Naresuan University Journal
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Feasibility Study of Forming Bio-diesel Communities / ความเป็นไปได้ในการสร้างชุมชนไบโอดีเซล
No full textบทคัดย่อประเทศไทย เป็นประเทศที่มีการใช้พลังงานเพิ่มสูงขึ้นตลอดมา โดยในปี พ.ศ.2557 มีการใช้พลังงานสูงถึง 75,804 พันตันเทียบเท่าน้ำมันดิบ ทำให้ต้องสูญเสียเงินตราต่างประเทศในการนำเข้าพลังงานสูงถึง 1,306 พันล้านบาท ส่งผลให้เกิดปัญหามลภาวะต่อสิ่งแวดล้อม รวมถึงผลกระทบต่อสุขภาพอนามัยของประชากร หากมีการใช้น้ำมันไบโอดีเซล ผสมในน้ำมันดีเซล หรือทดแทนน้ำมันดีเซลจะช่วยลดความรุนแรงของปัญหาดังกล่าว บทความนี้มีวัตถุประสงค์หลัก เพื่อหาความเป็นไปได้ในการสร้างชุมชนไบโอดีเซล โดยพิจารณาจากพฤติกรรมการใช้น้ำมัน อุปทานของน้ำมันใช้แล้ว การจัดการกับน้ำมันใช้แล้ว และผลกระทบต่อสุขภาพ กรณีศึกษาอำเภอพิชัย จังหวัดอุตรดิตถ์ และอำเภอวัดโบสถ์ จังหวัดพิษณุโลก ผลการศึกษาด้วยสถิติเชิงพรรณนา พบว่า มีความเป็นไปได้ในการสร้างชุมชนไบโอดีเซล โดยในอำเภอพิชัย มีปริมาณน้ำมันใช้แล้วเพียงพอต่อการผลิตไบโอดีเซลเดือนละ 1,717 ลิตร ซึ่งน้อยกว่าอำเภอวัดโบสถ์ ที่มีน้ำมันใช้แล้วเพื่อผลิตไบโอดีเซลเดือนละ 3,554 ลิตร น้ำมันใช้แล้วเหล่านี้ หาได้จากร้านขายของทอด ประเภทอาหารทอด ได้แก่ ปลาทอด ไก่ทอด และหมูทอด และร้านค้าประเภทอาหารว่างทอด ได้แก่ ปาท่องโก๋ทอด ในอำเภอพิชัย และลูกชิ้นทอด ในอำเภอวัดโบสถ์ อย่างไรก็ดี ประชาชนในอำเภอทั้งสองมีความเสี่ยงที่จะบริโภคอาหารที่มีสารโพลาร์เกินกว่าระดับมาตรฐาน ซึ่งเป็นอันตรายต่อสุขภาพ ถึงร้อยละ 3.0-6.4 ของร้านค้าทั้งหมด คำสำคัญ: ความเป็นไปได้ น้ำมันใช้แล้ว ไบโอดีเซลชุมชน AbstractThe consumption of energy in Thailand has been increasing every time. In 2014, there were 75,804 thousand tons of energy consumed in comparison to raw oil. There were a lot of loss in foreign currencies for importing energy equivalent to 1,306 thousand million Baht which produced water pollution and bad health effect to people. If people could use more mixed diesel with bio-diesel or bio-diesel instead of pure diesel, it could reduce the severity of these problems. The main objective of this research paper was to study the feasibility of forming bio-diesel communities by considering the behavior of cooking oil consumption, the supply of used cooking oil, its management, and effects to health by choosing Phichai district in Uttaradit province, and Wat Both district in Phitsanulok province, as case studies. The descriptive statistics results revealed that there was feasibility of forming bie-diesel community and enough used cooking oil to produce bio-diesel in both districts. Phichit district had 1,717 litres of it per month, which was less than Wat Both district that has 3,554 litres of it per month. This used cooking oil could be found in fried food shops, namely fried fish, fried chicken, fried pork, and fried snack food, such as Pha Tong Koe in Phichit district and fried meatball in Wat Both district. However, people in both districts have high risk in consuming food that has Polar compound higher than standard level, which is dangerous for their health at 3.0-6.4% of all shops. Keywords: Feasibility, Used Cooking Oil, Community Bio-diese
The Plasma Membrane Calcium ATPase 4 Signalling in Cardiac Fibroblasts Mediates Cardiomyocyte Hypertrophy
No full textThe heart responds to pathological overload through myocyte hypertrophy. Here we show that this response is regulated by cardiac fibroblasts via a paracrine mechanism involving plasma membrane calcium ATPase 4 (PMCA4). Pmca4 deletion in mice, both systemically and specifically in fibroblasts, reduces the hypertrophic response to pressure overload; however, knocking out Pmca4 specifically in cardiomyocytes does not produce this effect. Mechanistically, cardiac fibroblasts lacking PMCA4 produce higher levels of secreted frizzled related protein 2 (sFRP2), which inhibits the hypertrophic response in neighbouring cardiomyocytes. Furthermore, we show that treatment with the PMCA4 inhibitor aurintricarboxylic acid (ATA) inhibits and reverses cardiac hypertrophy induced by pressure overload in mice. Our results reveal that PMCA4 regulates the development of cardiac hypertrophy and provide proof of principle for a therapeutic approach to treat this condition.</p
Search for anomalous couplings in the WtbWtb vertex from the measurement of double differential angular decay rates of single top quarks produced in the tt-channel with the ATLAS detector
No full textThe electroweak production and subsequent decay of single top quarks is determined by the properties of the Wtb vertex. This vertex can be described by the complex parameters of an effective Lagrangian. An analysis of angular distributions of the decay products of single top quarks produced in the t -channel constrains these parameters simultaneously. The analysis described in this paper uses 4.6 fb−1−1 of proton-proton collision data at s√=7s=7 TeV collected with the ATLAS detector at the LHC. Two parameters are measured simultaneously in this analysis. The fraction f11 of decays containing transversely polarised W bosons is measured to be 0.37 ± 0.07 (stat.⊕syst.). The phase δ−− between amplitudes for transversely and longitudinally polarised W bosons recoiling against left-handed b-quarks is measured to be −0.014π ± 0.036π (stat.⊕syst.). The correlation in the measurement of these parameters is 0.15. These values result in two-dimensional limits at the 95% confidence level on the ratio of the complex coupling parameters gRR and VLL, yielding Re[gRR /VLL] ∈ [−0.36, 0.10] and Im[gRR /VLL] ∈ [−0.17, 0.23] with a correlation of 0.11. The results are in good agreement with the predictions of the Standard Model
Measurement of the transverse momentum and ϕ∗ηϕη∗ distributions of Drell–Yan lepton pairs in proton–proton collisions at s√=8s=8 TeV with the ATLAS detector
No full textDistributions of transverse momentum pℓℓTpTℓℓ and the related angular variable ϕ∗ηϕη∗ of DrellΓÇôYan lepton pairs are measured in 20.3┬áfb −1−1 of protonΓÇôproton collisions at s√=8s=8 ┬áTeV with the ATLAS detector at the LHC. Measurements in electron-pair and muon-pair final states are corrected for detector effects and combined. Compared to previous measurements in protonΓÇôproton collisions at s√=7s=7 ┬áTeV, these new measurements benefit from a larger data sample and improved control of systematic uncertainties. Measurements are performed in bins of lepton-pair mass above, around and below the Z-boson mass peak. The data are compared to predictions from perturbative and resummed QCD calculations. For values of ϕ∗η<1ϕη∗<1 the predictions from the Monte Carlo generator ResBos are generally consistent with the data within the theoretical uncertainties. However, at larger values of ϕ∗ηϕη∗ this is not the case. Monte Carlo generators based on the parton-shower approach are unable to describe the data over the full range of pℓℓTpTℓℓ while the fixed-order prediction of Dynnlo falls below the data at high values of pℓℓTpTℓℓ . ResBos and the parton-shower Monte Carlo generators provide a much better description of the evolution of the ϕ∗ηϕη∗ and pℓℓTpTℓℓ distributions as a function of lepton-pair mass and rapidity than the basic shape of the data
Hemispheric specialisation within the superior anterior temporal cortex for social and non-social concepts
No full textStudies of semantic dementia, imaging, and repetitive TMS have suggested that the bilateral anterior temporal lobes (ATLs) underpin a modality-invariant representational hub within the semantic system. Questions remain, however, regarding functional specialization across a variety of knowledge domains within the ATL region. We investigated direct evidence for the functional relevance of the superior ATL in processing social concepts. Using converging evidence from noninvasive brain stimulation and neuropsychology, we demonstrate graded differentiation of right and left superior anterior temporal areas in social cognition. Whereas the left superior ATL is necessary for processing both social and nonsocial abstract concepts, social conceptual processing predominates in the right superior ATL. This graded hemispheric specialization is mirrored in the patient results. Our data shed new light on the classic debate about hemispheric differences in semantic and social cognition. These results are considered in the context of models of semantic representation and the emerging data on connectivity for left and right ATL regions
Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up
No full textFunctional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis.
No full textHundreds of genomic loci have been associated with a significant number of immune-mediated diseases, and a large proportion of these associated loci are shared among traits. Both the molecular mechanisms by which these loci confer disease susceptibility and the extent to which shared loci are implicated in a common pathogenesis are unknown. We therefore sought to dissect the functional components at loci shared between two autoimmune diseases: coeliac disease (CeD) and rheumatoid arthritis (RA). We used a cohort of 12 381 CeD cases and 7827 controls, and another cohort of 13 819 RA cases and 12 897 controls, all genotyped with the Immunochip platform. In the joint analysis, we replicated 19 previously identified loci shared by CeD and RA and discovered five new non-HLA loci shared by CeD and RA. Our fine-mapping results indicate that in nine of 24 shared loci the associated variants are distinct in the two diseases. Using cell-type-specific histone markers, we observed that loci which pointed to the same variants in both diseases were enriched for marks of promoters active in CD14+ and CD34+ immune cells (P <0.001), while loci pointing to distinct variants in one of the two diseases showed enrichment for marks of more specialized cell types, like CD4+ regulatory T cells in CeD (P <0.0001) compared with Th17 and CD15+ in RA (P = 0.0029)