IRIS UNIME
Not a member yet
103940 research outputs found
Sort by
Artaud, Stratos e la Voce all’inverso
No full textIl testo verte sull’incontro ideale tra Antonin Artaud e Demetrio Stratos, entrambi impegnati in una radicale ricerca sulla voce come ritorno alla dimensione originaria del linguaggio, pre-logica e pre-rappresentativa. Artaud, nella fase finale della sua vita, concepisce la voce come forza magica capace di oltrepassare la parola discorsiva e di recuperare un contatto diretto con la vita; Stratos, performer d’avanguardia, ne raccoglie l’eredità spingendo la voce ai limiti del corpo, come suono puro e carnale. La loro convergenza emerge emblematicamente nella lettura di Stratos di “Per farla finita col giudizio di dio”, dove la parola diventa voce-corpo, materia e vibrazione, mostrando una delle incarnazioni della libertà nuova a cui allude la danza al rovescio di Artaud
«Tornato dalla guerra che era guerra». D’Arrigo e il tempo del ritorno
No full textIn «Horcynus Orca» Stefano D’Arrigo rappresenta il tempo bloccato e discontinuo del reduce mettendo al centro del romanzo il «microcosmo della persona» come punto focale sospeso tra natura e storia, tra contingenza e simbolo, tra sprofondamento psichico nell’immediato e ricostruzione della «presenza individuale» messa a rischio dall’urto traumatico di eventi bellici luttuosi. In tale costruzione assume un’importanza decisiva il riemergere casuale e involontario di ricordi dell’insurrezione popolare che aveva liberato Napoli dall’occupazione nazifascista a fine settembre 1943
Esercizi filologici sulla Poetica di Aristotele: il laboratorio cinquecentesco
No full textIl saggio affronta una pagina dell'ampia fortuna della "Poetica" aristotelica nel Cinquecento. Indaga in particolare le modalità di approccio al testo greco da parte di un gruppo di dotti umanisti che affrontano l'opera dello Stagirita di volta in volta sotto il profilo testuale, esegetico e critico-interpretativo, offrendo una serie di esempi tesi a illustrare attraverso l'analisi di singoli passi il metodo di indagine sulla "Poetica"
O-EQS-6 Interaction of O-phosphoryl ligands with Cu2+ and Zn2+ in aqueous solution: a speciation study
No full textO-derivatization of natural tropolone and β-thujaplicin leading to effective inhibitors of human carbonic anhydrases IX and XII
No full text: Herein we report the chemical derivatization of the naturally occurring Tropolone (TRP) and its related compound β-Thujaplicin (β-TJP) as well as their in vitro assessment for inhibition of the physio/pathologically relevant hCAs isoforms I, II, VA; VII, IX and XII to obtain a first set of inhibition data useful for driving selected derivatives towards appropriate biomedical exploitation. The selected compound 17β was characterized for its chemical stability and assessed for its antiproliferative activity on a multiple myeloma model and showed potent pro-apoptotic features jointly with a safe toxicity profile on healthy cells. The binding mode of β-TJP within the hCA II was assessed by means of X-ray crystallography of the hCA II/β-TJP complex and showed almost complete superposition with the hCA II/TRP adduct reported in the literature. The data produced were used to elaborate a binding prediction model of such compounds on the hCAs VA, IX, and XII which are directly connected to important diseases. Overall, the achievements reported in this work are in the sustainment of the exploitation of naturally occurring troponoloid-based structures for biomedical purposes and thus contribute to the field in extending the variety of available chemical features
Characterization of Capparis spinosa oil by cis-vaccenic triglyceride synthesis
No full textThe objective of the present work was to conduct an in-depth evaluation of Capparis spinosa seed oil,
with particular attention to the chemical characterization and determination of cis-vaccenic acid. This
omega-7 monounsaturated fatty acid is known for its biological and nutritional properties, including
its potential effect on lipid metabolism and cardiovascular health benefits.
The chemical characterization of caper oil was carried out by NMR spectroscopy, which allowed the
lipid composition of the oil to be described in detail and compared with that of olive oil.
The data collected by 13C-NMR spectroscopy were analyzed using the MARA (Method for
Automatic Resonance Assignment) method [1].
Another phase of the study was the chemical synthesis of the cis-vaccenic triglyceride, carried out to
obtain a stable and precise chemical reference, essential to confirm the attribution of the signals
detected in the 13C-NMR analysis and to allow the identification and accurate quantification of the
compound in natural samples. 13C-NMR analysis highlighted significant differences in lipid
composition between Capparis spinosa oil (CSO) and extra virgin olive oil (EVOO). The cis-vaccenic
acid signals, located at approximately 129.8 and 129.9 ppm, corresponding to carbon 11 and 12, were
particularly more intense in CSO than in EVOO.
The MARA methodology allowed an accurate quantitative characterization. In CSO, cis-vaccenic
acid constitutes 35-40% of the lipid composition, compared to 3% in EVOO.
Analysis of the previously synthesized vaccenic acid triglyceride confirmed the assignment of signals
between 129.9 ppm and 129.8 ppm. Spectroscopic confirmation of the product identity was essential
not only to validate the synthetic process, but also to guarantee the suitability of the compound for
future biological studies, ensuring its quality and structural conformity.
In summary, the study aims to demonstrate how Capparis spinosa oil can be valorized through
advanced chemical analysis, highlighting its nutritional qualities and potential commercial
applications. This work aims to significantly contribute to the scientific knowledge of a highly
valuable natural product, opening new opportunities for its inclusion in high-quality production
chains.[2
Phytoremediation of heavy metals by microalgae: a mini review
No full textThere are five heavy metals, namely arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb) and mercury (Hg), which are carcinogenic and pose health risks, even in trace amounts. Due to their several benefits, microalgae are increasingly being used in phytoremediation to remove heavy metals, due to their abundant availability, low cost, and excellent metal removal efficiency. Using microalgae as soil remediation and biosorption agents for these toxic heavy metals, this review paper aims to report recent advances and mechanisms. The use of non-living biomass as biosorbents and the tolerance and response of different microalgae strains to heavy metals are discussed along with their bioaccumulation capability. Additionally, microalgae are explored as a bioremediation method for heavy metals. Overall, this review provides useful insights that can be applied to the development of efficient and commercially viable technology for heavy metal bioremediation using microalgae
Dissimilar Welded Joints and Sustainable Materials for Ship Structures
No full textShipbuilding and offshore structures employ a wide range of metallic materials, from standard and high-strength steels to non-ferrous aluminium and titanium alloys. While welding remains the dominant joining method, the reliable joining of dissimilar metals still presents significant challenges. The explosion welding (EXW) technique has been increasingly adopted over traditional methods for joining dissimilar metallic materials, due to the advantage of avoiding constraints related to metallurgical incompatibility. The EXW is a solid-state joining process in which an explosive detonation provides the energy required to drive two metal surfaces into high-velocity collision, producing a metallurgical bond. This process results in partial melting at the wavy interface and the formation of intermetallic properties, which can lead to cracking when exposed to dynamic loading. A well-established application in shipbuilding is the connection of an aluminium superstructure to steel decks. This study evaluates the mechanical behaviour of aluminium–steel explosion-welded joints for ship structures. The examined joints comprise ASTM A516 Gr55 structural steel, clad by explosion welding with AA5086 aluminium alloy using an intermediate layer of AA1050 commercially pure aluminium. Tensile tests were carried out using full-field techniques, such as digital image correlation (DIC) and infrared thermography (IRT)
Ideal Extensions of Free Commutative Monoids
No full textWe introduce a new family of monoids, which we call Baeth monoids. Every Baeth
monoid is an ideal extension of a free commutative monoid. For a Baeth monoid S we
study its set of atoms and Betti elements, which allows us to show that the catenary
degree of S is at most four and that the set of lengths of any element in S is an interval. We also give bounds for the ω-primality of any ideal extension of a free commutative monoid. For ideal extensions S of Nd , with d a positive integer, we show that ω(S) is finite if and only if S has finitely many gaps
Noninvasive Grading of Liver Fibrosis Based on Texture Analysis From MRI-Derived Radiomics
No full textGiven the increasing global prevalence of metabolic syndrome, this study aimed to assess the potential of MRI-derived radiomics in noninvasively grading fibrosis. The study included 79 prospectively enrolled participants who had undergone MRE due to known or suspected liver disease between November 2022 and September 2023. Among them, 48 patients were diagnosed with histopathologically confirmed liver fibrosis. A total of 107 radiomic features per patient were extracted from MRI imaging. The dataset was then divided into training and test sets for model development and validation. Stepwise feature reduction was employed to identify the most relevant features and subsequently used to train a gradient-boosted tree model. The gradient-boosted tree model, trained on the training cohort with identified radiomic features to differentiate fibrosis grades, exhibited good performances, achieving AUC values from 0.997 to 0.998. In the independent test cohort of 24 patients, the radiomics model demonstrated AUC values ranging from 0.617 to 0.830, with the highest AUC of 0.830 (95% CI 0.520–0.830) for classifying fibrosis grade 2. Incorporating ADC values did not improve the model's performance. In conclusion, our study emphasizes the significant promise of using radiomics analysis on MRI images for noninvasively staging liver fibrosis. This method provides valuable insights into tissue characteristics and patterns, enabling a retrospective liver fibrosis severity assessment from nondedicated MRI scans