13856 research outputs found
Sort by
CpG寡脱氧核苷酸、包含其的免疫组合物及组合物用于制备治疗以刺激免疫反应的药物的应用
No full text[[abstract]]在这里公开一种CpG寡脱氧核苷酸(CpG‑ODN)，其是作为开发用于在不同物种中使用作为佐剂的有效免疫刺激。TLR9为CpG‑ODN的细胞受体，且目前开发的CpG‑ODN对兔子的TLR9具有低活性。本文中，包含约11‑14个脱氧核苷酸的GACGTT或AACGTT基序的CpG‑ODN类型展现出对兔子的TLR9具有有效的免疫刺激活性，且能够在兔子中提升较少毒性且有效的抗体反应
GLK介在疾患の治療薬同定方法
No full text[[abstract]]Methods for identifying a therapeutic agent for treating a Germinal Center Kinase (GCK)-Like Kinase (GLK)-mediated disease are disclosed. Methods for detecting a modulation of GLK signaling by a test compound are disclosed. Also disclosed are methods for detecting the presence and/or severity of an autoimmune disease and/or cancer
Cross-linked oxidated hyaluronic acid for use as a vitreous substitute
No full text[[abstract]]A composition comprising a hydrogel polymer for use as a vitreous substitute for replacing the vitreous humor of an eye is disclosed. The hydrogel polymer comprises oxidated hyaluronic acid and a dihydrazide, in which the dihydrazide cross-links the oxidated hyaluronic acid. The hydrogel polymer exhibits the following properties: a) transparent and colorless; and b) transforming from a liquid state into a gel-matrix at 37° C. These characteristics make it useful as a vitreous humor substitute
組成物
No full text[[abstract]]A composition comprising a polymer that comprises oxidated hyaluronic acid cross-linked by a dihydrazide is disclosed. The polymer is a hydrogel exhibiting the following properties: a) transparent and colorless; and b) transforming from a liquid state into a gel-matrix at 37° C. These characteristics make it useful as a vitreous humor substitute
Cell culture device and electromagnetic stimulation cell culturing system having the same
No full text[[abstract]]A cell culture device comprises a top layer, a diffusion layer, and a suspension layer. The diffusion layer comprises at least one diffusion channel. The suspension layer comprises multiple suspension units. The multiple suspension units are connected to the diffusion channel. A fluid is conducted through the diffusion channel and flow into the suspension units for drop suspended. Cells are cultivated in the fluid suspended in the suspension unit. The cell culture device can be used in an electromagnetic cell culturing system. The electromagnetic cell culturing system is a combination of hanging drop method, microfluidic technology and electromagnetic stimulation. The electromagnetic cell culturing system can improve the growth of cells and also is capable of continuously providing culture medium into the cell culture device. The cell culture device can be used to cultivate large quantity of cells with high productivity and stable quality
[[alternative]]Method for preventing or treating urological chronic pelvic pain syndrome
No full text[[abstract]]本揭露提供一種氧化鈰奈米顆粒(CeNPs)作為製備預防或治療泌尿系統慢性骨盆腔疼痛症候群(UCPPS)的藥物的用途，包括向有其需要的個體施用有效量的氧化鈰奈米顆粒。本揭露復提供一種醫藥組成物作為製備預防或治療泌尿系統慢性骨盆腔疼痛症候群的藥物中的用途，該醫藥組成物包括有效量的氧化鈰奈米顆粒及其藥學上可接受的載體
流体力学シャトリングチップ機器,及び,分離した単一細胞を捕捉する方法
No full text[[abstract]]A hydrodynamic shuttling chip device comprising an array of single-cell trapping units is disclosed. Each unit comprises: (a) an incoming channel with a cell capture site; (b) a cell culture chamber located posterior to the cell capture site, having a receiving site spaced apart from the cell capture site at a distance of g; (c) a trapping channel located between the cell capture site and the receiving site; (d) a chamber channel located posterior to and in fluidic connection with the cell culture chamber; and (e) a by-pass channel, located lateral to the incoming channel, chamber and chamber channel and having a first end and a second end opposite to the first end, the first end branching out from the incoming channel immediately prior to the cell capture site and the second end joining the chamber channel. A method of capturing single cells of more than one type is also disclosed
Mesoporous silica nanoparticles for oil absorption
No full text[[abstract]]A method for prevention and/or treatment of steatorrhea in a subject is disclosed. The method comprises administering to the subject a composition comprising mesoporous silica nanoparticles (MSNs) in an amount effective for prevention and/or treatment of steatorrhea in the subjec
[[alternative]]Use of the composition comprising mesoporous silica nanoparticles
No full text[[abstract]]本發明係揭露一種組成物，包含有效量之中孔洞矽奈米粒子(mesoporous silica nanoparticles，MSNs)以用於需要避免及/或治療脂肪痢(steatorrhea)之主體。本發明也揭露一種組成物用於露出液態油脂至中孔洞矽奈米粒子並造成液態油脂膠化及/或固化，或一種組成物用於露出在主體之腸中之液體食用油脂至中孔洞矽奈米粒子並造成在主體之腸中之液體食用油脂膠化及/或固化，或一種組成物用於降低液體食用油脂之腸吸收
Method and system for destroying adipose tissue non-invasively and accelerating lipid metabolism
No full text[[abstract]]The present disclosure is to destroy adipose tissue non-invasively by using focused ultrasound (FUS) and to increase the treatment efficiency by the synergy of the novel FUS and electrical stimulation. Lipid can be released from the destroyed adipocytes