Washington Research Library Consortium - Digital Collections
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Henry James' Romantic Responses to Architecture
Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis optio
Artists' Fantasies of Women: A Study of Miro and Delvaux
Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis optio
Giorgio de Chirico's Paintings of Italian Squares as Fantasy in Art
Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis optio
Rene Magritte and Surrealism
Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis optio
The Uses of Antiquity in Florence: 1400-1435
Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis optio
Innovation in journalism through engagement design
In our quest to find ways to make journalism more interactive and engaging, the JoLT team at American University concluded that the design principles that make gaming so captivating and lucrative can be applied to the challenges facing the news industry
Gym Closed' sign at Gold's Gym
Sign posted in the window of a Gold's Gym. It reads 'GYM CLOSED. AS MANDATED BY DC GOVERNMENT. During this uncertain time, continue your fitness journey with FREE access to GOLD'S AMP (TM) our digital personal training and fitness APP. To get started, visit goldsamp.com/promo now, enter promo code MM60, and then create your new account (or use your existing Gold's Gym member App credentials for a seamless experience).' The sign features the Gold's Gym logo and the buildings and cars across the street are reflected in the window.Cataloger note: Punctuation added to description for clarity
People preparing meals at World Central Kitchen
Dreaming Out Loud DREAM Program alumni wear masks while preparing meals for seniors and homebound residents at World Central Kitchen. The meals are recipes featuring local Black foodmakers, Crissy Taylor of Taylored Taste and Kendra Hazel of Green Things Work
Signs in the window of a restaurant
Signs in the window of a restaurant that read, 'We are open now.' An illuminated 'open' sign also hangs in the window
Data-based RNA-seq simulations by binomial thinning
BMC Bioinformatics, Volume 21, Issue 1, 24 May 2020, Article number 206.Background: With the explosion in the number of methods designed to analyze bulk and single-cell RNA-seq data, there is a growing need for approaches that assess and compare these methods. The usual technique is to compare methods on data simulated according to some theoretical model. However, as real data often exhibit violations from theoretical models, this can result in unsubstantiated claims of a method's performance. Results: Rather than generate data from a theoretical model, in this paper we develop methods to add signal to real RNA-seq datasets. Since the resulting simulated data are not generated from an unrealistic theoretical model, they exhibit realistic (annoying) attributes of real data. This lets RNA-seq methods developers assess their procedures in non-ideal (model-violating) scenarios. Our procedures may be applied to both single-cell and bulk RNA-seq. We show that our simulation method results in more realistic datasets and can alter the conclusions of a differential expression analysis study. We also demonstrate our approach by comparing various factor analysis techniques on RNA-seq datasets. Conclusions: Using data simulated from a theoretical model can substantially impact the results of a study. We developed more realistic simulation techniques for RNA-seq data