Institute of Chemistry
Changchun Institute of Applied Chemistry, Chinese Academy Of SciencesNot a member yet
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Coadministration of Vascular Disrupting Agents and Nanomedicines to Eradicate Tumors from Peripheral and Central Regions
No full textQuantitative synthesis of bis(cyclic carbonate) s by iron catalyst for non-isocyanate polyurethane synthesis
No full textBis(cyclic carbonate) s were quantitatively prepared with high efficiency via the coupling reaction of carbon dioxide (CO2) with diglycidyl ethers by a [ Fe(BPMCDAC)]/TBAB catalytic system, where glycol diglycidyl ether (1a) could be completely converted to the corresponding bis(cyclic carbonate) (2a) with a turnover number of 1000 at 100 degrees C and 3 MPa in 4 h. The obtained bis(cyclic carbonate) (2a) could be used to prepare hydroxyl-functional polyurethanes via reaction with diamines, which may be one alternative for obtaining conventional polyurethanes without the use of toxic phosgene or isocyanates. The number-average molecular weights of the obtained non-isocyanate polyurethanes (NIPUs) were up to 25.4-30.2 kg mol(-1), and the polydispersity indexes (PDIs) were relatively narrow between 1.18 and 1.22. A typical NIPU showed a glass transition temperature of 9 degrees C and an initial degradation temperature (T-d 5%) of 206 degrees C
pH-sensitive OEI-poly(aspartic acid-b-lysine) as charge shielding system for gene delivery
No full textControllable synthesis of cube-like ZnSnO3@TiO2 nanostructures as lithium ion battery anodes
No full textZnSnO3 is an attractive anode material for lithium ion batteries because of its higher theoretical capacity compared to the state-of-the-art carbonaceous counterpart. The main challenges associated with ZnSnO3 anodes are structural degradation and instability of the solid-electrolyte interphase, caused by the large volume change during cycling. Herein, we propose a hierarchical structured ZnSnO3@TiO2 nanocomposite anode that tackles this problem. The as-prepared, core-shell, cube-like anode material exhibits enhanced capacity and cycling property. In proof-of-concept experiments, this hierarchical heterostructure shows a high initial discharge capacity of 1590 mA h g(-1) at 100 mA g(-1) and retained 780 mA h g(-1) after 200 cycles, which is much better than the anodes made of pure ZnSnO3 nanomaterials. The enhanced cycle life can be attributed to the reductive volume expansion during the repeated charge-discharge cycles, owing to the hierarchical porous three-dimensional structure and TiO2 shell as well as the synergistic effects of ZnSnO3 and TiO2
Facile preparation of an ultrathin sulfur-wrapped polyaniline nanofiber composite with a core-shell structure as a high performance cathode material for lithium-sulfur batteries
No full textAn ultrathin sulfur layer (10 nm) wrapped polyaniline (PANI) nanofiber composite (S-PANI) with a core-shell structure was prepared via facile heterogeneous nucleation of sulfur on a water-dispersed PANI nanofiber, which displayed an initial discharge capacity of 977 mA h g(-1) and a capacity retention of 88.3% after 100 cycles at 1 C
Efficiently photocatalytic reduction of carcinogenic contaminant Cr (VI) upon robust AgCl:Ag hollow nanocrystals
No full textHerein, we newly present a robust photocatalyst in terms of AgCl:Ag-Hollow nanocrystals (NCs) which exhibit fast photoreduction rate for representative carcinogenic contaminant (Cr (VI)) into the benign form(10 min). The provided hollow structure significantly enhanced light absorption and specific surface area (42 times than normal AgCl material), which are the two critical factors to improve the photoreduction activity. Further, the Schottky junction of the plasmonic system facilitates separation of photo-induced electrons and holes, which absolutely benefits the photocatalysis reactions. The photocurrent intensity, kinetic responses with apparent kinetic rate constant (kapp) and apparent quantum efficiency (AQE) (within 6 min) of AgCl:Ag-Hollow NCs were about 4-8, 5.3 and 2.7 times as that of normal AgCl material, respectively. Most strikingly, we anticipate such AgCl:Ag-Hollow NCs might become a promising candidate for practical application of water cleansing and environmental pollution purifying under visible light irradiation in the future. (C) 2014 Elsevier BM. All rights reserved
Carbon with ultrahigh capacitance when graphene paper meets K3Fe(CN)(6)
No full textFor the first time, we have shown a novel supercapacitor system with a graphene paper electrode in the redox-electrolyte of K3Fe(CN)(6) based on the system-level design principle. By combining electric double-layer capacitance and pseudocapacitance, the specific capacitance could be increased 5-fold compared with the conventional electrode-electrolyte system. This large improvement is attributed to the additional redox reactions on the graphene paper electrode via the constituent ions of K3Fe(CN)(6) in the redox-electrolyte, during which the discharge process is highly enhanced. More importantly, the potential interval could reach as high as 1.6 V beyond the limited operating voltage of water (similar to 1.23 V). After 5000 continuous cycles, 94% of the initial capacitance was retained. The newly designed novel supercapacitor system is binder-free, conducting additive-free and can deliver higher capacitance. This designed graphene-paper-electrode/redox-electrolyte system can provide a versatile strategy for high-capacitance supercapacitor systems
Revealing the carbohydrate pattern on a cell surface by super-resolution imaging
No full textCarbohydrates are involved in various physiological and pathological activities including cell adhesion, signal transduction and tumor invasion. The distribution of carbohydrates is the molecular basis of their multiple functions, but remains poorly understood. Here, we employed direct stochastic optical reconstruction microscopy (dSTORM) to visualize the pattern of N-acetylglucosamine (N-GlcNAc) on Vero cell membranes at the nanometer level of resolution. We found that N-GlcNAcs exist in irregular clusters on the apical membrane with an average cluster area of about 0.37 mu m(2). Most of these N-GlcNAc clusters are co-localized with lipid rafts by dual-color dSTORM imaging, suggesting that carbohydrates are closely associated with lipid rafts as the functional domains. Our results demonstrate that super-resolution imaging is capable of characterizing the distribution of carbohydrates on the cellular surface at the molecular level
Surfactant-assisted fabrication of 3D Prussian blue-reduced graphene oxide hydrogel as a self-propelling motor for water treatment
No full textThree-dimensional Prussian blue-reduced graphene oxide hydrogel was synthesized with the assistance of sodium dodecyl sulfate (SDS) through a facile hydrothermal method. The hydrogel exhibited strong mechanical properties and was successfully applied as a self-propelling motor for water treatment. During the self-propelling degradation process, SDS facilitated the rapid liberation of oxygen bubbles from the motor and the oxygen bubbles assisted the rapid diffusion of hydroxyl radicals. In addition, the well-defined structure increased the number of reaction sites and the synergy between reduced graphene oxide and Prussian blue, which accelerated the degradation efficiency. The self-propelling motor had an average velocity of 0.026 +/- 0.013 cm s(-1) in 7.5% H2O2 and 0.069 +/- 0.032 cm s(-1) in 22.5% H2O2. Moreover, the self-propelling motor maintained high degradation efficiency even after cycling for 9 times. These excellent properties make the self-propelling motor an ideal candidate for water treatment
A cytotoxic amyloid oligomer self-triggered and NIR-enhanced amyloidosis therapeutic system
No full textWe report a new strategy for improving the efficiency of non-specific amyloidosis therapeutic drugs by coating amyloid-responsive lipid bilayers. The approach had drawn inspiration from amyloid oligomer-mediated cell membrane disruption in the pathogenesis of amyloidosis. A graphene-mesoporous silica hybrid (GMS)-supported lipid bilayer (GMS-Lip) system was used as a drug carrier. Drugs were well confined inside the nanocarrier until encountering amyloid oligomers, which could pierce the lipid bilayer coat and cause drug release. To ensure release efficiency, use of a near-infrared (NIR) laser was also introduced to facilitate drug release, taking advantage of the photothermal effect of GMS and thermal sensitivity of lipid bilayers. To facilitate tracking, fluorescent dyes were co-loaded with drugs within GMS-Lip and the NIR laser was used once the oligomer-triggered release had been signaled. Because of the spatially and temporally controllable property of light, the NIR-assisted release could be easily and selectively activated locally, by tracking the fluorescence signal. Our design is based on amyloidosis pathogenesis, the cytotoxic amyloid oligomer self-triggered release via cell membrane disruption, for the controlled release of drug molecules. The results may shed light on the development of pathogenesis-inspired drug delivery systems