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Laser Incising - A Philosophical Shift: From Timber Treatment to Wood Modification
Get PDFTimber incising has been known and investigated for many years, yet remains a very diverse field. Often simplified into three main categories: mechanical incision, laser incision and bioincising, this group of technologies is commonly seen as the domain of timber preservation. To date only mechanical incising has been fully commercialised. Yet laser incision offers essential differences which mark it out as suitable for wood modification and high value products, with great aesthetic appeal and high market value. Wood modification requires near-perfect distribution of the treatment agent. This is achieved in laser incision through careful matching of incision patterns and strategies with the timber species. Building on successful collaborative research, we have demonstrated the technology application in a full scale (plank length 3m) resin modification process for both softwoods and hardwoods. In this poster we present the concept of laser incision and the reasons it is so well suited to revolutionise all fluid-based wood modification systems (e.g. chemical modifications, resin and polymer modifications) as well as other protective treatments.<br/
Confirmatory Factor Analysis of the Telugu Version of the PRIME Screen-revised (PS-R), a Tool to Screen Individuals at Clinical High-Risk for Psychosis
Get PDFThe experiences and perspectives of people with gout on urate self-monitoring
Get PDFINTRODUCTION: Gout management remains suboptimal despite safe and effective urate-lowering therapy. Self-monitoring of urate may improve gout management, however, the acceptability of urate self-monitoring by people with gout is unknown. The aim of this study was to explore the experiences of urate self-monitoring in people with gout.METHODS: Semistructured interviews were conducted with people taking urate-lowering therapy (N = 30) in a 12-month trial of urate self-monitoring in rural and urban Australia. Interviews covered the experience of monitoring and its effect on gout self-management. Deidentified transcripts were analysed thematically.RESULTS: Participants valued the ability to self-monitor and gain more understanding of urate control compared with the annual monitoring ordered by their doctors. Participants indicated that self-monitoring at home was easy, convenient and informed gout self-management behaviours such as dietary modifications, hydration, exercise and medication routines. Many participants self-monitored to understand urate concentration changes in response to feeling a gout flare was imminent or whether their behaviours, for example, alcohol intake, increased the risk of a gout flare. Urate concentrations were shared with doctors mainly when they were above target to seek management support, and this led to allopurinol dose increases in some cases.CONCLUSION: Urate self-monitoring was viewed by people with gout as convenient and useful for independent management of gout. They believed self-monitoring achieved better gout control with a less restricted lifestyle. Urate data was shared with doctors at the patient's discretion and helped inform clinical decisions, such as allopurinol dose changes. Further research on implementing urate self-monitoring in routine care would enable an evaluation of its impact on medication adherence and clinical outcomes, as well as inform gout management guidelines.PATIENT OR PUBLIC CONTRIBUTION: One person with gout, who was not a participant, was involved in the study design by providing feedback and pilot testing the semistructured interview guide. In response to their feedback, subsequent modifications to the interview guide were made to improve the understandability of the questions from a patient perspective. No additional questions were suggested.</p
Archwilio profiadau bywyd ac anghenion unigolion sy’n rhoi gofal yng Ngogledd Cymru er mwyn datblygu gwybodaeth a dealltwriaeth o ystyron gwahanol weithgareddau gofalu a’u heffaith ar hunaniaeth unigolion sy’n rhoi gofal.
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Understanding the Influence of Wood Species on Resin Modification and Property Enhancement in Resin modified Wood.
Get PDFIdentification of DNA repair factors which show a synthetic genetic interaction with MRE11 inhibition
Get PDFA maturational frequency discrimination deficit may explain developmental language disorder
Get PDFAuditory perceptual deficits are widely observed among children with developmental language disorder (DLD). Yet the nature of these deficits and the extent to which they explain speech and language problems remain controversial. In this study, we hypothesise that disruption to the maturation of the basilar membrane may impede the optimisation of the auditory pathway from brainstem to cortex, curtailing high-resolution frequency sensitivity and the efficient spectral decomposition and encoding of natural speech. A series of computational simulations involving deep convolutional neural networks that were trained to encode, recognise, and retrieve naturalistic speech are presented to demonstrate the strength of this account. These neural networks were built on top of biologically truthful inner ear models developed to model human cochlea function, which – in the key innovation of the current study – were scheduled to mature at different rates over time. Delaying cochlea maturation qualitatively replicated the linguistic behaviour and neurophysiology of individuals with language learning difficulties in a number of ways, resulting in: (i) delayed language acquisition profiles; (ii) lower spoken word recognition accuracy; (iii) word finding and retrieval difficulties; (iv) ‘fuzzy’ and intersecting speech encodings and signatures of immature neural optimisation; and (v) emergent working memory and attentional deficits. These simulations illustrate the many negative cascading effects that a primary maturational frequency discrimination deficit may have on early language development, and generate precise and testable hypotheses for future research into the nature and cost of auditory processing deficits in children with language learning difficulties