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The connection between school engagement and depressive symptoms in upper secondary school students
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Resilience among the individuals with a colorectal cancer diagnosis and their evaluations of the received patient counseling
No full textResponses of needle terpene concentrations and characteristics of resin canals to different warming treatments in Scots pine and Norway spruce seedlings grown in a field experiment
No full textWe studied responses of needle terpene concentrations and resin canal characteristics to warming in Scots pine (Pinus sylvestris) and Norway spruce (Picea abies) seedlings grown in a controlled field set-up in eastern Finland. Warming was simulated during the growing seasons using infrared heaters that increased air temperature in study 1 (2016–2019) by 1 °C and in study 2 (2019–2020) by 2 and 4 °C, compared to ambient conditions. Terpenes were sampled in study 1 from non-matured current year and matured previous year needles in June 2019, and study 2 from mature current year needles in August 2020. In study 1, we also studied resin canal anatomy. We found that 1 °C elevation of temperature caused two-fold increase in concentrations of total terpenes, oxygenated monoterpenes, and sesquiterpenes of non-matured current year needles of Norway spruce. Further, it caused 1.3–1.8-fold increases in sesquiterpene concentrations both in unmatured and matured needles of Scots pine. It also decreased resin canal diameter of mature needles in Norway spruce. In study 2, the stronger warming treatments did not affect terpene concentrations of matured current year needles in either species. Based on our findings, even minor elevation of temperature may affect terpene concentrations of non-mature needles in boreal conifers
[PART 4] Look what you made me do: conformational shifts in steroid hormone receptors induced by endocrine-disrupting chemicals.
No full textMD simulations of different conformations ofERalpha with endoxifen. Details are available in the respective publication. 1318- ERalpha 3ERT endoxifen 13A3 OPLS4 Maestro2024.11319- ERalpha 1GWR endoxifen 13A3 OPLS4 Maestro2024.1 METADYNAMICS: 1160- human GR receptor DEX PDB 1M2Z T3A3 TIP3P OPLS4 1161- human ERa betaEstradiol PDB 1GWR T3A3 TIP3P OPLS4 1177- human GR ANTAGONIST 3H52 PDB 1M2Z T3A3 TIP3P OPLS4 (Antagonist in the ago-structure) 1319- ERalpha 1GWR endoxifen 13A3 OPLS4 (Antagonist in the ago-structure
Every move counts? : associations of active commuting and leisure-time physical activity with mental health and perceived cognitive function among Finnish adolescents and employed adults
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