Naresuan University Journal
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Use of a Continuous Wave Laser and Pockels Cell for Sensitive High-Resolution Collinear Resonance Ionization Spectroscopy
No full textConstraints on the off-shell Higgs boson signal strength in the high-mass and final states with the ATLAS detector
No full textA qualitative study of the views of adolescents on their caries risk and prevention behaviours
No full textBACKGROUND: The purpose of this study was to explore the attitudes and beliefs of adolescents towards dental caries and their use or non-use of caries prevention regimens. METHODS: Adolescents aged 16 years from four state-funded secondary schools in North West of England (n = 19). Purposive sampling strategically selected participants with characteristics to inform the study aims (gender, ethnicity, and caries status). Semi-structured interviews were transcribed verbatim and analysed using a framework approach. RESULTS: 14 codes within five overarching themes were identified: "Personal definition and understanding of oral health"; "Knowledge of oral health determinants"; "Influences on oral health care"; Reason for oral health behaviours"; and "Oral health in the future". Adolescents conceptualise oral health as the absence of oral pathology and the ability to function, which included an aesthetic component. Appearing to have healthy teeth was socially desirable and equated with positive self-image. The dominant influence over oral health behaviours was habitual practice encouraged by parents from a young age, with limited reinforcement at school or by dental practices. At this transitional age, participants recognised the increasing influence of peers over health behaviours. Self-efficacy pertained to diet modification (reduction in sugar-ingestion) and oral hygiene behaviour (tooth-brushing). A lack of understanding of caries aetiology was evident. Behaviours were mitigated by a lack of environmental support; and a desire for immediate gratification often overcame attempts at risk-reducing behaviour. CONCLUSIONS: Parents primarily influence the habitual behaviours of adolescents. With age, the external environment (availability of sugar and peers) has an increasing influence on behaviour. This suggests that to improve adolescent health, oral health promoters should engage with parents from early childhood and create supportive environments including public policy on sugar availability to encourage uptake of risk-minimising behaviours
Challenges in oil test database analysis for ageing assessment of in-service transformers
No full textRisk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 30-year semi-prospective analysis.
No full textBRCA1 and BRCA2 mutation carriers have an increased risk of contralateral breast cancer after primary breast cancer. Risk reduction strategies are discussed after assessment of risk factors for developing contralateral breast cancer. We assessed potential risk factors that could be of use in clinical practice, including the novel use of single nucleotide polymorphisms (SNP) testing. 506 BRCA1 and 505 BRCA2 mutation carriers with a diagnosis of breast cancer were observed for up to 30 years. The risk of a contralateral breast cancer is approximately 2-3 % per year, remaining constant for at least 20 years. This was similar in both BRCA1 and BRCA2 carriers. Initial breast cancer before age 40-years was a significant risk factor, which was more pronounced in BRCA1 patients. The effect of risk-reducing oophorectomy on contralateral breast cancer risk may be overestimated because of bias. No significant association was found between overall breast cancer risk SNP score and contralateral breast cancer development. Young mutation carriers, particularly those with BRCA1 mutations, who develop breast cancer have a significantly higher risk of developing contralateral breast cancer, remaining constant for over 20 years. Contralateral risk-reducing mastectomy should be considered in this group, in particular as there is a survival benefit. Caution is advised when counselling women considering risk-reducing oophorectomy as, after accounting for statistical bias, the associated risk reduction was found to be non-significant, and potentially smaller than has been previously reported. SNP testing did not add any further discriminatory information when assessing contralateral breast cancer risk
The impending demise of the item in visual search
No full textThe way the cognitive system scans the visual environment for relevant information - visual search in short - has been a longstanding central topic in vision science. From its inception as a research topic, and despite a number of promising alternative perspectives, the study of visual search has been governed by the assumption that search proceeds on the basis of individual items (whether processed in parallel or not). This has led to the additional assumptions that shallow search slopes (at most a few tens of milliseconds per item for target-present trials) are most informative about the underlying process, and that eye movements are an epiphenomenon that can be safely ignored. We argue that the evidence now overwhelmingly favours an approach which takes fixations, not individual items as its central unit. Within fixations, items are processed in parallel, and the functional field of view determines how many fixations are needed. In this type of theoretical framework, there is a direct connection between target discrimination difficulty, fixations and RT measures. It therefore promises a more fundamental understanding of visual search by offering a unified account of both eye movement and manual response behaviour across the entire range of observed search efficiency, and provides new directions for research. A high-level conceptual simulation with just one free and four fixed parameters shows the viability of this approach
Novel implementations of relaxation methods for measuring residual stresses at the micron scale
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