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Discovering Candidate Genes in Forest Antelope to Map Adaptive Variation in Africa
No full textThe blue duiker, Philantomba monticola, is one of the most important protein sources across Central Africa, and it is therefore becoming increasingly susceptible to unsustainable hunting as well as climate-induced changes in the distribution of suitable habitat. This project aims to assess adaptive evolutionary potential of this species in order to predict how well it may be able to evolve in response to projected environmental changes across its habitat range. After surveying the available literature, we identified three promising candidate genes that might constitute targets of selection: MC1R, DMBT1 and SCL7A13. Work on other bovids has shown that single nucleotide polymorphisms (SNPs) within these genes are associated with adaptive phenotypic changes linked to either disease resistance (DMBT1, SCL7A13) or coat color differentiation (MCIR). The Bos taurus genome was used to design primers in order to cross-amplify these genes in P. monticola and related artiodactyl species C. callipygus, C. dorsalis, and C. nigrifrons. The resulting amplified fragments encompassing candidate SNPs were sequenced using the BigDye kit (ABI, CA) and aligned in the program MEGA v. 6.0 (Tamura et al. 2013). In all four species, both the MC1R and SLC7A13 gene contained the SNP leading to a nonsynonymous change at the location reported. Interestingly, only the P. monticola individuals had the SNP found within the DMBT1 gene. In addition, an unrecorded nonsynonymous change was present in the DMBT1 and SLC7A13 gene of various individuals. These methods can be replicated for numerous other loci, and the sequences will be used to design primers necessary for constructing a Fluidigm array by which fecal DNA can be genotyped rapidly. Adaptive variation in the P. monticola genome will be identified and mapped across central Africa, and this data will be directly considered in identifying geographic regions of elevated adaptive potential that deserve future protection
The origin and expansion of the eastern red fox
Get PDFWhen new populations are first identified in a region there are multiple potential sources: introduction of a non-native species, extra-range expansion of a nearby population, or demographic growth of a previously unnoticed species. Red foxes were absent or rare in the mid-eastern portion United States until the late 1800s. Their origins potentially include natural population increase/expansion, translocations from Europe, and, eventually, 20th century fur farming. In this study I attempt to identify the relative impact of native expansion versus human mediated introductions of both colonial era European foxes and early 20th century fur-farm foxes on the establishment of red foxes in the mid-Atlantic region of the United States. I subsequently address the potential impacts of hybridization and nuclear introgression between previously separate sister taxa. Through analysis of mitochondrial DNA, I identified indigenous haplotypes, two European haplotypes, and fur-farm haplotypes; another set of haplotypes were potentially indigenous or native. In addition, I found European Y-chromosome haplotypes. Most European and fur-farm haplotypes were found near the densely human-populated coastal plain and Hudson River lowlands; most red foxes of the Appalachians and Piedmont had native eastern haplotypes. However, nuclear data does not support this division showing low genetic structure despite the broad geographic scale of our study area, attributable both to range expansion and admixture. Admixture has not had the same impact on the nuclear genome as it has in mitochondrial haplotypes leading to mito-nuclear discordance across the region. I also found evidence for differential patterns of expansion related to habitat. Specifically, the Appalachian Mountains acted as a corridor for gene flow from the northern native source into the southern Mid-Atlantic regio
The Unmaking of an Embargo: How Policy Entrepreneurs at the Individual, State, and National Levels are Creating New Paths for Policy Change in Modern United States-Cuba Relations
Get PDFThroughout the Cold War antagonisms of the twentieth century, the United States (US) championed greater global economic cooperation and an embrace of free market principles to encourage economic growth. Post World War II, passage of the Bretton Woods Agreement institutionalized this political agenda effectively establishing the rules of global commerce. The result has been increased economic participation and trade liberalization. One of the last remaining vestiges of Cold War hostility and impediments to trade is the US economic embargo of Cuba, in place since 1960. Increasingly seen as a policy failure, the US has taken steps in the past two years to normalize relations with Cuba. At the same time, after extended conflicts in Afghanistan and Iraq, economic recession, and political polarization over the last fifteen years the US finds itself in a position of ambiguity towards additional foreign commitments. American efforts to open Cuba to two-way commerce serve both national security and economic foreign policy agendas. For Cubans, removal of the embargo represents an opportunity for normal relations with the world’s largest economy and access to capital and markets that come with it. The purpose of this study is to test the theory political economy, which attempts to understand society through the intersection of economic, political, and social functions, using US-Cuba diplomacy as a case study (Yin, 2009). Working within a multiple streams framework, the investigator examined how economic policy is changed under politically ambiguous conditions through a series of 20 semi-structured qualitative interviews and content analysis of secondary data sources (Zahariadis, 2014). Specifically, the study explored the behavior of interested individuals from the US and Cuba, so-called policy entrepreneurs, and their influence on the policymaking process during an open policy window. Research results suggest that policy entrepreneurs operate at the individual, state, and national scales of society using a variety of symbols to create and broaden opportunities for policy change. Across all three levels, US and Cuban policy entrepreneur’s behavior is guided by the search for rationality in ambiguous times, but their agency is bounded by the institutionally determined parameters of what is legally and politically acceptable
‘Our Responsibility and Privilege to Fight Freedom’s Fight’: Neoconservatism, the Project for the New American Century, and the Making of the Invasion of Iraq in 2003
Get PDFThe Project for the New American Century (PNAC) was a neoconservative Washington, D.C. foreign policy think tank, comprised of seasoned foreign policy stalwarts who had served multiple presidential administrations as well as outside-the-beltway defense contractors, that was founded in 1997 by William Kristol, editor of the conservative political magazine The Weekly Standard, and Robert Kagan, a foreign policy analyst and political commentator currently at the Brookings Institution. The PNAC would shut down its operations in 2006. Using The Weekly Standard as its mouthpiece, the PNAC helped foment support for the removal of Iraqi president Saddam Hussein beginning in 1998, citing Iraq’s noncooperation with UN weapons inspections. The PNAC became further emboldened in its urgency and rhetoric to quell the geopolitical risk posed by Hussein after the 9/11 terror attacks. The only justifiable response the George W. Bush Administration could play in thwarting Hussein, the PNAC argued, involved a military action.
Keywords: The Project for the New American Century; Iraq War; Saddam Hussein; The Weekly Standard; The Vulcans; weapons of mass destructio
The First Year Transition and Resilience of Precollege Outreach Program Alumni
Get PDFWhile traditionally underrepresented groups are attaining degrees at a higher rate than ever before, these students still receive bachelor’s degrees at significantly lower rates than other groups of students (Avery & Kane, 2004; Wilds, 2000). As a result of the educational attainment gap in the United States, precollege outreach programs have been established to provide resources for underrepresented youth to aid them in completing a post-secondary degree. Current research focuses on these participants’ college enrollment and, as a result, minimal information is available to describe these programs and their outcomes concerning students’ first year experience and college success (Hooker & Brand, 2009; Orr et al., 2007; Swail & Perna, 2002; Yeung, 2010). Framed around resiliency theory, this phenomenological study exams college access program alumni’s acclimation process into a four-year, post-secondary institution. Through the data analysis, four essentials features emerged: 1) Program Connections as External Factors, 2) Connections as External Factors in the College Setting, 3) Determination, Self-Advocacy and Willingness to Try New Things as Internal Protective Factors, and 4) Nurturing College Knowledge. Recommendations are shared to further the program in being a degree attainment intervention, in addition to a college access strategy. These include: providing development to educators in behavior management and inclusion, integrating parent involvement throughout the curriculum, providing continual support to alumni and establishing stronger partnerships with surrounding colleges. As a result of this study, leaders in secondary and post-secondary education as well as policymakers are able to gain insight on how Upward Bound services in Louisiana can nurture external and internal protective factors of resiliency that assist participants in embracing constructive responses to stressors in the first year of college
The People\u27s Poets: Literature Born of the Texas Singer-Songwriter Movement of the Last Forty Years
Get PDFThe People’s Poets of Texas: Literature Born Within the Singer/Songwriter Tradition of the Last Forty Years is a creative nonfiction exploration of the poetry found within the songs of multiple generations of modern Texas singer/songwriters and a case for the consideration of their work as a genuine regional literature. Studying the roots of Texas music, the musicality of Texan manners of speech and storytelling, and re-examining the Austin, Texas music scene of the 1970s that brought a national focus to the organic, reciprocal manner in which Texas music is traditionally experienced, radically altered the ways in which the songs were written, recorded, and marketed. An examination of this phenomenon allows us to understand that, first, a proliferation of Texas singer/songwriters of unprecedented quality has emerged in recent decades and that, second, a legitimate people\u27s literature is emerging from their song-craft
Barrier spit evolution and primary consolidation of backbarrier facies: West Belle Pass Barrier, LA
Get PDFWest Belle Pass Barrier is a barrier spit that formed during the last delta lobe progradation associated with the Lafourche delta complex. Located on the western flank of the Caminada-Moreau Headland, West Belle Pass Barrier and Raccoon Pass are located downdrift of the Belle Pass jetties. Morphological changes stemming from storms, jetty infrastructure, and an expanding tidal inlet are evaluated using historical shoreline data and imagery. Littoral transport around the jetties combined with inlet growth created a framework wherein sediment is transported through Raccoon Pass and sequestered as a flood-tidal delta. These events aided in the landward migration of West Belle Pass Barrier, which ultimately loaded and consolidated previously unconsolidated facies. A conceptual model illustrating the primary consolidation of backbarrier facies resulting from washover deposits during one storm is presented. The primary consolidation settlement associated with loading near-surface, water-saturated backbarrier facies is substantially larger than current subsidence rates
Investigation and Implementation of a Lifting Line Theory to Predict Propeller Performance
Get PDFNumerous hydrodynamic theories may be used to predict the performance of marine propellers. The goal of this thesis is to investigate and implement a lifting line theory as a program written in FORTRAN and to test its capabilities on some Wageningen B-Series propellers. Special attention is given to the validation of the routines involved in the implementation of the theory. Difficulties were experienced in obtaining results that accurately reflect the published experimental results, and some discussion is included regarding possibilities for the sources of these errors. Also discussed are the results of other lifting line codes and their respective differences from the current implementation