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Gluon fusion and bb¯ corrections to HW+W−/HZZ production in the POWHEG-BOX
No full textAbstractThe study of the Higgs boson properties is one of the most important tasks to be accomplished in the next years, at the Large Hadron Collider (LHC) and at future colliders such as the Future Circular Collider in hadron–hadron mode (FCC-hh), the potential 100 TeV follow-up of the LHC machine. In this view the precise study of the Higgs couplings to weak gauge bosons is crucial and requires as much information as possible. After the recent calculation of the next-to-leading order QCD corrections to the production cross sections and differential distributions of a Standard Model Higgs boson in association with a pair of weak bosons, matched with parton shower in the POWHEG-BOX framework, we present the gluon fusion correction gg→HW+W−(HZZ) to the process pp→HW+W−(HZZ). This correction can be sizeable and amounts to +3% (+10%) in the HW+W− process and +5% (+18%) in the HZZ process at the LHC (FCC-hh). We also present the first study of the impact of the bottom-quark initiated channels bb¯→HW+W−/HZZ and find that they induce a significant +18% correction in the HW+W− channel at the FCC-hh. We present results on total cross sections and distributions at the LHC and at the FCC-hh
Laparoscopically assisted cervical canalization and neovaginoplasty in a woman with cervical atresia and vaginal aplasia
No full textAbstractCervical atresia is a Müllerian duct system anomaly, and it is often associated with vaginal aplasia. We report the case of a 17-year-old girl who presented with primary amenorrhea and cyclical abdominal pain, and was diagnosed with cervical atresia and vaginal aplasia that were treated laparoscopically. Laparoscopically assisted cervical canalization and neovaginoplasty were performed to relieve dysmenorrhea and allow for sexual intercourse and fertility. We did not use a bowel segment, skin, or peritoneum as a graft for the neovaginoplasty. To prevent adhesions and promote epithelialization, we used an estrogen-containing cream. Moreover, we did not use a vaginal mold. The patient is free of cervical stenosis and able to have intercourse. Long-term follow-up is necessary to ensure a future pregnancy and childbirth
Differential response of cassava genotypes to infection by cassava mosaic geminiviruses
No full textAbstractMitigation of cassava mosaic disease (CMD) focuses on the introgression of resistance imparted by the polygenic recessive (CMD1), dominant monogenic (CMD2) and CMD3 loci. The mechanism(s) of resistance they impart, however, remain unknown. Two CMD susceptible and nine CMD resistant cassava genotypes were inoculated by microparticle bombardment with infectious clones of African cassava mosaic virus Cameroon strain (ACMV-CM) and the Kenyan strain K201 of East African cassava mosaic virus (EACMV KE2 [K201]). Genotypes carrying the CMD1 (TMS 30572), CMD2 (TME 3, TME 204 and Oko-iyawo) and CMD3 (TMS 97/0505) resistance mechanisms showed high levels of resistance to ACMV-CM, with viral DNA undetectable by PCR beyond 7days post inoculation (dpi). In contrast, all genotypes initially developed severe CMD symptoms and accumulated high virus titers after inoculation with EACMV KE2 (K201). Resistant genotypes recovered to become asymptomatic by 65dpi with no detectable virus in newly formed leaves. Genotype TMS 97/2205 showed highest resistance to EACMV KE2 (K201) with <30% of inoculated plants developing symptoms followed by complete recovery by 35dpi. Deep sequencing of small RNAs confirmed production of 21–24 nt virus derived small RNAs (vsRNA) that mapped to cover the entire ACMV-CM and EACMV KE2 (K201) viral genomes in both polarities, with hotspots seen within gene coding regions. In resistant genotypes, total vsRNAs were most abundant at 20 and 35dpi but reduced significantly upon recovery from CMD. In contrast, CMD susceptible genotypes displayed abundant vsRNAs throughout the experimental period. The percentage of vsRNAs reads ranked by class size were 21nt (45%), 22 nt (28%) and 24 nt (18%) in all genotypes studied. The number of vsRNA reads directly correlated with virus titer and CMD symptoms
A simplified elastic analysis of tunnel-piled structure interaction
No full textAbstractIn urban areas, engineers often need to assess tunnelling-induced displacements of piled structures and the resulting potential for damage. This paper presents an elastic study of tunnel-pile-structure interaction through Winkler-based Two-Stage Analysis Methods (TSAMs), focusing on structural displacements resulting from tunnel excavation beneath piled frames or simple equivalent beams. Comparison of results with 3D finite element analyses shows that the simple TSAM models are able to provide a good assessment of tunnelling-induced building displacements. Parametric analyses highlight the role of tunnel-pile interaction and the superstructure (stiffness, configuration, and pile-structure connections) in the global response of the tunnel-soil-building system. In particular, the effect that key parameters have on deflection ratios and horizontal strains are investigated. Results illustrate how piled foundations increase the risk of structural damage compared to shallow foundations, whereas structural stiffness can reduce building deformations. Flexural deformations are predominately induced by tunnel excavations beneath piles whereas horizontal strains at the ground level are negligible when a continuous foundation is included. Furthermore, it is illustrated that results based on buildings modelled as equivalent beams can differ considerably compared to when they are modelled as framed structures. Simple design charts are provided to estimate horizontal strains and deflection ratio modification factors based on newly defined relative axial and bending stiffness parameters which account for the presence of the piles
Disaster response under One Health in the aftermath of Nepal earthquake, 2015
No full textAbstractUntil now, an estimate quotes that 1100 healthcare facilities were damaged and over 100,000 livestock lost in the two earthquakes that occurred in April and May of 2015 in Nepal. Threats of infectious diseases, mostly zoonoses, could affect Nepal’s economy, trade, and tourism, and reaching the targets of the United Nations Millennium Development Goals. Historically, outbreaks of infectious diseases, including zoonoses, were largely associated with the aftereffects of the earthquakes. It has been documented that zoonoses constitute 61% of all known infectious diseases. Therefore, the purpose of this communication was to examine the infectious disease outbreaks after earthquakes around the world and explore the risk assessment of the zoonoses threats reported in Nepal and highlight adopting One Health. Our summaries on reported zoonoses in Nepal have shown that parasitic zoonoses were predominant, but other infectious disease outbreaks can occur. The fragile public health infrastructure and inadequately trained public health personnel can accelerate the transmission of infections, mostly zoonoses, in the post impact phase of the earthquake in Nepal. Therefore, we believe that with the support of aid agencies, veterinarians and health professionals can team up to resolve the crisis under One Health
Predicting standard penetration test N-value from cone penetration test data using artificial neural networks
No full textAbstractStandard Penetration Test (SPT) and Cone Penetration Test (CPT) are the most frequently used field tests to estimate soil parameters for geotechnical analysis and design. Numerous soil parameters are related to the SPT N-value. In contrast, CPT is becoming more popular for site investigation and geotechnical design. Correlation of CPT data with SPT N-value is very beneficial since most of the field parameters are related to SPT N-values. A back-propagation artificial neural network (ANN) model was developed to predict the N60-value from CPT data. Data used in this study consisted of 109 CPT-SPT pairs for sand, sandy silt, and silty sand soils. The ANN model input variables are: CPT tip resistance (qc), effective vertical stress (σv′), and CPT sleeve friction (fs). A different set of SPT-CPT data was used to check the reliability of the developed ANN model. It was shown that ANN model either under-predicted the N60-value by 7–16% or over-predicted it by 7–20%. It is concluded that back-propagation neural networks is a good tool to predict N60-value from CPT data with acceptable accuracy
Effects of different levels of end-expiratory pressure on hemodynamic, respiratory mechanics and systemic stress response during laparoscopic cholecystectomy
No full textAbstractObjectiveGeneral anesthesia causes reduction of functional residual capacity. And this decrease can lead to atelectasis and intrapulmonary shunting in the lung. In this study we want to evaluate the effects of 5 and 10cmH2O PEEP levels on gas exchange, hemodynamic, respiratory mechanics and systemic stress response in laparoscopic cholecystectomy.MethodsAmerican Society of Anesthesiologist I–II physical status 43 patients scheduled for laparoscopic cholecystectomy were randomly selected to receive external PEEP of 5cmH2O (PEEP 5 group) or 10cmH2O PEEP (PEEP 10 group) during pneumoperitoneum. Basal hemodynamic parameters were recorded, and arterial blood gases (ABG) and blood sampling were done for cortisol, insulin and glucose level estimations to assess the systemic stress response before induction of anesthesia. Thirty minutes after the pneumoperitoneum, the respiratory and hemodynamic parameters were recorded again and ABG and sampling for cortisol, insulin, and glucose levels were repeated. Lastly hemodynamic parameters were recorded; ABG analysis and sampling for stress response levels were taken after 60minutes from extubation.ResultsThere were no statistical differences between the two groups about hemodynamic and respiratory parameters except mean airway pressure (Pmean). Pmean, compliance and PaO2; pH values were higher in ‘PEEP 10 group’. Also, PaCO2 values were lower in ‘PEEP 10 group’. No differences were observed between insulin and lactic acid levels in the two groups. But postoperative cortisol level was significantly lower in ‘PEEP 10 group’.ConclusionVentilation with 10cmH2O PEEP increases compliance and oxygenation, does not cause hemodynamic and respiratory complications and reduces the postoperative stress response
Testing the ‘uncanny valley’ hypothesis in semirealistic computer-animated film characters: An empirical evaluation of natural film stimuli
No full textAbstractThe uncanny valley (UV) hypothesis, which predicts that almost but not fully humanlike artificial characters elicit negative evaluations, has become increasingly influential. At the same time, the hypothesis has become associated with many computer-animated films that have aimed at high realism. In the present investigation, we tested whether semirealistic animated film characters do in fact elicit negative evaluations. Fifty-four participants were asked to evaluate five matched film excerpts from each of cartoonish, semirealistic, and human-acted films. Mixed model analyses were conducted to reduce the effects of participant and stimulus related confounds. Explicit selections made after the experiment confirmed that participants associated semirealistic film characters correctly with the UV. Semirealistic animated characters also received higher eeriness ratings than the other film characters. In particular, two semirealistic films ‘Beowulf’ and ‘The Polar Express’ were selected the most often explicitly, and ‘Beowulf’ also received higher eeriness ratings than any other film. Somewhat unexpectedly, cartoonish characters received the highest strangeness ratings and (after confound correction) the lowest likability ratings. Taken together, the present findings demonstrate that semirealistic animated film characters are more eerie than cartoonish characters or real actors, and hence provide evidence for the existence of the UV in animated film characters
Energy flows and greenhouses gases of EU (European Union) national breads using an LCA (Life Cycle Assessment) approach
No full textAbstractBread represents a staple food in many parts of the world including Europe. Depending on the region of origin and the respective cultural heritage bread is made with different ingredients and is consumed in various forms. This work consists of an environmental sustainability assessment of 21 different types of bread, representing a wide spectrum of typologies of such food consumed across the European Union, via a Life Cycle Assessment approach. The embedded energy and equivalent greenhouse gas emissions of each type of bread were estimated, from cradle to bakery gate, by considering a mass, a nutritional value and a price based functional unit. Overall, the results have highlighted the variability of the embedded energy and the equivalent GHG (greenhouse gas) emissions associated to the consumption of the 21 kinds of bread rooted in the cultural environment of 21 EU countries. When considering a functional unit of 1 kg of bread, the Cumulative Energy Demand results range from 9 MJ/kg to 32.9 MJ/kg. The Global Warming Potential indicator has a minimum value of 0.5 kgCO2eq/kg and a maximum of 6.6 kgCO2eq/kg. For a functional unit amounting to a 100 kcal provided by the consumption of bread, the Cumulative Energy Demand results vary from 0.33 MJ/100 kcal to 0.93 MJ/100 kcal whilst the Global Warming Potential indicator varies from 0.019 kgCO2eq/100 kcal to 0.135 kgCO2eq/100 kcal. For a functional unit amounting to the quantity of bread purchased with 1€ (weighted according to the purchasing price of each nation in the European Union), the Cumulative Energy Demand results vary from 1.197 MJ/€ to 3.708 MJ/€ whilst the Global Warming Potential indicator varies from 0.15 kgCO2eq/€ to 0.376 kgCO2eq/€.The study has pinpointed the importance of evaluating food, in terms of environmental sustainability, with more than one type of functional unit in order to account not only for the bread's nutritional purposes but also the need to satisfy social, cultural, hedonistic and other qualitative functions. Specifically, when using a mass based functional unit, the less impactful results involve bread types with simple recipes, based essentially on flour, yeast and water. By assessing the breads with an energy based functional unit, bread types which also contain vegetable oils and small amounts of animal based ingredients result as more carbon and energy friendly. The use of a price based functional unit indicates that the higher priced bread types, manufactured with more expensive ingredients that are produced in an environmentally efficient manner, are the more sustainable ones. Overall, for many types of bread, the energy consumption during the production phase, in particular the baking process, represents a hot spot and is dependent on the size and shape of the bread. Furthermore, the efficiency of ingredient production (in terms of material and energy use and in terms of the respective yields of each nation in the European Union), such as that of milk and flour, also influences the sustainability of the bread types