56593 research outputs found
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Risk Factors for Perceived Increases in Smoking Due to COVID-19
abstract: Due to the COVID-19 pandemic, declared in March of 2020, there have been many lifestyle changes which have likely influenced tobacco smoking behavior. Such lifestyle changes include lockdowns, stay at home orders, reduction in social cues related to smoking, increased stress, and boredom among other things. This study utilized a cross-sectional survey which looked into these behaviors, primarily perceived risk to COVID-19, and determined if there is an association between perceived risk and education level/race. Education level is a proxy for income and material resources, therefore making it more likely that people with lower levels of education have fewer resources and higher perceived risk to negative effects of COVID-19. Additionally, people of color are often marginalized in the medical community along with being the target of heavy advertising by tobacco companies which have likely impacted risk to COVID-19 as well. (abstract
Lean Processes for Small E-Commerce Product-Based Businesses: An Experimental Study
abstract: In this paper, I discuss my findings from The Toyota Way, 2 Second Lean, and Lean Thinking, I present an analysis of my implementation of lean processes for Page Petal, and I recommend a set of lean philosophies that I found to be successful for e-commerce product-based small businesses. I also focus on how the economy plays an important role in the demand for goods, a major factor in which lean processes will ultimately be successful. The goal of this paper is to demonstrate the value of mindful risk-taking in entrepreneurship and to reveal what was effective with Page Petal in hopes of giving other small businesses insight into how to be successful. (abstract
How Title I Schools Encourage Graduation: Graduation Rates in Title I Schools and Programs Offered
abstract: The purpose of this study was to bring new information to the field of education research on graduation rates and school programming. Research on graduation rates and the effects of school programs exist, however there is not an abundance of research aimed specifically at Title I high schools. The goal was to find what school characteristics might impact graduation rates in this population. The thesis focused on Title I high schools in the Phoenix Union District with a graduating 2019 class of at least 250 students. This limited the effect of variability (school size, location, socioeconomic status). To research this topic, school characteristics were selected including course rigor, mentor programs, and college prep programs, as well as specific schools. To obtain the information, multiple sources were used including the Arizona Department of Education website, school websites, and school administrators/staff. The research revealed that the effect of course rigor, college prep programs, and mentorship on graduation rates in Phoenix Union High Schools is not apparent. Further research should be conducted into other possible causes for the gaps in graduation rates between the Title I high schools in this district. Future research on ELL students and programs in the Phoenix Union district and their effectiveness or lack thereof is also recommended. The research shows that this large demographic negatively correlates with the overall graduation rates at the six schools researched. (abstract
The Overlooked Legacy of the Emperor Galerius
abstract: This thesis focuses on the life of the Roman Emperor Galerius, with special attention paid to his military campaigns in the east against the Sassanid Empire. Because of a lack of primary sources, Galerius's potential route into Armenia and his two engagements against the Sassanids have been recreated in this thesis. Potential answers to the lack of information were revealed through the analysis of primary sources from different time periods in which similar scenarios occurred between the Romans and Parthians/Sassanids. In addition to the Eastern Campaign, the Christian primary sources are scrutinized due to their bias in portraying Galerius as a bloodthirsty monster. Overall, this thesis puts forth potential answers to the missing information about Galerius's campaign in the East and recreates his legacy as an important figure in Roman history, not just an individual who persecuted Christians. (abstract
Fetal Androgen & Childhood Adversity: Relations with Self-Compassion, Compassion for Others, Empathy, and Post-Traumatic Stress Disorder Susceptibility
abstract: Fetal androgen exposure and childhood experiences are believed to contribute to the development and organization of the hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes, which are responsible for the regulation and release of stress and sex hormones, respectively. Evidence suggests the HPA and HPG axes can couple in response to childhood adversity, and that hormonal dysregulation contributes to psychopathological disorders such as anxiety and depression. Recent research also suggests self-compassion interventions could reduce PTSD symptoms, and that the experience of childhood trauma is related to increased empathy. Still, little is known regarding the impact of fetal androgen exposure on PTSD susceptibility and the relationships between self-compassion, compassion for others, and empathy. The current study aims to determine whether fetal androgen exposure mitigates PTSD susceptibility, and to clarify the relationships between empathy, compassion for others, self-compassion, and PTSD symptoms. A sample of 208 adults completed an online survey designed to measure fetal androgen exposure, childhood maltreatment, self-compassion, compassion for others, empathy, and PTSD symptoms. Findings show a significant difference in PTSD symptoms between individuals in high and low fetal androgen exposure groups, and significant correlations were discovered between empathy and compassion for others, empathy and self-compassion, but not compassion for others and self-compassion. Future studies could explore the extent to which fetal androgen exposure influences PTSD symptom susceptibility and the clinical implications therein. (abstract
The Sustainability Issue: Fast Fashion & Overconsumption
abstract: This thesis project consists of a digital creative booklet educating consumers on the issue of fast fashion and the overconsumption of clothing. It also consists of easy to follow recommendations for consumers to begin their sustainable journey in fashion as well as resources for them to use to educate themselves further. The goal of the document is to be an introductory educational tool that spreads awareness while also being easy to understand and visually appealing. (abstract
StreetWise: A skill service for students by students
abstract: Stress for college students is nothing new and as more kids go to college the number of cases are on the rise. This issue is apparent at colleges across the nation including Arizona State University. StreetWise aims to help students prevent or appropriately deal with stress through interactive lessons teaching students life skills, social skills, and emotional intelligence.
In order to prove the value of our service, StreetWise conducted a survey that asked students about their habits, thoughts on stress, and their future. Students from Arizona State University were surveyed with questions on respondent background, employment, number one stressor, preferred learning method, and topics that students were interested in learning. We found that students’ number one stressor was school but was interested in learning skills that would prepare them for their future after graduation. We used the results to make final decisions so that StreetWise could offer lessons that students would get the most value out of. This led to us conducting a second survey which included mock ups of the website, examples of interactive lesson plans, and an overview of the app. Students from the first survey were surveyed in addition to new respondents. This survey was intended for us to ensure that our service would maintain its value to students with the aesthetic and interface that we envisioned. (abstract
Predicting the Binding Interactions of TNFR2 and PD-L1 on LT-ɑ, TRAF2, and CD80
abstract: The field of biomedical research relies on the knowledge of binding interactions between various proteins of interest to create novel molecular targets for therapeutic purposes. While many of these interactions remain a mystery, knowledge of these properties and interactions could have significant medical applications in terms of understanding cell signaling and immunological defenses. Furthermore, there is evidence that machine learning and peptide microarrays can be used to make reliable predictions of where proteins could interact with each other without the definitive knowledge of the interactions. In this case, a neural network was used to predict the unknown binding interactions of TNFR2 onto LT-É‘ and TRAF2, and PD-L1 onto CD80, based off of the binding data from a sampling of protein-peptide interactions on a microarray. The accuracy and reliability of these predictions would rely on future research to confirm the interactions of these proteins, but the knowledge from these methods and predictions could have a future impact with regards to rational and structure-based drug design. (abstract
Comparing Profiles of the Urinary Microbiome between Patients with Urinary Disease
abstract: Urologic diseases interstitial cystitis (IC), overactive bladder (OAB), and urinary tract infection (UTI) affect tens of millions of people per year in the US alone. The human microbiome consists of a diverse community of bacteria (bacteriome) and viruses (virome) harbored in each individual that contributes to health and disease. Little is known about how the microbiome impacts urinary disorders. Using next-generation metagenomic sequencing, we characterized the urinary bacteriome and virome of patients with urinary disorders (IC, OAB, and UTI) and healthy controls. We show that the bacteriome was distinctly altered in patients by their respective urinary disorder. IC was characterized by a distinct prevalence of the genus Lactobacillus, while OAB was characterized by the genus Bacteroides, and UTI was characterized by Comamonas. IC, OAB, and UTI all also had significantly differed virome profiles from healthy individuals. In particular, we found that Lactobacillus phages were significantly associated with IC and Corynebacterium virus was associated with UTI samples, meanwhile no particular virus was correlated with OAB samples. Overall, we show that changes in the urinary microbiome are associated with incidence and spectrum of urinary diseases. These findings could lead to new microbiome modalities of treatment. (abstract