission bands in visible region with the wavelength range from 360 to 580 nm upon 350 nm excitation. The optimal emission intensity occurs in CSSO:0.05Ce(3+) sample with the emission peak wavelength at 436 nm. With the introduction of Al/Ga/B into the CSSO:0.05Ce(3+), the emission peak shifts from 436 to 457/465/446 nm under 365 nm excitation, respectively. The red shift of Ce3+ emission is attributed to the polyhedral distortion of the cations, resulting in the enhancement of crystal field spitting due to the variations of the adjacent (Al/Ga/B,Si)O-4 polyhedron. Moreover, the temperature-dependent photoluminescence was determined to be of light impact to CSSO:Ce3+ with the introduction of Al/Ga/B. This research is useful for enriching the emission colors of Ce3+-activated phosphors
Nanoporous molybdenum carbide nanowires: a novel sensing platform for DNA detection
No full textIn this communication, a novel and highly sensitive DNA sensor based on nanoporous molybdenum carbide nanowires (Mo2C NWs) is presented. The Mo2C NWs were synthesized on a large scale via pyrolysis of a MoOx/amine hybrid precursor under an inert atmosphere. The enriched nanoporosity and the large active surface of these highly dispersed nanowires with uniform Mo2C nanocrystallites make them an efficient nanosensor, leading to their high sensitivity with a detection limit of 50 pM and good selectivity
One-pot synthesis of carbon nanodots for fluorescence turn-on detection of Ag+ based on the Ag+-induced enhancement of fluorescence
No full textCarbon quantum dots (C-dots) are promising fluorescence probes for applications in metal ion detection, biosensing and bioimaging and so on. In this study, water soluble carbon nanodots were synthesized through a simple one-step heat treatment of ethylene glycol solution. In the present preparation, the C-dots may be formed through the hydration, crosslinking and carbonization processes. The synthesized C-dots show a green luminescent emission under ultraviolet excitation, which can be used for the detection of Ag+ ions. Interestingly, in a different way to the usual quenching effects of metal ions on the fluorescence of C-dots, Ag+ exhibited an enhancement effect on the photoluminescence of C-dots, which can be attributed to the reduction of Ag+ to silver nanoclusters (Ag-0) on the surface of the C-dots. Based on the linear relationship between fluorescence intensity and concentration of Ag+ ions, the prepared C-dots can be used for sensitive and selective detection of silver ions in environmental water with a limit of detection of 320 nM and a linear range of 0-90 mu M
A binary solvent mixture-induced aggregation of a carbazole dendrimer host toward enhancing the performance of solution-processed blue electrophosphorescent devices
Full text linkThe emissive layer morphology strongly correlates with the charge transport and light-emitting performance of solution-processed phosphor-doped organic light-emitting diodes (PhOLEDs). Herein, morphology manipulation of the solution-processed emissive layer comprising of carbazole dendrimer (H2) host: blue phosphor (FIrpic) guest is realized via processing of the solvent and its influence on charge transport and light-emitting properties is investigated. The formation of H2 aggregates within its amorphous matrix processed with the toluene: p-xylene solvent mixture distinctively improves the hole and electron transport within the emissive layer, helping to lower the driving voltages and improve the light-emitting efficiency. However, excess aggregation of H2 would result in non-uniform dispersion of the FIrpic guest within the H2 host, leading to non-complete host-to-guest energy transfer and decreased electroluminescence performance. Through manipulation of the aggregates within the H2 host by varying the solvent mixture ratio, the trade off between charge transport and energy transfer is realized. Finally, the solution-processed blue PhOLED with optimized emissive layer morphology processed with toluene : p-xylene (9 : 1) solvent mixture achieves a high light-emitting efficiency of 27.8 cd A(-1), corresponding to 25% enhancement compared to 22.2 cd A(-1) of the control device processed with commonly used toluene solvent
Label-free fluorescence turn-on detection of microRNA based on duplex-specific nuclease and a perylene probe
No full textA novel fluorescence turn-on microRNA (miRNA) detection method based on duplex-specific nuclease (DSN) and a perylene probe is presented in this study. A positively charged perylene derivative (compound 1) was used as the fluorescent probe. Compound 1 exhibits strong monomer fluorescence in an aqueous buffer solution. It is well known that single-stranded DNA is a polyanion in nature. Thus, it can induce the aggregation of compound 1 through strong electrostatic, hydrophobic and pi-pi stacking interactions. As a result, the fluorescence of compound 1 was efficiently quenched. When the target miRNA was added, the formation of DNA-RNA hybridized duplex initiated the cleavage of the DNA strand by DSN cycle reaction, which resulted in disaggregation of compound 1. A fluorescence turn-on signal was detected, and a novel miRNA sensing method was therefore established. The presented method is label-free, simple, cost effective, sensitive and selective. (C) 2015 Elsevier B.V. All rights reserved
Facile Synthesis of 3D Hierarchical Flower-like Co3-xFexO4 ferrite on Nickel Foam as High-Performance Electrodes for Supercapacitors
No full textA facile hydrothermal method combined with a post solution reaction is developed to synthesize interconnected three-dimension (3D) hierarchical Co3-xFexO4 ferrite (CF) on nickel foam. By controlling the experimental parameters, the structures of the products are tailored from nanoflowers to microflowers with different sized void interiors. The obtained 3D hierarchical flower-like CF are characterized by field emission scanning electron microscopy, X-ray diffraction, and inductively coupled plasma mass spectrometer analysis. The 3D hierarchical flower-like CF-nickel foam with the rational structural feature could be used as binder and conductive agent-free supercapacitor electrodes directly. Such integrated electrodes exhibit a high specific capacitance and well cycling stability when the chargedischarge current density is high. Remarkably, the 3D hierarchical CF microflowers exhibit specific capacitance values of 768 F g(-1) at a constant current density of 6 A g(-1). The CF microflowers also show high charge-discharge reversibility with an efficiency of 79.2% after 5000 cycles. (C) 2014 Elsevier Ltd. All rights reserved