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[PART 1] Design, Synthesis, and Development of dual CatL-Main Pro Inhibitors of SARS-CoV-2
MD simulations of Mpro with respective inhibitors with different mutation backgrounds. For more details please check the respective JMC publication. 1291- Mpro 7TE0_WT_nirma 13A3 OPLS41292- Mpro 8H82_E166V_nirma 13A3 OPLS41293- Mpro 8H7W_S144M_nirma 13A3 OPLS4 (originally 8H7W is S144A)1294- Mpro WT FP237-xtal bound to 8n/FP238 non cov 13A3 OPLS41295- Mpro WT FP237-xtal bound to 8n/FP238 covbound 13A3 OPLS41296- Mpro E166V FP237-xtal bound to 8n/FP238 non cov 13A3 OPLS41297- Mpro E166V FP237-xtal bound to 8n/FP238 covbound 13A3 OPLS41298- Mpro S144M FP237-xtal bound to 8n/FP238 non cov 13A3 OPLS41299- Mpro S144M FP237-xtal bound to 8n/FP238 covbound 13A3 OPLS41300- Mpro 7TE0_WT_nirma (NON COV) 13A3 OPLS4 (200ns/day) - 10x200ns (gpu48_cov
Online-alustasopimusten kilpailua rajoittavat Most Favoured Nation -lausekkeet Euroopan unionin kilpailuoikeuden näkökulmasta
Finnish-Russian dual citizenship in the media texts of Helsingin Sanomat in 2014-2024 from the perspective of securitization
Channel Behavior in Platform Retailing - With Reference to Multi-sided Marketplaces in Sri Lanka
Digital platforms
Digital platforms are mediated by technology, enabling interaction between user groups and facilitating the accomplishment of tasks. This mediation is made possible by digital infrastructures, such as the internet and mobile networks, which link objects, individuals, and organizations that both consume and generate data. Interaction on digital platforms can enable three types of tasks: innovation, transaction, or both. Digital innovation platforms allow third-party companies, such as software developers, to create complementary products or services. Digital transaction platforms facilitate exchanges between organizations, entities, and individuals. Additionally, there are platforms that enable both transaction and innovation tasks, known as digital integrated or digital hybrid platforms. Digital platforms have been studied from both technical and non-technical perspectives. Although digital platforms provide a variety of benefits, they also have a dark side. Dark sides of digital platforms are addressed in terms of surveillance and security and monopolies, for example
Primary School Teachers’ Competence in Promoting Mental Health – A Systematic Mixed-Methods Review
How do classroom teachers concretely implement positive pedagogy in their work in light of the PERMA theory?
Capability approach
Considered a crucial issue for the successful performance of firms and the entire economy, the concept of innovation capability has received increasing attention in research about innovation and innovation management. Literature has identified several dimensions of innovation capability, but the focus of research has mostly remained at the level of individual companies. This entry introduces the Capability Approach (CA), developed by Amartya Sen and Martha Nussbaum, as a way to bridge the gap between micro and macro levels of analysis. CA is a general framework focusing on identifying and evaluating factors that impact people's well-being and their ability to function in society. CA has opened up interesting perspectives for research, which partly challenge and partly complement previous economic- and technology-focused viewpoints on innovation. The entry argues for a need for innovation management literature to engage in deeper critical analysis and exploration of the interrelationships between innovation, well-being, and development