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颠覆性技术识别指标的研究进展
No full text［目的/意义］ 颠覆性技术常以意想不到的方式取代传统技术或主流技术，能够对经济、社会、国家竞争力等产生重大影响。通过分析颠覆性技术的识别指标，为后续识别研究与实践提供参考。［方法/过程］ 立足颠覆性技术的内涵与特征，从技术特征、市场特征、宏观环境等角度分析了现有指标体系，总结了存在的问题并提出意见。［结果/结论］ 颠覆性技术的识别指标大多建立在已有的方法基础上，针对其核心特征的指标设计难度较大，且缺乏量化标准。未来的指标研究应在科学的理论指导下，借助大数据及人工智能技术探索颠覆性技术的内在发展规律，并集成主客观分析方法以及定性定量信息，构建综合性指标体系，增强识别的科学性和精准性。</p
Analysis of ACE2 gene encoding protein in mammalian species
No full textHuman beings are currently experiencing a serious public health event. Novel coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), has infected about 3 million people worldwide and killed more than 200,000, most being the elderly or people with potential chronic diseases or in immunosuppressive states. According to big data analysis, there are many proteins homologous to or interacting with the angiotensin-converting enzyme 2 (ACE2), which, therefore, may not be the only receptor for the novel coronavirus; other receptors may also exist in host cells of different species. These potential receptors may also play an important role in the infection process of the novel coronavirus. The current study aimed to discover such key proteins or receptors and analyze the susceptibility of different animals to the novel coronavirus, in order to reveal the transmission process of the virus in cross-species infection. We analyzed the proteins coded by the ACE2 gene in different mammalian species and predicted their correlation and homology with the human ACE2 receptor. The major finding of our predictive analysis suggested ACE2 gene-encoded proteins to be highly homologous across mammals. Based on their high homology, their possibility of binding the spike-protein of SARS-CoV-2 is quite high and species such as Felis catus, Bos taurus, Rattus norvegicus etc. may be potential susceptible hosts; special monitoring is particularly required for livestock that are in close contact with humans. Our results might provide ideas for the prevention and control of the novel coronavirus pneumonia.</p
机构知识库在科研评价服务中的应用及实现
No full text机构知识库作为科研机构保存和管理知识成果的重要平台，有效地融入科研流程和更好地支撑科研管理是未来的发展趋势，也是当前国内外的研究热点。本文对目前机构知识库科研评价应用现状进行梳理，针对数据来源、数据查重及关联、评价指标及方法、元数据标准及互操作等关键问题进行分析，并基于中国科学院机构知识库CSpace系统进行若干功能的开发和实现。系统的科研评价功能已在多家科研院所及高校应用，取得了较好的服务效果。</p
开放科学环境下数据馆员的实践探析
No full text［目的／意义］开放科学环境下，明确数据馆员的基本内涵、在业务流程中的作用及其职业可持续发展方案，有助于对数据馆员进行岗位设置，并为学术图书馆开展创新服务提供参考借鉴。［研究设计／方法］系统调研国内外数据馆员相关文献，梳理其基本概念、职能作用，分析学术图书馆数据馆员的发展实践与现实需求的匹配情况。根据数据馆员招聘信息，提炼其工作内容，提出可持续发展方案。［结论／发 现］数据馆员能够在开放科学环境下支持科研人员处理数据管理实践与数据治理事宜。学术图书馆以教育培训和促进职业群体自我发展的方式，增加数据馆员的竞争力，提升科研用户满意度。［创新／价值］提炼数据馆员基本研究框架、工作维度模型；提出从数据生产与流转周期角度剖析开放科学环境下科研数据全生命周期，阐明数据馆员在其中的作用。 </div
