4276 research outputs found
Sort by
A Study on Proteolytic Enzyme Activity in the Erythrocytes of Diabetic Patients
No full textThe present study demonstrates the possibility of increased proteolytic activities in diabetic individuals. Proteolytic activity was measured by the amount of amino group released by the erythrocyte lysate of the diabetic individual using phenylhydrazine treated hemoglobin as substrate. The proteolytic activity in erythrocyte lysates against oxidatively damaged hemoglobin was significantly increased in diabetic individuals compared to controls (p<0.001).The result of this study indicates that in diabetic individuals, proteolytic enzymes degrade many oxidatively altered proteins preventing the accumulation of altered and damaged proteins in the cell
Contamination of Sachet Water in Nigeria: Assessment and Health Impact
No full textAdequate supply of fresh and clean drinking water is a basic need for all human beings. Water consumers are frequently unaware of the potential health risks associated with exposure to water borne contaminants which have often led to diseases like diarrhoea, cholera, dysentery, typhoid fever, legionnaire’s disease and parasitic diseases. The inadequacy of pipe borne water-supply in Nigeria is a growing problem; as a result people resort to buying water from vendors, and sachet or bottled water became a major source of drinking water. Although, portable and affordable, the problems of its purity and other health concerns have begun to manifest. Sachet water have been reported to contain bacteria such as Bacillus sp., Pseudomonas sp., Klebsiella sp., Streptococcus sp., and oocysts of Cryptosporidia sp. Apart from environmental contaminants, improper storage and handling by vendors also poses a serious threat to the health of the ignorant consumers. This paper tends to review the quality of these ‘pure water’; its physical examination, microbial assessments, its impacts on health, and the various strategies adopted by the concerned authorities to regulate this thriving industry
Olfactory Neuroblastoma: Diagnostic Difficulty
No full textOlfactory neuroblastoma is an uncommon malignant tumor of sinonasal tract arising from the olfactory neuro epithelium. The olfactory neuroblastomas presenting with divergent histomorphologies like, epithelial appearance of cells, lacking a neuro fibrillary background and absence of rosettes are difficult to diagnose. Such cases require immunohistochemistry to establish the diagnosis. We describe the clinical features, pathological and immunohistochemical findings of grade IV Olfactory neuroblastoma in a 57 year old ma
Inflammatory Pseudo Tumour of Prostate
No full textA 60 year old man presented with history of overflow incontinence, requiring catherization. Digital rectal examination revealed non tender grade II prostatomegaly. Patient underwent transurethral resection of prostate and specimen was sent for histopathological examination. The specimen revealed spindle cell proliferation interspersed with chronic inflammation. Immunohistochemical staining was positive for smooth muscle actin and desmin. A final diagnosis of inflammatory pseudotumour of prostate was made. The patient was later discharged and advised for regular follow up. Inflammatory pseudotumour is very rare condition of prostate. They usually follow benign course and does not require radical surgical treatment. So a definitive diagnosis is essential to prevent unnecessary radical procedure
Twin Pregnancy in a Woman with Uterus Didelphys
No full textUterus didelphys is one of the congenital uterine anomalies due to defective medial fusion of mullerian ducts. This anomaly is known to have poor reproductive outcome and women with this condition often have to be treated for infertility. Multiple gestation is rare with this condition. An 18 years old primigravida presenting with threatened abortion at eight weeks, was found to have uterus didelphys. She was managed conservatively, aborted one of the fetuses at 16weeks of gestation, and went till term to deliver a healthy baby by cesarean section
Berardinelli-Seip Syndrome
No full textWe have reported two cases of Berardinelli-syndrome in a family which is a rare autosomal recessive disorder of the adipose tissue, originally described by Berardinelli and Seip, has been reported in approximately 120 patients of various ethnic origins. Assuming that only 1 in 4 patients is reported.Patients present with acanthosis nigricans (dark velvety pigmentation of the skin) in the axilla, neck or groin, severe insulin resistance, high levels of serum insulin and serum triglycerides.The other clinical features consist of enlarged hands, feet and prominent mandible (acromegaloid features), increased sweating, umbilical hernia and lytic lesions (bone appear to be eaten-up on X-rays) in long bones of the upper and lower extremities (arms, forearm, hands, thigh, calf, legs and feet) such as humerus, femur, etc. Hepatomegaly from fatty liver is almost universal and may ultimately lead to cirrhosis. Splenomegaly is common. Nearly all patients have a prominent umbilicus or frank umbilical hernia. Females present with enlarged clitoris, increased body hair, absence of or irregular menstrual cycles, and polycystic ovaries (enlarged ovaries). Only a few affected women have had successful pregnancies, whereas affected men have normal fertilit
Internal and External Influences on the University Teachers in Semester System
No full textThere are so many influences a faculty member has to undergo at the higher education level in universities in semester system. We wanted to comb the universities for the internal and external influences on the university teachers and their consequences in Balochistan. It was done to determine the loss we bear due to the influences on the university teachers in Balochistan, and to generate such influence-free-mechanism in the universities of Balochistan to strengthen the educational milieu in the province. Faculty members play pivotal role in imparting the education at the higher education level in any country. They happen to be the nucleus of the education system. Disturbing and disrupting them in any was is, in effect, disturbing and disrupting the education process. Influencing them, directly or indirectly, halts the true teaching process. It creates many obstacles ranging from class boycotts, hunger strikes to processions and demonstrations either inside the institute or outside the institute. To forge such a composite mechanism not only to control these both internal and external factors in order to streamline the learning and imparting education process but also to afford a healthy and sound teaching environment
Effect of Organic Contaminations on Seed Germination Studies in Tritium Aestivum (L.)
No full textAn attempt has been made for germination studies in Triticum Aestivum (L.) with1,2,4,5-trtrazin. It has a wide range of biological activity covering anticoagulant, bactericidal, fungicidal, neurotropopic. Such a vast uses of 1,2,4,5-Tetrazines, necessitate to concentrate on 1,2,4,5-Tetrazines for studying the germination pattern. The experimental data was used to calculate plant growth which in turn is decided on the basis of parameters such as percentage of germination survival, seedling height, chlorophyll content, SGI, shoot length, root length and vigour index
Antioxidant and Antimicrobial properties of Glycine Max-A review
No full textVegetable soybean is rich in phytochemicals beneficial to the human being and is therefore considered a neutraceutical or a functional food crop. Soybean as a “functional food” that reduces the risk of range of hazardous diseases like atherosclerosis, osteoporosis, various types of cancer (breast, uterus cancer, and prostrate) has attracted people’s attention across the globe. People in India are becoming increasingly aware about the health benefits of consuming soy food. Although isoflavones present in soy are believed to be major components responsible for the antioxidative activity, a recent study showed that anthocyanins present in black soybean had strong antioxidative potential. This review article focuses on both the antioxidant and antimicrobial activity of Glycine max
Minds, Brains and Turing
No full textTuring set the agenda for (what would eventually be called) the cognitive sciences. He said, essentially, that cognition is as cognition does (or, more accurately, as cognition is capable of doing): Explain the causal basis of cognitive capacity and you’ve explained cognition. Test your explanation by designing a machine that can do everything a normal human cognizer can do – and do it so veridically that human cognizers cannot tell its performance apart from a real human cognizer’s – and you really cannot ask for anything more. Or can you? Neither Turing modelling nor any other kind of computational r dynamical modelling will explain how or why cognizers feel