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    The Intention in Invention: A Philosophy of Technical Imagination

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    To reflect on imagination today is not to revisit an exhausted theme, but to re-engage a philosophical question that continues to unsettle inherited epistemologies and ontologies. Our article focuses on one specific regime of imagination: the relation between imagination and technology, approached through the lens of invention. As we explore the particular regime of technical imagination, we aim to overcome the idea that invention should be treated as a purely productive process, a functional response to needs, materials or economic constraints. Because this renders technical imagination only legible within the parameters of technological solutionism or innovation-as-commodity, we rather argue that invention, as a technical activity, mobilizes a specific form of imagination; one that requires a rethinking of technicity itself. We therefore examine how technical imagination engages with the virtuality and potentiality of matter, as it schematizes possibilities and projects relations before they are actualized. In doing so, our main hypothesis is the need to explore the temporal structure of imagination through the concept of technical intention. We argue that in the process of invention, the very operativity of technical imagination rests on intention. Our hypothesis is that technical intention is the active operativity of imagination within the process of invention, and from what emerges the actualization of a concrete technical individual. Within this gesture, the investigation of imagination plays a central role as a vector of ontogenetic individuation, that calls for a form of responsibility adequate to the transformations it sets into motion, grounded in an awareness that invention is never neutral, but always intervenes in the becoming of reality and consequently in the shaping of our societies. It is in this sense that invention must be understood as inherently grounded in technical imagination, and that both of them reclaims their aesthetic, ethical and political stakes

    Remarques sur l’imagination

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    THE NEW AMERICAN WAR FILM. By Robert Burgoyne. Minneapolis: University of Minnesota Press, 2023.

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    Motives and Points of Attachment Influencing Adult Spectator Attendance at High School Football Games

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    In the United States, high school sports is a growing industry segment. Given the rise in media coverage, including digital streaming and television rights, and increased revenue opportunities through ticketing and sponsorship deals, high school athletic staff and other marketing professionals working in this sector can benefit from understanding spectator motives to inform decision-making. Past literature points to distinct differences in spectator motives by level of play, yet high school spectators remain relatively unexplored. This study leveraged a survey (57 items) of attendees’ (N = 564; representative of 217 cities across 22 states) motives (i.e., excitement, family, nostalgia, role model, skill, social, and vicarious achievement) and attachment points (i.e., identification with the community, players, and the team) influencing their attendance behavior while accounting for differences by event type and gender. Multiple regressions tested the proposed research questions, and MANOVA isolated differences based on event type (i.e., special event versus regular season) and gender. Results pinpoint differences in factors affecting attendance among the groups considered. Findings add to the limited literature exploring interscholastic sports and will prove valuable to industry professionals (e.g., athletic directors, coaches, marketing professionals, and sponsors). Keywords: interscholastic sports, attendance, spectator motivation, attachment point

    Risk, Reality, Regulations? Finding what’s reasonable in copyright guidance

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    Copyright guidance at an academic library is often provided at the nexus of the law, University policy, and the personal and professional values of the librarians and users involved in the decision making. An institution’s tolerance for risk (or lack-thereof) can create tension with librarians’ value systems. The law is often vague, leaving lots of room for differences of interpretation between University administrators, librarians, and users. Professional values, like the ones articulated by the ACRL Framework generally align with enhancing/supporting user’s rights and tend towards a copyleft point of view. Institutional risk tolerance complicates decision making further.  Higher levels of risk are generally accepted with research and teaching endeavours, directly in contrast with a lower level of risk acceptable when it comes to compliance with the law (like the Copyright Act). Lack of clarity in the law and institutional risk tolerance can be at odds with professional values, which can confuse users and undermine librarians providing guidance. This article provides a beginning framework for understanding reasonableness in copyright decisions while taking into account the variety of pressures on copyright librarians. A set of cases are used to test the framework and a reasonableness chart is provided to allow for comparison of the cases

    Evaluating the Evidence for Genetics/Genomics in Chronic Pain: An Integrative Literature Review

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    FCs and CAR Ts teamwork makes the dreamwork

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    Chimeric antigen receptor (CAR) T-cell therapy has recently been a huge topic in cancer immunotherapy, however the effect on solid state tumors remains limited due to poor tumor infiltration and persistence. This review is of a study by sun. et al "Dendritic cell/tumor fusion cell vaccine combined with EGFRvIII-specific nanobody CAR T cells enhances antitumor efficacy against glioblastoma."; this study uses nanobody-based CAR T cells (Nb-CAR Ts), that camelid-derived single-domain antibodies to reduce steric hindrance, which has been shown to improve tumor penetration when compared to traditional CAR receptors. They used EGFRvIII-specific Nb-CAR Ts along with a dendritic cell/tumor fusion cell (FC) to target glioblastoma. EGFRvIII Nb-CAR Ts demonstrated enhanced proliferation, activation, cytokine production, and antigen-specific cytotoxicity in vitro. Key tests showed the effectiveness of the NB CarT cell alone when compared to control groups-- both in vivo and in vitro. NB CarT cell + FC had improved outcomes, both in vivo and in vitro when compared to NB CarT cell alone, FC alone, or NB CarT cell with non fusion dendritic cell. This study shows a promsing method of treating solid state tumors.

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