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    Energy Efficiency and Spectral Efficiency Trade-Off in MIMO Broadcast Channels

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    Spectral efficiency (SE) and energy efficiency (EE) are the main performance metrics for designing green radio (GR) networks; however they are conflicting criteria. Consequently, instead of separately focusing on either SE or EE, characterizing the fundamental trade-off between EE and SE of MIMO broadcast channels (BC) is significant for the development of green wireless communications. This paper investigates the fundamental EE-SE relationship in a multiple-input multiple-output (MIMO) broadcast channel, which is important for facilitating a desirable balance between energy savings and spectrum utilization. Through our investigation, we prove that EE-SE relationship for MIMO-BC is a quasiconcave function. Furthermore, EE is proved to be either strictly decreasing with SE or first strictly increasing and then strictly decreasing with SE. Based on these findings, we propose a two-layer resource allocation algorithm in order to tackle the comprehensive EE-SE trade-offs problem. The key of the proposed method lies in the inner-layer algorithm which is solved by applying the principle of multiple access channel - broadcast channel (MAC-BC) duality. The algorithm in its dual form is solved using sub-gradient method and bisection searching scheme. Simulation results confirm the theoretical findings and demonstrate that the proposed resource allocation algorithm can efficiently approach the optimal EE-SE trade-off for MIMO-BC

    Cardiorespiratory fitness levels and their association with cardiovascular profile in patients with rheumatoid arthritis: a cross-sectional study.

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    OBJECTIVE: The aim of this study was to investigate the association of different physical fitness levels [assessed by the maximal oxygen uptake (VO2max) test] with cardiovascular disease (CVD) risk factors in patients with RA. METHODS: A total of 150 RA patients were assessed for cardiorespiratory fitness with a VO2max test and, based on this, were split in three groups using the 33rd (18.1 ml/kg/min) and 66th (22.4 ml/kg/min) centiles. Classical and novel CVD risk factors [blood pressure, body fat, insulin resistance, cholesterol, triglycerides, high-density lipoprotein (HDL), physical activity, CRP, fibrinogen and white cell count], 10-year CVD risk, disease activity (DAS28) and severity (HAQ) were assessed in all cases. RESULTS: Mean VO2max for all RA patients was 20.9 (s.d. 5.7) ml/kg/min. The 10-year CVD risk (P = 0.003), systolic blood pressure (P = 0.039), HDL (P = 0.017), insulin resistance and body fat (both at P <0.001), CRP (P = 0.005), white blood cell count (P = 0.015) and fibrinogen (P <0.001) were significantly different between the VO2max tertiles favouring the group with the higher VO2max levels. In multivariate analyses of variance, VO2max was significantly associated with body fat (P <0.001), HDL (P = 0.007), insulin resistance (P <0.003) and 10-year CVD risk (P <0.001), even after adjustment for DAS28, HAQ and physical activity. CONCLUSION: VO2max levels are alarmingly low in RA patients. Higher levels of VO2max are associated with a better cardiovascular profile in this population. Future studies need to focus on developing effective behavioural interventions to improve cardiorespiratory fitness in RA

    Inverted sandwich arene complexes of uranium

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    The chemistry of arene complexes of uranium has for over half a century been an important facet of organoactinide chemistry. Within this extensive and burgeoning field, in the past two decades inverted sandwich complexes have emerged incorporating cyclobutadienyl, arene, cycloheptatrienyl, and cyclooctatetraenyl ligands. Herein, the field is reviewed with an emphasis on well-defined molecular species that have been unambiguously characterised by X-ray crystallography

    Impact of hepatic cirrhosis on outcome in adult cardiac surgery.

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    Increasing prevalence of hepatic disease is likely to translate in a growing number of patients with significant hepatic disease requiring cardiac surgery. Available cardiac risk stratification models do not address the risk associated with hepatic disease. However, weighted mean mortality rates based on previous studies of cardiac surgery in patients with hepatic disease demonstrate operative mortality rates that range from 9.88% (standard deviation [SD] 9.69) for patients in Child-Turcotte-Pugh (CTP) class A cirrhosis to 69.23% (SD 28.55) for patients with CTP class C cirrhosis. This review comprehensively appraises the pathophysiology of hepatic disease, reported clinical outcomes and considerations for risk stratification

    Religion and the Pathologization of Fandom: Religion, Reason and Controversy in My Little Pony fandom

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    Popular media and academic studies have often compared media fandom to a form of secularised religion, suggesting excessive and irrational involvement. Fans respond to this charge by emphasising rational elements of their fandom and the imagined worlds they explore. This paper examines fan response when the rationality of this imagined world is undermined through the fan object itself, focusing on Brony (adult "My Little Pony") fandom: a fandom often subject to media pathologization. Fans highlighted their role as cultural gate keepers, protecting children from irrationality, recast the text into an attack on poor scientific method, or used fandom as a forum to discuss religion. This paper argues that the “fandom as religion” metaphor patologizes both religion and fandom, and ignores the diversity of fan responses to religion

    Non-linear, cata-Condensed, Polycyclic Aromatic Hydrocarbon Materials: A Generic Approach and Physical Properties

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    A generic approach to the regiospecific synthesis of halogenated polycyclic aromatics is made possible by the one- or two-directional benzannulation reactions of readily available (ortho-allylaryl)trichloroacetates (the “BHQ” reaction). Palladium-catalysed cross-coupling reactions of the so-formed haloaromatics enable the synthesis of functionalised polycyclic aromatic hydrocarbons (PAHs) with surgical precision. Overall, this new methodology enables the facile mining of chemical space in search of new electronic functional materials

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