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Conservation social science: Understanding and integrating human dimensions to improve conservation
No full textAbstractIt has long been claimed that a better understanding of human or social dimensions of environmental issues will improve conservation. The social sciences are one important means through which researchers and practitioners can attain that better understanding. Yet, a lack of awareness of the scope and uncertainty about the purpose of the conservation social sciences impedes the conservation community's effective engagement with the human dimensions. This paper examines the scope and purpose of eighteen subfields of classic, interdisciplinary and applied conservation social sciences and articulates ten distinct contributions that the social sciences can make to understanding and improving conservation. In brief, the conservation social sciences can be valuable to conservation for descriptive, diagnostic, disruptive, reflexive, generative, innovative, or instrumental reasons. This review and supporting materials provides a succinct yet comprehensive reference for conservation scientists and practitioners. We contend that the social sciences can help facilitate conservation policies, actions and outcomes that are more legitimate, salient, robust and effective
Elemental characterization of Japanese green tea leaves and tea infusion residue by neutron-induced prompt and delayed gamma-ray analysis
No full textAbstractThe determination of mineral compositions of Japanese green tea leaves was carried out using a combination of PGA (neutron-induced prompt gamma-ray analysis) and INAA (instrumental neutron activation analysis). Due to the nondestructive, multi-element analytical capability and minimal sample preparation, these techniques can easily be used to determine a wide range of elemental contents (from 7.4% of H to 7.1ng/g of Sc) in tea leaves. The extraction efficiencies of the elements in tea infusion were evaluated by comparing average elemental concentrations of the tea leaves before and after infusion, which show that Cl (93%), Br (80%), K (71%), Rb (66%), Cs (60%), Na (59%) and Co (51%) are highly extracted, whereas Fe (9%), La (7%) and Mn (5%) are poorly extracted by a 6min hot water infusion process. Although K has a high content in green tea leaves with high extraction efficiency, as much as seven cups (250mL each cup) of green tea infusion need to be consumed to get a source of 10% daily value of this mineral
The impact of global climate change on water quantity and quality: A system dynamics approach to the US–Mexican transborder region
No full textAbstractThe potential impacts of Global Climate Change (GCC) in zones where water is scarce, such as along the US–Mexico border is, and will continue to be, a key concern for the future sustainability of humanity. This paper estimates the variation in quality/quantity water due to climate change and assesses its impact on community development in the US–Mexico border region of the Rio Grande/Rio Bravo Water Basin. To estimate variation in different water quality parameters, we use a conservative model with most probable scenarios for temperature/precipitation produced by the International Panel on Climate Change. We propose a system dynamics model to understand the complex interaction of factors governing the quantity/quality of water and their effects on social and economic conditions. The model simulates, for a 70-year period, policies and decisions that have the potential to improve conditions and prevent risks that may lead to social unrest and hinder economic development
Secrecy and absence in the residue of covert drone strikes
No full textAbstractBy focusing on the materials and practices that prosecute drone warfare, critical scholarship has emphasised the internal state rationalisation of this violence, while positioning secrecy and absence as barriers to research. This neglects the public existence of covert U.S. drone strikes through the rumours and debris they leave behind, and the consequences for legitimisation. This article argues that by signifying the possible use of covertness, the public residue of unseen strikes materialises spaces of suspected secrecy. This secrecy frames seemingly arbitrary traces of violence as significant in having not been secreted by the state, and similarly highlights the absence in these spaces of clear markers of particular people and objects, including casualties. Drawing on colonial historiography, the article conceptualises this dynamic as producing implicit significations or intimations, unverifiable ideas from absences, which can undermine rationalisations of drone violence. The article examines the political consequences of these allusions through an historical affiliation with lynching practice. In both cases, traces of unseen violence represent the practice as distanced and confounding, prompting a focus on the struggle to comprehend. Intimations from spaces of residue position strikes as too ephemeral and materially insubstantial to understand. Unlike the operating procedures of drone warfare, then, these traces do not dehumanise targets. Rather, they narrow witnesses' ethical orientation towards these events and casualties, by prompting concern with intangibility rather than the infliction of violence itself. A political response to covert strikes must go beyond 'filling in' absences and address how absence gains meaning in implicit, inconspicuous ways
Impact of schizophrenia on anterior and posterior hippocampus during memory for complex scenes
No full textAbstractObjectivesHippocampal dysfunction has been proposed as a mechanism for memory deficits in schizophrenia. Available evidence suggests that the anterior and posterior hippocampus could be differentially affected. Accordingly, we used fMRI to test the hypothesis that activity in posterior hippocampus is disproportionately reduced in schizophrenia, particularly during spatial memory retrieval.Methods26 healthy participants and 24 patients with schizophrenia from the UC Davis Early Psychosis Program were studied while fMRI was acquired on a 3 Tesla Siemens scanner. During encoding, participants were oriented to critical items through questions about item features (e.g., “Does the lamp have a square shade?”) or spatial location (e.g., “Is the lamp on the table next to the couch?”). At test, participants determined whether scenes were changed or unchanged. fMRI analyses contrasted activation in a priori regions of interest (ROI) in anterior and posterior hippocampus during correct recognition of item changes and spatial changes.ResultsAs predicted, patients with schizophrenia exhibited reduced activation in the posterior hippocampus during detection of spatial changes but not during detection of item changes. Unexpectedly, patients exhibited increased activation of anterior hippocampus during detection of item changes. Whole brain analyses revealed reduced fronto-parietal and striatal activation in patients for spatial but not for item change trials.ConclusionsResults suggest a gradient of hippocampal dysfunction in which posterior hippocampus – which is necessary for processing fine-grained spatial relationships – is underactive, and anterior hippocampus – which may process context more globally - is overactive
Data on the densification during sintering of binder jet printed samples made from water- and gas-atomized alloy 625 powders
No full textAbstractBinder jet printing (BJP) is a metal additive manufacturing method that manufactures parts with complex geometry by depositing powder layer-by-layer, selectively joining particles in each layer with a polymeric binder and finally curing the binder. After the printing process, the parts still in the powder bed must be sintered to achieve full densification (A. Mostafaei, Y. Behnamian, Y.L. Krimer, E.L. Stevens, J.L. Luo, M. Chmielus, 2016; A. Mostafaei, E. Stevens, E. Hughes, S. Biery, C. Hilla, M. Chmielus, 2016; A. Mostafaei, Y. Behnamian, Y.L. Krimer, E.L. Stevens, J.L. Luo, M. Chmielus, 2016) [1–3]. The collected data presents the characterization of the as-received gas- and water-atomized alloy 625 powders, BJP processing parameters and density of the sintered samples. The effect of sintering temperatures on the microstructure and the relative density of binder jet printed parts made from differently atomized nickel-based superalloy 625 powders are briefly compared in this paper. Detailed data can be found in the original published papers by authors in (A. Mostafaei, J. Toman, E.L. Stevens, E.T. Hughes, Y.L. Krimer, M. Chmielus, 2017) [4]
Hepatitis C virus infection, and neurological and psychiatric disorders – A review
No full textAbstractAn association between hepatitis C virus infection and neuropsychiatric symptoms has been proposed for some years. A variety of studies have been undertaken to assess the nature and severity of these symptoms, which range from fatigue and depression to defects in attention and verbal reasoning. There is evidence of mild neurocognitive impairment in some patients with HCV infection, which is not fully attributable to liver dysfunction or psychosocial factors. Further evidence of a biological cerebral effect has arisen from studies using magnetic resonance spectroscopy; metabolic abnormalities correlate with cognitive dysfunction and resemble the patterns of neuroinflammation that have been described in HIV infection. Recent research has suggested that, in common with HIV infection, HCV may cross the blood brain barrier leading to neuroinflammation. Brain microvascular endothelial cells, astrocytes and microglia may be minor replication sites for HCV. Importantly, patient reported outcomes improve following successful antiviral therapy. Further research is required to elucidate the molecular basis for HCV entry and replication in the brain, and to clarify implications and recommendations for treatment
Extending the analysis of electroweak precision constraints in composite Higgs models
No full textAbstractIn this paper we present a detailed analysis of the Electroweak Precision Observables (EWPO) in composite Higgs models based on the coset SO(5)/SO(4). In our study we include both the fermionic top partners and the spin-1 resonances and consider their possible interplay as well. In order to achieve calculability we use the assumptions of i) partial Ultra Violet Completion (PUVC) following [1] and, ii) absence of sizable effects from physics above the cut-off. Apart from the EWPO, we also take into account the constraints from the top quark, Z and the Higgs boson masses whenever they can be predicted in terms of the model parameters. After presenting our analytic results (often, in certain limits) and discussing their symmetry properties, we also perform detailed fits of the model parameters following the Bayesian approach. We show the posterior probability distributions of the parameters in various scenarios and provide with analytic understanding whenever possible. We find that in certain cases the EWPO allow the compositeness scale to lie well below 1 TeV. Moreover, fermionic top partners of mass around 1 TeV and spin-1 resonances of mass around 2–3 TeV are consistent with the precision data
Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas
No full textMerkel cell carcinoma (MCC) is a highly malignant neuroendocrine tumor of the skin whose molecular pathogenesis is not completely understood, despite the role that Merkel cell polyomavirus can play in 55–90% of cases. To study potential mechanisms driving this disease in clinically characterized cases, we searched for somatic mutations using whole-exome sequencing, and extrapolated our findings to study functional biomarkers reporting on the activity of the mutated pathways. Confirming previous results, Merkel cell polyomavirus-negative tumors had higher mutational loads with UV signatures and more frequent mutations in TP53 and RB compared with their Merkel cell polyomavirus-positive counterparts. Despite important genetic differences, the two Merkel cell carcinoma etiologies both exhibited nuclear accumulation of oncogenic transcription factors such as NFAT or nuclear factor of activated T cells (NFAT), P-CREB, and P-STAT3, indicating commonly deregulated pathogenic mechanisms with the potential to serve as targets for therapy. A multivariable analysis identified phosphorylated CRE-binding protein as an independent survival factor with respect to clinical variables and Merkel cell polyomavirus status in our cohort of Merkel cell carcinoma patients
A Novel Percutaneous Screw Fixation of Postero-lateral Tibial Plateau Fracture using Posterior Cruciate Ligament Reconstruction Femoral Template: Technical Note 使用後交叉韌帶重建股骨模板重建後外側脛骨平台骨折的一種新的經皮螺釘固定法:技術說明
No full textAbstractPercutaneous fixation method has been applied in Schatzker type III joint depressed-type lateral tibial plateau fracture. We report a 76-year-old man suffering from a small joint depressed-type posterolateral tibial plateau fracture with surgical reduction and fixation with a novel guidance of posterior cruciate ligament (PCL) reconstruction femoral template under X-ray and arthroscopic assistance. The concept of sequential tunnel drilling in ligament reconstruction has been applied in bone impaction tunnel creation beneath the articular step with the PCL jig. Avoidance of multiple bone guide pin drilling and accurate guide pin insertion and hence screw fixation was also achieved by use of the PCL template. As illustrated, we believe that the PCL jig is a good armamentarium and adjunct equipment to achieve a more precise minimally invasive operation in special anatomical positions such as the postero-lateral tibial plateau under careful surgical planning