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    第6章 カンボジアにおける「ビジネスと人権」―政府の取組みと企業からの働きかけの可能性―

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    第5回 フィリピン——「特別な関係」が根底に

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    articl

    The Gulfization of Stock Markets:Evidence on Regional Spillovers from GCC to MENA, Asia, and Africa

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    application/pdfIDP000983_001This study analyzes stock market “Gulfization,” whereby spillovers from the Gulf Cooperation Council affect equity markets in capital-receiving countries. Using weekly data from 2000–2023, we estimate pairwise VAR models and construct a spillover index based on cumulative impulse responses, which is linked to foreign direct investment, remittances, and trade. Spillovers are strongest in MENA—particularly Egypt, Jordan, and Palestine—moderate in parts of Asia, and weak in Africa. Correlation results show that remittances and trade, rather than FDI, explain spillovers. We conclude that Gulfization reflects a structural form of regional financial interdependence.technical repor

    第6回 ラオス——出鼻をくじかれる対米輸出

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    Key messages and Findings

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    application/pdfSNT001900_002technical repor

    資料を守るライブラリアン──省エネしつつ、カビを防ぐ

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    Puzzling Art Market Relationships: Quantifying Provenance to Model Historic Prices of Seventeenth- to Eighteenth-century French Art

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    Previous studies of art price modeling relied on RSR, hedonic, or network modeling techniques to interpret a set of variables’ relationship to perceived art prices. There was an adversity in quantifying provenance record as it proved to be a laborious task riddled with limitations in the dataset. Existing research has not analyzed how aristocratic ownership, art dealers, and auction houses interacted within a given network of the art market. This thesis explores the relationship between provenance and historical seventeenth- and eighteenth-century French art prices in the British and French art market by using a hybrid approach integrating hedonic modeling with network analysis. Using data from the Getty Provenance Index, this study focuses on three provenance indicators: aristocratic ownership, art dealer involvement, and auction house involvement. The key findings supported the importance of auction houses in driving art prices and the heterogenous relationship present within the art market. This work contributes to the growing field of quantitative art market analysis to better understand how art is valued over time.Applied Mathematic

    Simultaneous tracking of many neuromodulatory signals in the awake mouse brain

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    Most neurons express receptors for dozens of neuromodulatory molecules. Concentrations of these molecules vary widely in the brain interstitial space across time and space, and their influences overlap and combine to modulate neural activity. While current tools allow for small numbers of such signals (usually one or two) to be tracked at the same time, no real-time methods exist to scale up this molecular dimensionality and reach a complete accounting of dynamic changes in local neuromodulator concentrations in the awake brain. To begin to address this gap, we have developed a probe to track a dozen or more neuropeptide and neuromodulator concentrations in various brain regions in mice. Our probe consists of an emerging family of genetically encoded fluorescent sensors, the G protein-coupled receptor activation-based (GRAB) sensors, expressed in cultured cells and immobilized at the front of a gradient refractive index (GRIN) lens for 3D two-photon imaging. We validate this probe both in vitro, by sequentially placing it cells-first into small volumes (≤20 μL) of fluids with known concentrations of each sensor ligand while imaging the cells through the lens, as well as ex vivo by pressing it against a live brain slice and evoking neuromodulator release, detecting parallel molecular concentrations down to nanomolar levels. We have also validated the probe in vivo by acutely implanting it in the lateral ventricles of awake, behaving mice. We observed rapid shifts in cerebrospinal fluid signal concentrations across seconds to minutes, both spontaneously and in response to peripheral drug administration. Our novel, scalable approach enables rapid in situ profiling of a panel of molecules of interest in very small fluid samples and tissue regions in vivo and ex vivo. In future, this method can be used to study how the rich ensemble of time-varying concentrations of chemical signals correlates with and controls the activity of various cell types throughout the brain.Medical Science

    Tolerating the Intolerable

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