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    4276 research outputs found

    Diagnosis of Rosai-Dorfman Disease by Fine Needle Aspiration Cytology in a Case with Cervical Lymphadenopathy and Nasal Mass

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    We report a case of Rosai-Dorfman Disease, a rare non neoplastic proliferative disorder of the cells of macrophage-histiocyte family, in a case with cervical lymphadenopathy and nasal mass diagnosed by fine needle aspiration cytology

    Motion as manipulation: Implementation of motion and force analogies by event-file binding and action planning\ud

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    Tool improvisation analogies are a special case of motion and force analogies that appear to be implemented pre-conceptually, in many species, by event-file binding and action planning. A detailed reconstruction of the analogical reasoning steps involved in Rutherford's and Bohr's development of the first quantized-orbit model of atomic structure is used to show that human motion and force analogies generally can be implemented by the event-file binding and action planning mechanism. Predictions that distinguish this model from competing concept-level models of analogy are discussed, available data pertaining to them are reviewed, and further experimental tests are proposed

    Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation

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    Metaplastic breast carcinoma is very rare neoplasm which contains mixture of carcinomatous (epithelial) and sarcomatous (mesenchymal) elements in variable proportion. Metaplastic carcinoma with chondroid differentiation is even rarer. We report a case of metaplastic carcinoma with extensive chondroid differentiation as there is paucity of information regarding pathological features and clinical outcomes for these rare tumors. Tumor had characteristic definite areas of classic infiltrating duct carcinoma with abundant chondromyxoid matrix, focal areas of chondrosarcoma and cartilagenous metaplasia. Tumour cells were immunoreactive for S-100, ER, and PR. When pathologist encounter breast tumor with chondroid differentiation, careful gross sampling, histopathology and immunoreactivity for mesenchymal and epithelial component are most useful to differentiate metaplastic carcinoma from malignant phylloides tumors and malignant adenomyoepithelioma

    A complete evaluation of the antioxidant and antimicrobial potential of Glycine max

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    Vegetable soybean is rich in phytochemicals beneficial to the human being and is therefore considered a neutraceutical or a functional food crop. Soybean has antioxidative activity and protects tissues from oxidative stress-induced injury. Although isoflavones present in soy are believed to be major components responsible for the antioxidative activity, a recent study showed that anthocyanins present in black soybean had strong antioxidative potential.The present study focuses on both the antioxidant and antimicrobial potential of Glycine max

    RNA Synthesis in the Tracheal Epithelial Cells of Aging Mice as Revealed by Electron Microscopic Radioautography

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    For the purpose of studying the aging changes of macromolecular synthesis in the tracheal epithelial cells of experimental animals, we studied 10 groups of aging mice during development and aging from fetal day 19 to postnatal month 24. They were injected with 3H-uridine, a precursor for RNA synthesis, sacrificed and the tracheal tissues were taken out, fixed and processed for light and electron microscopic radioautography. On many radioautograms the localization of silver grains demonstrating RNA synthesis in tracheal epithelial cells in respective aging groups were analyzed qualitatively and quantitatively. The number of mitochondria per cell, the number of labeled mitochondria with silver grains and the number of silver grains in each cell in respective aging groups were analyzed quantitatively in relation to the aging of animals. The results revealed that the RNA synthetic activity as expressed by the incorporations of RNA precursor, i.e., the number of silver grains in cell nuclei, cell organelles, changed due to the aging of animals. The number of mitochondria, the number of labeled mitochondria and the mitochondrial labeling index labeled with silver grains were counted in each tracheal epithelial cell. It was demonstrated that the number of mitochondria increased from embryonic day 19 to postnatal newborn day 1, 3, 9, 14, adult month 1, 2, reaching the maximum and kept plateau, while the number of labeled mitochondria increased from embryonic day 19 to postnatal adult month 2, reaching the maximum but the labeling indices showing RNA synthesis increased from embryonic day 19 to postnatal newborn day 14 and adult month 1 and decreased to year 2, indicating the aging changes. Based upon our findings, available literature on macromolecular synthesis in mitochondria of various cells are reviewed

    Spread of hoax in Social Media

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    We discuss the way of hoax spreading as gossip and rumor throughout the social media, i.e.: Twitter, by observing an empirical case in Indonesia. We discuss the spreading factor of the gossip in the social media and see the epidemiology of the propagation hoax before and after the hoax being clarified in the conventional mass media. The discussions brought us to the open enrchiment analysis of the sociology of gossip and rumors within the online services like Twitter for future observation of human behavior

    A Speech Act Calculus. A Pragmatised Natural Deduction Calculus and its Meta-theory

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    Building on the work of Peter Hinst and Geo Siegwart, we develop a pragmatised natural deduction calculus, i.e. a natural deduction calculus that incorporates illocutionary operators at the formal level, and prove its adequacy

    Reenactment: An embodied cognition approach to meaning and linguistic content

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    A central finding in experimental research identified with Embodied Cognition (EC) is that understanding actions involves their embodied simulation, i.e. executing some processes involved in performing these actions. Extending these findings, I argue that reenactment – the overt embodied simulation of actions and practices, including especially communicative actions and practices, within utterances – makes it possible to forge an integrated EC-based account of linguistic meaning. In particular, I argue: (a) that remote entities can be referred to by reenacting actions performed with them; (b) that the use of grammatical constructions can be conceived of as the reenactment of linguistic action routines; (c) that complex enunciational structures (reported speech, irony, etc.) involve a separate level of reenactment, on which characters are presented as interacting with one another within the utterance; (d) that the segmentation of long utterances into shorter units involves the reenactment of brief audience interventions between units; and (e) that the overall meaning of an utterance can be stated in reenactment terms. The notion of reenactment provides a conceptual framework for accounting for aspects of language that are usually thought to be outside the reach of EC in an EC framework, thus supporting a view of meaning and linguistic content as thoroughly grounded in action and interaction

    Generalized Louvain Method for Community Detection in Large Networks

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    In this paper we present a novel strategy to discover the community structure of (possibly, large) networks. This approach is based on the well-know concept of network modularity optimization. To do so, our algorithm exploits a novel measure of edge centrality, based on the k-paths. This technique allows to efficiently compute a edge ranking in large networks in near linear time. Once the centrality ranking is calculated, the algorithm computes the pairwise proximity between nodes of the network. Finally, it discovers the community structure adopting a strategy inspired by the well-known state-of-the-art Louvain method (henceforth, LM), efficiently maximizing the network modularity. The experiments we carried out show that our algorithm outperforms other techniques and slightly improves results of the original LM, providing reliable results. Another advantage is that its adoption is naturally extended even to unweighted networks, differently with respect to the LM.\u

    Extraction and Analysis of Facebook Friendship Relations

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    Online Social Networks (OSNs) are a unique Web and social phenomenon, affecting tastes and behaviors of their users and helping them to maintain/create friendships. It is interesting to analyze the growth and evolution of Online Social Networks both from the point of view of marketing and other of new services and from a scientific viewpoint, since their structure and evolution may share similarities with real-life social networks. In social sciences, several techniques for analyzing (online) social networks have been developed, to evaluate quantitative properties (e.g., defining metrics and measures of structural characteristics of the networks) or qualitative aspects (e.g., studying the attachment model for the network evolution, the binary trust relationships, and the link prediction problem).\ud However, OSN analysis poses novel challenges both to Computer and Social scientists. We present our long-term research effort in analyzing Facebook, the largest and arguably most successful OSN today: it gathers more than 500 million users. Access to data about Facebook users and their friendship relations, is restricted; thus, we acquired the necessary information directly from the front-end of the Web site, in order to reconstruct a sub-graph representing anonymous interconnections among a significant subset of users. We describe our ad-hoc, privacy-compliant crawler for Facebook data extraction. To minimize bias, we adopt two different graph mining techniques: breadth-first search (BFS) and rejection sampling. To analyze the structural properties of samples consisting of millions of nodes, we developed a specific tool for analyzing quantitative and qualitative properties of social networks, adopting and improving existing Social Network Analysis (SNA) techniques and algorithms

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