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Working Papers in the Language Sciences (WPLS), Volume 2, Number 1, Spring 2001
No full textWorking Papers in the Language Sciences at the University of Rochester (WPLS: UR) is an online publication of working papers from the University's interdisciplinary language sciences community.Any student or faculty member from the University of Rochester can submit their working papers for consideration.For more information, please visit the Working Papers in the Language Sciences homepage.Table of ContentsEditors: James S. Magnuson and Katherine CrosswhitePredicting syllabicity and moraicity in Dihovo Macedonianby Katherine Crosswhite, pp. 1-22The double object construction at the interfacesby Jeffrey T. Runner, pp. 23-51The time-course of processing syntactic dependencies: Evidence from eye movements during spoken narrativesby Rachel S. Sussman and Julie C. Sedivy, pp. 52-70On the interpretation of computational models: The case of TRACEby James S. Magnuson, Delphine Dahan, Michael K. Tanenhaus</p
Figure 3 Dataset - Effect of fluid flow on surface and junctional adhesion molecule expression with or without TNF-α stimulation
No full textThe dataset includes raw images of endothelial cells cultured at varying fluidic shear stress levels with or without inflammatory stimulation in a microfluidc tissue chip. The prism file includes the final figure outline as well as the raw ICAM-1 expression values and VE-cadherin junctional gap width values.This dataset supports Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis, published in Scientific Reports, Vol. 15, Iss. 3227, January 2025.</p
Preservica Metadata Application Profile
No full textThis profile was created to help the University of Rochester Libraries maintain consistent metadata standards throughout the digital collections contained within Preservica. Qualified Dublin Core was selected as the metadata schema because of its ease of use, adaptability, and interoperability.This document is meant to be a reference guide for catalogers/metadata specialists and to showcase the available descriptive options for library staff interested in housing a digital collection in Preservica. Maps to other commonly used metadata schemas are provided to help with metadata migrations.</p
Omeka S Digital Projects Service Level Agreement
No full textThis document outlines the roles and responsibilities for all those stakeholders involved with utilizing the Projects instance of Omeka S. Omeka S is a web content management system (CMS) that allows users to create digital exhibits or projects. The Digital Projects instance will be used for already existing research projects that require unique metadata and which use materials that are part of the University of Rochester Libraries’ unique collections. This instance may also be used for future faculty research projects where the metadata or descriptions are an integral part of the research output beyond a typical exhibit/curatorial approach. Within the scope of this instance will also be digital projects that require the development of/augmentation of plug-ins beyond the generally available options in Omeka S. Stakeholders include digital exhibit creators (curators, students, and library staff), Digital Initiatives and Digital Scholarship who maintain the servers hosting Omeka S as well as maintain the application and its modules.</p
Digital Collaborative Governance Team Document Review Calendar
No full textThis document outlines the review calendar for the documents that govern the operations of the Digital Collaborative Governance Team (DCGT). To ensure that all documents are reviewed in a timely fashion, the review cycle occurs on a rolling and ongoing basis. The documents to be reviewed may include any of the following:· Service Level Agreements (SLA)· Service Models· Service Overviews· Policies· Metadata Application Profiles (MAP)· Governance documentation</p
Investigating the Relationship of LINE-1 Expression and SIRT6 Rescue Across Rodent Species
No full textAging-associated inflammation, or ‘inflammaging” is a driver of multiple age-associated diseases. Cyclic GMP-AMP Synthase (cGAS) is a cytosolic DNA sensor that functions to activate interferon response upon detecting viral DNA in the cytoplasm. cGAS contributes to inflammaging by responding to endogenous signals such as damaged DNA or LINE1 (L1) cDNA which forms in aged cells. While cGAS knockout mice are viable their aging has not been examined. Unexpectedly, we found that cGAS knockout mice exhibit accelerated aging phenotype associated with induction of inflammation. Transcription of L1 elements was increased in both cGAS knockout mice and in cGAS siRNA knockdown cells associated with high levels of cytoplasmic L1 DNA and expression of ORF1 protein. Cells from cGAS knockout mice showed increased chromatin accessibility and decreased DNA methylation on L1 transposons. Stimulated emission depletion microscopy (STED) showed that cGAS forms nuclear condensates that co-localize with H3K9me3 heterochromatin marks, and H3K9me3 pattern is disrupted in cGAS knockout cells. Taken together these results suggest a previously undescribed role for cGAS in maintaining heterochromatin on transposable elements. We propose that loss of cGAS leads to loss of chromatin organization, de-repression of transposable elements and induction of inflammation resulting in accelerated aging.</p
Data Bloom 2024: Visualize with Python
No full textData Bloom: Visualize with Python was presented via Zoom on Friday, November 1, 2024 as part of the Fall 2024 Data Bloom workshop series.Want to use Python to visualize your dataset? In this workshop, we will use libraries such as Matplotlib, Seaborn, and more to create meaningful plots. Learn how to tweak various elements to effectively share your story and make your viz interactive. No prior programming experience is required.This record includes the PowerPoint slide deck, Python notebooks, and recorded session with subtitles.</p
Rules to Infinity: The Normative Role of Mathematics in Scientific Explanation
No full textOne of the central aims of science is to provide explanations of natural phenomena. What role does mathematics play in achieving this aim? How does mathematics contribute to the explanatory power of science? Rules to Infinity defends the thesis that mathematics contributes to the explanatory power of science by expressing conceptual rules that allow for the transformation of empirical descriptions. It claims that mathematics should not be thought of as describing, in any substantive sense, an abstract realm of eternal mathematical objects, as traditional Platonists have thought. This view, which Mark Povich calls "mathematical normativism," is updated with contemporary philosophical tools, which are used to form the argument that normativism is compatible with mainstream semantic theory. This allows the normativist to accept that there are mathematical truths, while resisting the Platonistic idea that there exist abstract mathematical objects that explain such truths. There is a distinction between scientific explanations that are in some sense distinctively mathematical--those that explain natural phenomena in some uniquely mathematical way--and those that are only standardly mathematical, and Povich defends a particular account of this distinction. Rules to Infinity compares normativism to other prominent views in the philosophy of mathematics, such as neo-Fregeanism, fictionalism, conventionalism, and structuralism, and offers an entry point into debates at the forefront of philosophy of science and mathematics as it defends its novel positions.Oxford University PressISBN: 9780197679012</p
Turkish Mothers Reasoning and Judgment around Autonomy
No full textWe surveyed 256 mostly well-educated mothers (M = 36.61 years, SD = 4.66) of 4- to 8-year-olds in Turkey about hypothetical and real-life personal, prudential, and conventional issues. In both contexts, Turkish mothers generally reported granting their children autonomy over personal issues while maintaining authority over prudential and conventional matters, based primarily on concerns about potential harm to the child or others. Higher SES mothers reported providing more autonomy, less control, and having less conflict with their child than lower SES mothers. Mothers reported little use of punitive strategies to resolve conflicts, but negotiation and persuasion were used predominantly by higher SES mothers. Boys were granted more decision-making autonomy than girls, and preschool girls were viewed as more attention-seeking than boys, a pattern that reversed at school age. Turkish mothers balanced granting autonomy and maintaining authority, with higher SES mothers more supportive of autonomy and negotiation in conflicts than lower SES mothers.</p
Walt Whitman Onwards and Outwards
No full textStudents in two of Professor Robert Westbrook's courses in American intellectual history, "The American Mind, 1600-1865" (History 267) and "The American Mind, 1865-1990" (History 268), use manuscript materials as part of a research assignment. This assignment, called "Other People's Mail," requires that students transcribe a document and write an introduction to it, placing the document in its context and suggesting the ways in which it bears on significant themes in the course. The student essay along with transcriptions of the documents and images of the originals letters, have been digitized and included. Individual scanned page images are supplied, along with them compiled into a PDF together for convenience.Please Note: All rights regarding the papers rest with the authors. The images of the manuscripts may not be reproduced without obtaining prior written permission from the Department of Rare Books and Special Collections.This document was adapted from a webpage hosted on the Rare Books, Special Collections, and Manuscripts website, before being converted into a static document and uploaded to URRR on 2024-10-03.</p