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The Life, Teaching, Death, and Resurrection of Jesus of Nazareth and Some Implications [Lecture Notes]
Get PDFLecture notes on a series of talks by Scott G. Sinclair\u27s on his version of the Historical Jesus
The Ketogenic Diet: Its Effectiveness as an Adjuvant Therapy for Cancer
Get PDFThis paper explores a total of six research studies and will contain a literature review and proposal for further study regarding the effectiveness of the ketogenic diet as an adjuvant cancer therapy. Each study addresses a variety of different factors involved in KD implementation, ranging from effects on body composition and lipid profiles, to self-proclaimed quality of life, to tumor expression and progression under a KD regime. Ultimately, each were divided into three separate categories depending on the aspects of research that were covered. Two studies, by Hagihara et.al and Jansen and Walach respectively, discuss the potential benefits of KD in cancer patients, while two additional studies by Sremanokova et.al and Klement et.al address concerns regarding the implementation of KD in cancer populations. The final category and studies by Yang et.al and Erickson et.al claim a lack of significance in the use of KD in clinical practice, and examine why this is the case. The major findings and limitations of each study will be discussed in detail, alongside theme comparisons between studies. Based on the findings discussed, the new research question in the proposal for further study will address the anti-tumor effects of KD on glioblastoma specifically. The study will be a longitudinal mixed method design and will only involve participants diagnosed with glioblastomas. The data obtained through conducted interviews and surveys will be analyzed through audio recordings, written assessment scales, and questionnaires completed by participants. Additional lab work will be done for the statistical analysis portion and will observe changes in blood ketone levels, TKTL1 expression, and cfDNA blood levels respectively. The final portion will discuss the consensus between both the literature review and proposal for further study, which is that KD shows promise as an adjuvant therapy in cancer populations
StarSung: A Timeslip Novel
No full textStarSung is an ambitious timeslip speculative fiction novel, slipping back and forth
between the present and ancient times. Several modern women independently experience an out- of-time incident, feeling as if they had just barely survived a genocidal event in the distant past.
The unifying agent of StarSung is a mysterious music score. The novel begins at a Christmas concert for SETI scientists, where a string quartet premiers newly transcribed music, Promptu Familiaris by Anonymous. During the performance, the main character Marian, a viola superstar, experiences the first timeslip, finding herself briefly in the body of a young girl witnessing a terrifying attack in a burning cathedral. Too shaken to play her exquisite viola, Grif, she and her manager and best friend cellist Julian, work to unravel her vivid vision. Marian’s description seems to recount an actual event, a Medieval massacre thought to have extinguished an ancient tribe. Yet Marian’s girl survived. A recording of the concert is leaked on the college DJ circuit, prompting a few other women to experience their own timeslip, one to ancient Egypt, another to Roman Gaul, a third to pre-contact North America, a fourth to the Qin Empire in China. They follow the music back to Marian and work to unravel the mystery together. With Julian’s research, it emerges that the consciousness of the only survivor in a mitochondrial genetic lineage had somehow slipped into each modern woman and released her unique inheritance. How does this otherworldly music activate a memory from the past at a pivotal point in history? Why were these last survivors evoked now? What is their mission together? What is the true message of the StarSung music
Global Developments in Social Prescribing
Get PDFSocial prescribing is an approach that aims to improve health and well-being. It connects individuals to non-clinical services and supports that address social needs, such as those related to loneliness, housing instability and mental health. At the person level, social prescribing can give individuals the knowledge, skills, motivation and confidence to manage their own health and well-being. At the society level, it can facilitate greater collaboration across health, social, and community sectors to promote integrated care and move beyond the traditional biomedical model of health. While the term social prescribing was first popularised in the UK, this practice has become more prevalent and widely publicised internationally over the last decade. This paper aims to illuminate the ways social prescribing has been conceptualised and implemented across 17 countries in Europe, Asia, Australia and North America. We draw from the ‘Beyond the Building Blocks’ framework to describe the essential inputs for adopting social prescribing into policy and practice, related to service delivery; social determinants and household production of health; workforce; leadership and governance; financing, community organisations and societal partnerships; health technology; and information, learning and accountability. Cross-cutting lessons can inform country and regional efforts to tailor social prescribing models to best support local needs
One Face, Many Roles: A Dominican Journey from Student to Administrator
Get PDFLearn the growth and development of a Dominican University alumnus, former staff member, and Vice President for Student Affairs and Enrollment Management Paul Raccanello. This discussion centers Pauls several decades of engagement and experiences at Dominican University of California.https://scholar.dominican.edu/heritage-and-history-podcasts/1024/thumbnail.jp
Without Local Newspapers, Can We Save Our Democracy? An Analysis of Political Culture, Voter Turnout, and Civic Engagement
Get PDFSince the 1830s, newspapers have been accessible to all members of the public in the United States regardless of socio-economic status. Newspapers are important political information providers. Local journalists provide invaluable expertise for the community they serve about community-level problems, local elections, and help hold government accountable. If news organizations cannot afford to sustain a local newspaper and its staff, the result is a news desert for the community. While recent research has examined the decline of local newspapers, little has been done on how the decline of local newspapers affects civic engagement and voter turnout across the United States. To what extent do local newspapers contribute to civic engagement? Using Daniel Elazar’s (1966) typology of a state’s political culture, this thesis hypothesizes that moralistic states have fewer news deserts, higher voter turnout, and higher civic engagement than individualistic and traditionalistic states. This thesis did not find a clear distinction of moralistic states being the highest in voter turnout, in civic engagement, and lower in news desert concentration, but it appears that moralistic states have higher voter turnout in the 2014 midterm election across the board and have news deserts growing at the slowest rate compared to the individualistic and traditionalistic typologies. The health of our democratic republic requires civic engagement, and people need access to quality information to participate and cast their ballots
Characterizing the Natural History of Liver Pathology in the Alpha 1 Antitrypsin Deficiency Mouse Model
No full textAlpha 1 Antitrypsin Deficiency (A1ATD) is a rare, debilitating genetic disorder where the body cannot produce adequate amounts of A1AT protein. A1AT is predominately made in the liver and is responsible for inactivating neutrophil elastase (an anti-microbial protease) in the lungs after an immune response. Interestingly, A1AT deficiency is associated with liver dysfunction because the mutated, mis-folded z-form of the protein (zA1AT) accumulates in liver tissue, resulting in jaundice, neonatal hepatitis, cirrhosis, and hepatocellular carcinoma. A1ATD is one of the most common genetic cause of liver disease in the pediatric population, where 10% of newborns with this deficiency present with notable liver damage. To address this disorder, researchers have utilized genetically modified rodent models, including a transgenic mouse model of A1AT liver disease that expresses the human zA1AT. However, a well-defined natural history of this model measuring age-dependent expression of pathological biomarkers is currently incomplete and could provide additional insights on this model’s relevancy. Thus, the purpose of this dissertational work is to characterize the age-dependent development of liver pathology in the transgenic zA1AT mouse model. Our results indicate that insoluble zA1AT polymers accumulate as early as 4 weeks of age in these mice and increase by 5% bi- weekly until 36 weeks of age, when there is an abrupt drop in levels, most likely due to increasing liver stress. Sirius Red signal, indicative of liver fibrosis, is also elevated at 36 and 52 weeks of age. IBA-1, a marker of liver Kupffer cells, is only increased at 13 weeks of age. We also identified a soluble form of zA1AT, which likely precedes insoluble polymer formation. Together, these results begin to characterize, in detail, the liver disease progression of this mouse model and can help researchers strategize on treatment paradigms that focus on early prevention of polymer formation, or treatment later in life to model disease reversal paradigms
Comparing the Effectiveness of Methods Meant to Reduce Perineal Laceration Rates
Get PDFBackground
Perineal lacerations are a common occurrence in childbirth- with tears occurring in 53-79% of women. Trauma to the perineum is classified into 4 categories, with each class increasing in severity. Severe perineal lacerations have long term consequences for the women who experience them.
Objectives
To compare the effectiveness of methods which aim to reduce the rate and severity of perineal lacerations, including: hands on vs hands off technique, slow and controlled birth, use of lubrication, perineal massage, etc.
Summary of Findings
The literature review suggests that it is critical to employ methods to reduce laceration incidence and severity as the consequences of lacerations- specifically third and fourth degree lacerations- include anal incontinence, weaker pelvic floor muscles, perineal pain, and poorer sexual function. Evidence suggests that intact perineum incidence increases with the following techniques: use of a warm compress, perineal massage, use of a perineal protection device, breathing the head out, and employing a kneeling or lateral position for the second stage. Mixed evidence was found on the use of a hands on technique to support the perineum.
Proposal
As evidenced by this literature review, mixed results were found on the use of a hands on vs hands off techniques in protection of the perineum. To form a consensus on the benefits or harm of this practice, additional randomized controlled trials should be conducted
Best Practices for the Prevention and Treatment of Microcytic Hypochromic Anemia in Infancy
Get PDFBackground: Microcytic hypochromic anemia is the most common nutritional deficiency in the world. This type of anemia is commonly found during infancy due to the lack of iron-fortified foods after six months of age. The effects linked to this deficiency can cause developmental delays and behavioral disturbances in infants if not treated immediately. Therefore, it is important for nurses to find the best practices to prevent microcytic hypochromic anemia to decrease its prevalence in infancy.
Objective: To find the best nursing practices for the prevention and treatment of microcytic hypochromic anemia in infancy.
Methods: This research will utilize a literature review relating to preventative measures for microcytic hypochromic anemia in infants.
Findings: The preventative measures for this anemia includes dietary prevention, proper breastfeeding, parental knowledge, and delayed cord clamping. It is important for health care professionals, especially nurses, to give appropriate education on these measures to parents and caregivers in order to decrease the incidence of microcytic hypochromic anemia in infants.
Proposal: A quantitative quasi-experimental study will be proposed in order to find the best practices for nurses to prevent and treat microcytic hypochromic anemia during infancy.
Keywords: microcytic hypochromic anemia, iron deficiency anemia, infancy, treatment, preventio
Doodling as Self-Expression: Building Self-Efficacy in Normally Functioning Adults
Get PDFWhile previous studies identify doodling as a useful educational tool, this study sought to determine if doodling can build creative or emotional self-efficacy. Self-efficacy is an individual’s belief in their own capacity to express behaviors necessary to attain specific performance goals. The current study also sought to determine if doodling can be a form of self-care. Research collected was quantitative and qualitative using surveys to measure both creative and emotional self-efficacy along with a doodling activity. Ten participants were recruited through convenience sampling on social media and were included in the study after meeting the inclusion criteria of identifying themselves as a normally functioning adult. Individual times spent on doodling ranged from thirty minutes to three hours. The study took place during the Covid-19 pandemic which impacted the ability to recruit volunteer participants. The researcher collected data from the Emotional Self-Efficacy Scale (ESES) and Creative Self-Efficacy Scale (CSES). The results from this study support the use of doodling in art therapy as well as its effect on an individual’s self-expression and self-efficacy. The research also explores the use of doodling as a form of self-care. Recommendations for future research include expanding the population size and variety, as well as having a facilitator present to guide and witness the process