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    Making territory through infrastructure: The governance of natural gas transit in Europe

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    Recent political and military events in Ukraine have brought into sharp focus concerns over the security of European gas supplies from Russia. At the same time, the creation of an infrastructural and political ‘energy union’ has become a key stated priority for the governing bodies of the European Union. Both contingencies have highlighted the 28-nation bloc’s dependence on energy sources well beyond its state boundaries, underpinned by the existence of a transnational network for the transport and distribution of natural gas. We develop a theoretical framework predicated upon assemblage and governance approaches to explore the regulatory practices and spatial features associated with this hitherto largely unexplored infrastructural realm. Qualitative evidence from interviews, policy documents and media reports is interrogated interpretively and with the aid of social network analysis techniques. The paper reveals the existence of a socio-technical assemblage for the transmission of natural gas across national boundaries emerging as a result of the erosion of decision-making power away from established state actors, and the rise of new institutional orders. While undermining the organizational arrangements that have traditionally dominated the European gas sector, these contingencies also challenge existing understandings of transnational energy governance as they apply to overland gas transit

    The influence of prior training on GPs’ attitudes to sickness absence certification post-fit note.

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    AimTo investigate the attitudes to health and work of general practitioners (GPs) with training in occupational medicine (OM) compared with non-OM trained GPs, since the introduction of the fit note.BackgroundChanges to the UK sickness certification system since 2010 and the introduction of the fit note required GPs to change their focus to what patients can do, rather than what they cannot do in relation to work. In an effort to reduce the UK sickness absence burden, GPs completion of the fit note should help to keep people in work, or assist patients to return to work as quickly as possible after a period of absence.MethodsQuestionnaire data were collected via the 7th National General Practitioner Worklife Survey.FindingsResults indicate that responses from GPs who had undertaken training in OM, and GPs having received some form of work and health training in the 12-month period before the study were associated with significantly more positive attitudes to patients’ returning to work and to the fit note. This study reveals evidence of a difference between trained and non-trained GPs in their attitude to the fit note, and to work and health generally. Further work investigating the effect of specific training in OM on the management and recognition of ill-health by GPs is recommended

    MultiElec: A MATLAB Based Application for MEA Data Analysis.

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    We present MultiElec, an open source MATLAB based application for data analysis of microelectrode array (MEA) recordings. MultiElec displays an extremely user-friendly graphic user interface (GUI) that allows the simultaneous display and analysis of voltage traces for 60 electrodes and includes functions for activation-time determination, the production of activation-time heat maps with activation time and isoline display. Furthermore, local conduction velocities are semi-automatically calculated along with their corresponding vector plots. MultiElec allows ad hoc signal suppression, enabling the user to easily and efficiently handle signal artefacts and for incomplete data sets to be analysed. Voltage traces and heat maps can be simply exported for figure production and presentation. In addition, our platform is able to produce 3D videos of signal progression over all 60 electrodes. Functions are controlled entirely by a single GUI with no need for command line input or any understanding of MATLAB code. MultiElec is open source under the terms of the GNU General Public License as published by the Free Software Foundation, version 3. Both the program and source code are available to download from http://www.cancer.manchester.ac.uk/MultiElec/

    Poly(vinylamine) microgel–dextran composite hydrogels: Characterisation; properties and pH-triggered degradation

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    The present study involves an investigation of the formation, characterisation and triggered-degradation of mixed dispersions involving cationic poly(vinylamine-co-bis(ethyl vinylamine) ether) (PVAM-BEVAME) microgel (MG) particles and partially oxidised dextran (Dexox). In this approach to colloidal hydrogel composite formation, imine bonds were formed by reaction between aldehyde groups of Dexox and the primary amine groups on the MG particles. The composite hydrogels contained MG particles that were externally cross-linked by Dexox to form an elastically effective network with high storage modulus (G′) values and low tan δ (=G″/G′, where G″ is the loss modulus) values. The G′ values for the MG–Dexox gels increased exponentially with increasing mass ratio (MR) of Dexox to MG. Interestingly, the yield strains determined from rheology also increased with MR and yield strains of up to 130% were measured. Au nanoparticles of comparable size to the Dexox chains adsorbed to the surface of the MG particles, which suggests that the pore size of the MG particles may have been smaller than that of the Dexox coils. The MG–Dexox gels were also subjected to acidic conditions to demonstrate pH-triggered gel network breakdown via imine bond cleavage. We show that new PVAM MG/aldehyde mixtures studied here for the first time form ductile and versatile colloidal gels and our new method provides a route to increasing ductility of hydrogels containing MG particles

    The Charity-Mongers of Modern Babylon: Bureaucracy, Scandal, and the Transformation of the Philanthropic Marketplace, c.1870–1912

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    This essay sheds new light on the supposedly familiar world of Victorian philanthropy by considering charity in relation to market regulation. Focusing on the “charity fraud,” we suggest that in the shaping of this exclusive and paradoxical marketplace, charities eagerly seized fraud denunciations to advertise and authenticate their legitimacy. This reflected the massive changes in the charitable world since the days of paternalist social relations and, paradoxically, illustrates the extremity of the problem facing the donating public: if one could not be entirely certain of a local charity, how could he or she discern between the national organizations that undertook fund-raising for international disasters? This contest for legitimacy and the exposure of fraud shaped a contested but oddly virtuous exchange market: by the turn of the twentieth century, charities not only published account sheets but debated them publicly, too

    Restoration of chondrocytic phenotype on a two-dimensional micropatterned surface

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    Chondrocytes within mature cartilage reside in a 3D matrix and adopt a distinctive round morphology. A vast 2D-culture surface is well-known to induce chondrocyte dedifferentiation characterized by the loss of spherical morphology and ceased expression of chondrogenic markers. Methods to restore chondrogenesis so far only occur on a certain level producing varied cell subpopulations and inferior cartilage matrix; the critical parameters, especially for the pericellular microenvironment, are still to be precisely determined. In this study, arrays of 2D circular micropatterns were designed to hold single subcultured chondrocytes with stable adhesion. The chondrocytes rounded up forming a 3D architecture; they remodeled their cytoskeleton to resemble in-situ chondrocytes and expressed collagen II instead of collagen I or fibronectin. This technique suggested that pure physical constraints can induce chondrocytic phenotype restoration on a 2D surface; it also provides a new design pathway to precisely control the microenvironment surrounding every chondrocyte therefore to unify the redifferentiation level of individual cell

    Should retail trade companies avoid recruiting maximisers?

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    Purpose – The purpose of this paper is to investigate differences in characteristics, job outcome experiences and attitudes of maximiser and satisficer decision-making style groups working in the retail trade. Design/methodology/approach – A survey of 140 participants who have accepted a job offer in the retail trade in the past six months in the USA was conducted on Amazon Mechanical Turk. The survey examined participants’ opinions and attitudes towards their present job and established which job information source(s) they had used to search for retail trade job-related information. Findings – The results show that compared to satisficers, maximisers exert more effort when searching job information, have higher uncertainty avoidance and need for cognition, and experience more post-decisional regret. In this sample, any significant differences between maximisers and satisficers in relation to job satisfaction, company commitment, and intention to quit their present job are restricted to certain groups. For recruitment information sources, while satisficers rely on their families and friends for information, maximisers are more likely to obtain job-related information from other sources such as online discussion forums. Practical implications – Even though some studies suggest that maximisers are unhappy with their choices, this research recommends that retail trade companies should not exclude maximisers from their recruitment pools. Retailers should enhance their candidate pools with both maximisers and satisficers by managing different recruitment information sources. Originality/value – Research of decision-making style in recruitment is relatively limited. This research illustrates the differences of attitudes between maximisers and satisficers towards their present retail job, and also demonstrates the preferences of maximisers and satisficers in recruitment information sources

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