MRC Lifecourse Epidemiology Unit

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    Atypical presentation of visceral leishmaniasis from non-endemic region

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    A case of atypical and acute presentation of visceral leishmaniasis from non-endemic region, characterised by exudative pleural effusion and hepatitis is reporte

    Ovarian Fibroma with Meigs Syndrome associated with Elevated CA125 - A Rare Case

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    Postmenopausal women with solid adnexal masses, ascites and pleural effusion with elevated CA 125 are highly suggestive for malignant ovarian tumor. However in literature 28 cases Meigs syndrome (Benign ovarian tumor, ascites and right pleural effusion) with raised CA 125 have been reported. We report a case of Meigs syndrome caused by right ovarian fibroma with elevated serum CA125 level in a postmenopausal woma

    Reasoning about Social Semantic Web Applications using String Similarity and Frame Logic

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    Social semantic Web or Web 3.0 application gained major attention from academia and industry in recent times. Such applications try to take advantage of user supplied meta data, using ideas from the semantic Web initiative, in order to provide better services. An open problem is the formalization of such meta data, due to its complex and often inconsistent nature. A possible solution to inconsistencies are string similarity metrics which are explained and analyzed. A study of performance and applicability in a frame logic environment is conducted on the case of agent reasoning about multiple domains in TaOPis - a social semantic Web application for self-organizing communities. Results show that the NYSIIS metric yields surprisingly good results on Croatian words and phrases

    Une Classe de Concepts

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    Cet article décrit la construction, d'essence philosophique d'une classe de concepts, dont la structure et les propriétés présentent un intérêt dans plusieurs domaines. L'accent est mis ici sur les applications dans le domaine de l'analyse paradigmatique de la présente taxinomie et la propose en tant qu'alternative à la classification proposée par Greimas

    Analyzing the Facebook Friendship Graph

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    Online Social Networks (OSN) during last years acquired a\ud huge and increasing popularity as one of the most important emerging Web phenomena, deeply modifying the behavior of users and contributing to build a solid substrate of connections and relationships among people using the Web. In this preliminary work paper, our purpose is to analyze Facebook, considering a signi�cant sample of data re\ud ecting relationships among subscribed users. Our goal is to extract, from this platform, relevant information about the distribution of these relations and exploit tools and algorithms provided by the Social Network Analysis (SNA) to discover and, possibly, understand underlying similarities\ud between the developing of OSN and real-life social networks

    Virtual R&D teams and SMEs growth: A comparative study between Iranian and Malaysian SMEs

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    This paper explores potential advantages of using virtual teams for small and medium-sized enterprises (SMEs) with a comprehensive review on various aspects of virtual teams. Based on the standing of the pertinent literature's, attempt has been made to study the aspects by online survey method in Iran and Malaysia. In both countries, SMEs play an important role in their economies, employments, and capacity building. Virtual R&D team can be one of the means to increase SMEs efficiency and competitiveness in their local as well as global markets. In this context, surveys have been conducted to evaluate the effects of virtuality to the growth of SMEs. The study addresses some differences between two countries in engaging virtual research and development (R&D) teams in their SMEs. It is observed that there is a significant difference between the SMEs turnover that employed virtual team and that did not employ the virtual team. The way for further studies and recommend improvements are proposed

    Erythromycin induced Torsade de Pointes in a Methadone maintenance patient:Case Report

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    Objective: This case report highlights the risk of Torsade de Pointes (TdP), a life threatening cardiac arrhythmia in a heroin dependent patient receiving methadone substitution therapy who was prescribed erythromycin for upper respiratory tract infection. Method: We report a case of a 35-year-old Malay man on methadone maintenance treatment who developed TdP possibly due to drug interaction between methadone and erythromycin. Results: The patient reported feeling unwell, chest pain and feeling dizzy after consuming 2 doses of erythromycin. ECG monitoring showed prolonged rate-corrected QT interval leading to TdP. The patient was admitted to the ward where the cardiac arrhythmia ceased following methadone discontinuation. This cardiac arrhythmia was most likely due to drug interaction between methadone and erythromycin (an enzyme inhibitor) which led to an increase in methadone concentration and potentiated the adverse effects. Conclusion: As methadone is a beneficial treatment for heroin dependent patients, the risk of cardiac arrhythmia is of great concern. To avoid complications of drug interaction, patients on methadone therapy should be advised to seek medical assessment before taking other drugs. As TdP is life threatening, it is thus important that physicians and psychiatrists involved in the treatment of heroin dependent patients on methadone substitution therapy be made aware of this risk

    Substance Abuse And Violence Behavior

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    Objectives: This paper examines the relationship of various licit/illicit substances and their association with violent behaviors. Methodology: The selection of related articles was searched via various database including google scholar, ovid and sciencedirect search engines. Results: Most of the literatures suggest presence of association of various substance use with violent behavior but no definite causal relationship between them. Conclusion: Further study is needed to determine the extended relationship in between substance use and violence

    Evaluation of Computational Grammar Formalisms for Indian Languages

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    Natural Language Parsing has been the most prominent research area since the genesis of Natural Language Processing. Probabilistic Parsers are being developed to make the process of parser development much easier, accurate and fast. In Indian context, identification of which Computational Grammar Formalism is to be used is still a question which needs to be answered. In this paper we focus on this problem and try to analyze different formalisms for Indian languages

    Singer Revisited: Cosmopolitanism, Global Poverty and Our Ethical Requirements

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    A commonly held view is that giving to the poor is superogatory i.e. that while it is a good thing to do, it is not morally wrong for us not to do so. This essay sets out to show that for the affluent in the world giving to the poor is not superogatory but is rather a moral obligation. The paper critiques Singer’s famous argument in ‘Famine, Affluence and Morality’ and finds that although the argument is a cogent and powerful one, Singer, when trying to apply the argument to how we should act, somewhat skews the argument’s real implications. Furthermore it is argued that a cosmopolitan concern for the global poor is the morally correct response to have, and defends this view by examining the proper effect that that aspects like geographical distance, nationality, reciprocity, and the nature of the global economic system should have on our moral considerations. In conclusion it is argued that as the way that each person spends his/her money is a reflection of what he/she values, then for many of us in positions of affluence, in order to be moral, much more should be done in order to help those experiencing dire, life-threatening poverty across the globe

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