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Reply to comment on accuracy of toric intraocular lens formulas with measured posterior corneal astigmatism of different orientations
The bacterial glycosyltransferase ArnT as a target for development of antimicrobial resistance breakers
The decline of Duverger?: The impact of devolution on party systems in the United Kingdom
Children's participation in early childhood settings: listening to and hearing the voices of children and educators
Dataset for "New parts to play old instruments: A Case Study of Border Bagpipes"
This dataset contains detailed measurements, 3D modellings and technique drawings of a set of Border pipes housed in the University of Edinburgh. The study was conducted in the University of Edinburgh in 2019, focusing on the physical and tonal characteristics of these historical instruments. Researchers, including music historians organologists and instrument makers, will find this dataset valuable for studying the evolution of Border pipes, their craftsmanship, and their sound production. The data provides insights into materials, dimensions, and performance qualities, supporting both academic research and practical instrument reconstruction. Abstract for the article: This article explores the conservation, documentation, and replication of a historically significant set of bagpipes housed in the University of Edinburgh’s collection. Dating from the late 18th century, these bagpipes pose unique challenges due to incomplete historical records, material degradation, and earlier documentation gaps. By employing traditional measuring techniques and modern 3D modelling, this project overcame these challenges to create accurate technical drawings and functional replicas of the instrument. A hybrid model was developed, combining original components with 3D-printed parts, preserving the artifact’s integrity while enabling functionality. This interdisciplinary approach not only provided a deeper understanding of the craftsmanship and cultural context of the bagpipes but also broadened global access through digital resources and educational content. The study highlights the potential of integrating traditional methods with advanced technology in the conservation and study of historical musical instruments. Northern Bridge Consortium and Thomas Dunlop Endorsement funded. Embargoed until 31 December 2025
Phase evolution of strong-field ionization
We investigate the time-dependent evolution of the dipole phase shift induced by strong-field ionization (SFI) using attosecond transient absorption spectroscopy (ATAS) for time delays where the pump-probe pulses overlap. We study measured and calculated time-dependent attosecond transient absorption spectra of the ionic 4→5 in xenon, and present the time-dependent line shape parameters in the complex plane. We attribute the complex dynamics to the contribution of three distinct processes: accumulation of ionization, transient population, and retrapping of excited states arising from polarization of the ground state.<br/
Challenges created by the Austro-Hungarian Empire: Heat reduction through nature-based solutions in Vienna and Budapest
Dense and urbanized European capitals under the Austro-Hungarian empire were developed at the end of the 19th century. In both Vienna (Austria) and Budapest (Hungary), the historic city defense structures were developed into dense, prestigious housing areas with at least four stories. While important cultural heritage, many historically built-up areas are now a challenge for heat reduction and urban planning. In Central Europe, nature-based solutions are being eyed as measures to tackle urban heat islands and the unequal distribution of green areas across cities. In Vienna and Budapest, the local populations are facing growing climate change impacts in the form of heatwaves and tropical nights, which are expected to negatively affect health and wellbeing.Combining the results of urban heat modelling with the results of a survey with an integrated discrete choice experiment conducted in Budapest and Vienna, this study investigated which geographical parts of the cities are more affected than others, which citizens are the most vulnerable and how they perceive their own affectedness. By combining data on actual and perceived impacts of the temperature, urban areas are identified which are in greater need of nature-based solutions. By identifying the residents of these areas, vulnerable social groups requiring city administration’s attention and support are identified and policy recommendations are given. In both Budapest and Vienna heat is felt more intensely and impacts health to a greater extent in neighborhoods with limited access to and poor-quality green areas, while neighborhoods with ample access to public and private green areas are not as strongly impacted by high temperatures. However, residents of Budapest stated to have more experience with heat waves and respondents indicated much higher rates of heat negatively effecting both their wellbeing and their health. This feeling was not confirmed by the heat models – meaning that the difference between perceived heat and actual temperatures is higher in Budapest. For urban planners the results of this study translate into setting clear planning priorities and goals specific to their residents’ needs: To gain the greatest possible benefits for residents and reduce urban heat island effects, nature-based solutions targeting heat reduction should be placed in neighborhoods which demonstrate high heat perception based on social analysis and heat modeling. By using this approach, planners will address both climate change and its impacts on the population in urban environments
The psychosocial impact of pancreatic cancer on caregivers: a scoping review
Background: Family caregivers are essential members of the care team of someone with pancreatic cancer (PC), supporting their physical and psychological needs. Caregivers are often unprepared for this which may cause substantial psychosocial impact. The majority of people with PC are diagnosed at an advanced stage and are not eligible for potentially curative treatment. Therefore, PC caregivers may experience increased psychosocial impact due to the short life expectancy and rapid deterioration associated with PC.Aim/Research question or hypothesis: This scoping review (ScR) aimed to explore the psychosocial challenges faced by caregivers of individuals with PC.Methods: A Joanna Briggs Institute (JBI) mixed methods ScR was conducted across four databases in March 2024 and reported in line with the PRISMA-ScR checklist. Included studies reported on the psychosocial impact of PC on caregivers. A deductive approach, guided by ‘The Cancer Family Caregiving Experience’ model (Fletcher et al., 2012), was taken to extract and synthesise the data.Results: 39 studies were included: 21 qualitative, 13 quantitative, 5 mixed methods. The literature highlighted PC caregivers experienced stress related to caregiving activities, disruptions in their daily life and family relationships, high levels of unmet need, and poorer quality of life compared to other cancer caregivers. They were also at increased risk for various psychiatric disorders. Included studies highlighted the accelerated disease trajectory of PC with studies focusing on diagnosis at an advanced stage and end-of-life care. A persistent lack of support was reported which exacerbated the psychosocial impact.Discussion: PC caregivers experience negative psychosocial impacts, exacerbated by the disease’s trajectory emphasising the importance of early integration of palliative care to mitigate these issues. Feelings of a lack of support were evident, stressing the need for future research on optimal palliative care strategies to minimise this substantial impact. Enhanced supportive measures are crucial for PC caregiver wellbeing
Strong base anion exchange resins for use in a water treatment plant designed to remove brominated trihalomethane (THM) precursors
From 1999 to 2019, a water treatment plant (WTP) on Rathlin Island, Northern Ireland produced potable water with total trihalomethane (TTHM) concentrations consistently above 50 μg/l, sometimes exceeding 100 μg/l, due to the formation of brominated THMs. Therefore, a customised magnetic ion exchange (MIEX®) Mini MICo® WTP was installed at the site. To select the best resins for the system, batch tests on a variety of strong base anion (SBA) exchange resins [Purolite™A520E, Lewatit® S 5128, Jacobi Resinex™ NR-1, 50:50 blend of MIEX® DOC + Purolite™ A520E and 50:50 blend of MIEX® DOC + Purolite™ A300E] showed that all resins in the study effectively reduced brominated THMs and their precursors, bromide (Br−) and dissolved organic carbon (DOC). The 50:50 mix of MIEX® DOC + A520E resins, followed by A520E and S 5128 resins, showed greatest reduction of brominated THMs and their precursors. The 50:50 blend of MIEX® DOC + A520E was selected for the MIEX® Mini MICo® system, which is a first of its kind in the UK and Europe because it uses a blend of resins, while other MIEX® systems use only one type of resin bead. From 2019 to 2024, this WTP dramatically reduced brominated THM concentrations well below statutory drinking water limits. In July 2020 the 50:50 blend of MIEX® DOC + A520E was changed to a more sustainable 40:60 blend ratio, respectively, which resulted in little to no brine waste emission without increases in THMs.<br/