Naresuan University Journal
Not a member yet
39887 research outputs found
Sort by
Investigation of dynamic Saint-Venant’s principle in a cylindrical waveguide – experimental and numerical results
No full textA Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots.
No full textFacial pigmented spots are a common skin aging feature, but genetic predisposition has yet to be thoroughly investigated. We conducted a genome-wide association study for pigmented spots in 2,844 Dutch Europeans from the Rotterdam Study (mean age: 66.9±8.0 years; 47% male). Using semi-automated image analysis of high-resolution digital facial photographs, facial pigmented spots were quantified as the percentage of affected skin area (mean women: 2.0% ±0.9, men: 0.9% ±0.6). We identified genome-wide significant association with pigmented spots at three genetic loci: IRF4 (rs12203592, P=1.8 × 10(-27)), MC1R (compound heterozygosity score, P=2.3 × 10(-24)), and RALY/ASIP (rs6059655, P=1.9 × 10(-9)). In addition, after adjustment for the other three top-associated loci the BNC2 locus demonstrated significant association (rs62543565, P=2.3 × 10(-8)). The association signals observed at all four loci were successfully replicated (
ISTS: Implicit social trust and sentiment based approach to recommender systems
No full textWe propose a novel personalized Recommender System (RS) framework, so-called Implicit Social Trust and Sentiment (ISTS) based RS which draws user preferences by exploring the user’s Online Social Networks (OSNs). This approach overcomes the overlooked use of OSNs in Recommender Systems (RSs) and utilizes the widely available information from such networks. Bearing in mind that a user’s selection is greatly influenced by his/her trusted friends and their opinions, this paper presents a framework to apply a new source of data to personalise recommendations by mining their friends’ short text posts in microbloggings. ISTS maps suggested recommendations into numerical rating scales by applying three main components: (1) measuring the implicit trust between friends based on the intercommunication activities; (2) inferring the sentiment rating to reflect the knowledge behind friends’ short posts, so-called micro-reviews, using sentiment techniques adding several ONSs language features to empower the extracted sentiment; (3) identifying the impact degree of trust level between friends and sentiment rating from micro-reviews on recommendations by using machine learning regression algorithms including linear regression, random forest and support vector regression (SVR). Our framework takes into consideration the semantic relationships between rating categories when estimating ratings to users. Empirical results, using real social data from Twitter microblogger, verified the effectiveness and promises of ISTS
The influence of natural trace element distribution on the mobility of radionuclides. The exemple of nickel in a clay-rock
No full textComment on "Construction and destruction of a volcanic island developed inside an oceanic rift: Graciosa Island, Terceira Rift, Azores" by Sibrant et al. (2014) and proposal of a new model for Grasiosa's geological evolution
No full textEffect of drug efflux transporters on placental transport of antiretroviral agent abacavir.
No full textAbacavir is as a frequent part of combination antiretroviral therapy used in pregnant women. The aim of this study was to investigate, using in vitro, in situ and ex vivo experimental approaches, whether the transplacental pharmacokinetics of abacavir is affected by ATP-binding cassette (ABC) efflux transporters functionally expressed in the placenta: P-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2), multidrug resistance-associated protein 2 (ABCC2) and multidrug resistance-associated protein 5 (ABCC5). In vitro transport assays revealed that abacavir is a substrate of human ABCB1 and ABCG2 transporters but not of ABCC2 or ABCC5. In addition, in situ experiments using dually perfused rat term placenta confirmed interactions of abacavir with placental Abcb1/Abcg2. In contrast, uptake studies in human placental villous fragments did not reveal any interaction of abacavir with efflux transporters suggesting a large contribution of passive diffusion and/or influx mechanisms to net transplacental abacavir transfer
Search for dark matter in events with heavy quarks and missing transverse momentum in collisions with the ATLAS detector
No full textAnnihilation Anxiety and Crime
No full textThis article explores the psychoanalytic construct of annihilation anxiety in order to develop a more thoroughgoing engagement between criminological theory and contemporary psychoanalysis. Though a few criminologists have commented on crime, scapegoating and retribution using classic psychoanalytic ideas, we bring Hurvich’s current empirical work on annihilation anxiety to the discourse. Beginning with his definition of annihilation anxiety as ‘fears of being overwhelmed, merged, penetrated, fragmented, and destroyed’, we apply Hurvich’s measures to reactions to crime and insecurity and interpersonal, collective and international crime. We discuss doing criminology interpretively, applied to the dynamic connections between crime and reactions to it, including political and policy responses. We conclude that criminologists could and should help distinguish between potential and imminent threats, to advance a post-positivist approach to crime and other security threats. We argue that such an approach moves criminology toward a social science more humane and pragmatic for its conscious engagement with unconscious fears harboured amidst the purportedly rational calculi of justice
What a waste:Outsourcing and how it goes wrong
No full textThis is the first ever book to analyse outsourcing – contracting out public services to private business interests. It is an unacknowledged revolution in the British economy, and it has happened quietly, but it is creating powerful new corporate interests, transforming the organisation of government at all levels, and is simultaneously enriching a new business elite and creating numerous fiascos in the delivery of public services. What links the brutal treatment of asylum-seeking detainees, the disciplining of welfare benefit claimants, the profits effortlessly earned by the privatised rail companies, and the fiasco of the management of security at the 2012 Olympics? In a word: outsourcing. This book, by the renowned research team at the Centre for Research on Socio-Cultural Change in Manchester, is the first to combine ‘follow the money’ research with accessibility for the engaged citizen, and the first to balance critique with practical suggestions for policy reform