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Gastric Schwannoma: A Postoperative Surprise - A Case Report
Gastric Schwannoma is a rare, slow-growing, and clinically non-specific submucosal tumor, originating from Schwann cells with an excellent prognosis after surgical resection. We report a clinical case of a patient presented with gastric schwannoma revealed by non-specific gastric signs and of which the definitive diagnosis is done through immunohistochemistry of the resected specimen, showing strong S100 protein positivity. The evolution is favorable after partial gastrectomy with a decline of two years. Through this case, we are trying to trace the rarity, strong similarities with gastric stromal tumors, and especially, the weak index of suspicion for this diagnosis
Cannabis Smoking and Risk of Lung Cancer - A Systematic Review and Meta-Analysis
Background: Cannabis is the illicit psychoactive substance the most consumed in the world. Little is known about the association between the use of cannabis and the risk of lung cancer.Objective: The objective of this meta-analysis is to determine whether the use of cannabis is a risk factor for lung cancer.Methods: We conducted a systematic review and meta-analyses of all language articles using relevant computerized databases. MEDLINE (online PubMed), Web of Knowledge, Embase, EBSCO CINAHL, ScienceDirect, Scopus, Cochrane Library, and Directory of Open Access Journals were searched to September 2014 for cohorts and case-control studies that assessed the risk of lung cancer associated with cannabis smoking. The literature search was performed with a combination of medical subject headings terms, "cannabis" and "lung neoplasms". Data extraction: Two investigators independently analyzed and extracted results from eligible studies. Our study's registration number on PROSPERO is CRD42014008872.Results: The search strategy identified 2476 citations. 13 studies were eligible for inclusion: 2 pooled analyses of 9 case-control studies, one case-control study, and 3 cohorts.The cumulative analysis for all the studies under a fixed-effects model showed that cannabis smoking determined an increased risk of developing lung cancer in the future (relative risk 1.22, 95% confidence interval 0.999–1.5; p=0.051), with no evidence of heterogeneity across the studies (I2: 34%; p¼0.01).Conclusions: The use of cannabis with or without tobacco smoking is associated with an increased risk for lung cancer
Non-Accidental Flecainide Overdose - A Case Report
Flecainide acetate is an antiarrhythmic drug used in the treatment of supraventricular arrhythmias. Flecainide causes very rare but often serious intoxications. These intoxications happen either due to a non-accidental overdose or because of a narrow therapeutic index in a patient who suffers from cardiomyopathy or has electrolyte abnormalities. We report an original case of a patient who had taken a high dose of flecainide with the aim of suicide. The patient suffered a cardiogenic shock with complications of lactic metabolic acidosis. Fast diagnosis is essential to reduce the high morbidity and mortality of this intoxication. The treatment plan is symptomatic. It aims at eliminating the poison and compensating cardiac function by treating the shock and the electrolyte imbalances. This allowed us to swiftly regain normal electrical and mechanical cardiac function in our patient. 3 weeks after the psychiatric consultation no sequelae were found. This case highlights that thorough history is essential to determine the diagnosis of a drug intoxication since the range of used products is wide. On the other hand, in case of any intoxication, while we apply a specific treatment, a well-managed, systematic, symptomatic treatment is essential to reduce morbidity and mortality
English as a Lingua Franca of Science in Morocco
EXTRACT: During the Golden Age of Arabic-Islamic science (8th to 13th centuries C.E.), and due to the Islamic extension in the world, where a large part of the earth, from southern Europe throughout North Africa to Central Asia and on to India, was controlled by and/or influenced by the new Arabic-Muslim Empire, the Arabic science translations from Greek, Latin, and Chinese into Arabic were necessary, which made Arabic as the only language of science in Africa, Asia, and Europe during that age. Between the 15th and 17th centuries, Latin took this strategic role, ..
Medical Simulation: Utilize, Inspire, Embrace , Verify
(Extract)I too have experienced the enthusiasm of an individual seeking to learn a new task. More years ago than I care to elaborate and before the proliferation of health care simulators, I visited the ER with a painful ache and had an interesting training experience with a youthful ER nurse. She looked around possibly to see if anyone could help or oversee her and noting that everyone else was busy and my veins were attractively prominent, she promptly asked if I would mind if she practiced drawing blood. Under duress due to pain perhaps, I agreed. I am not sure if the art and science of phlebotomy include the part of chasing the vein with the needle under the epidermis or whether it is at the 3rd or 4th stick that phlebotomy starts to become something akin to torture but thankfully after the 4th stick, I received an apology and a surrender from the novice nurse and we waited for a more experienced practitioner. That day I wished for a better way and hoped that no one else would need to endure the painful or even perilous results of such inexperience....
Silent Sinus Syndrome: A Retrospective Review of 11 Cases
Objective: The purpose of this study is to describe the clinical and radiological features of SSS, and to review therapeutic possibilities and their outcomes.Patients and Methods: Retrospective observational case series in the department of Arthur Vernes Institute between Mars 2007 and November 2012. Clinical records, including ophthalmology and otolaryngology evaluations as well as computed tomography scans and operative reports, were carefully examined. A literature review for relevant studies was performed to examine similar cases.Results: Eleven cases of SSS were identified. Nine men and two women (sex ratio 4.5), aged between 23 and 54 years (mean, 30 years). there was 3 to 4 mm enophthalmos in 10 cases (90.9%), and hypoglobus in all cases, with no effect on visual function. In all 11 cases, the maxillary roof (orbital floor) was drawn downwards, and one or more walls of the maxilla were concave. In 4 cases septal deviation was present. 8 patients (72.7%) underwent endoscopic sinus surgery, while 3 refused it. Septoplasty was performed in 4 cases (36.3%).Conclusion: The silent sinus syndrome is a rare entity. It mainly presents as unilateral enophthalmos in younger people and has very characteristic clinical and radiologic signs.This case series reports our diagnostic and therapeutic experience with this syndrome
Lymph Node Involvement in Upper Aerodigestive Tract Cancers - A Clinical Study at Specialities University Hospital of Rabat
Introduction: Cervical lymph node involvement has a major impact on prognosis and treatment decisions in patients with upper aerodigestive tract (UADT) cancer. Objective: The aim of this study was to assess the incidence and pattern of cervical lymph node (LN) metastases in cancers of the upper aerodigestive tract.Methods: This prospective study was conducted by the Department of ENT and Maxillofacial Surgery at Specialities University Hospital of Rabat, collecting data between October 2009 and December 2011. Lymph nodes were counted, clinically and radiologically localized, excised, then studied histologically.Results: During this period, 106 patients have been treated surgically with a recent diagnosis of UADT cancer. The average age of our patients was 55±13.3 years, while the male/female ratio was 3.5 to 1. More than half of our patients were operated on with cancer of the larynx (58.5%, n=62); 27.4% (n=29) of patients suffering from oral cavity cancer, and 14.2% (n=15) had cancer of the hypopharynx. Cervical lymph node invasion was estimated at 31.2% clinically, and 38.7% radiologically and histologically, distributed in different sites.Although the percentage of the invasion is almost similar clinically, radiologically, and histologically, the high number of false positives and true negatives according to clinical and radiological exams confirms that the specificity and sensitivity of these two exams are still poor compared to histology.Conclusion: Thus, cervical metastases have to be diagnosed histologically. Moreover, the low percentage of lymph node invasions in the case of a UADT cancer suggests that the use of the sentinel lymph node technique could be important, as it has been validated for small T1T2N0 tumors in the oral cavity. Further studies are needed to confirm its validity in the case of other UADT tumor types
Pedunculated Hepatic Hemangioma - A Case Report
Pedunculated hemangioma is a rare and atypical hepatic angioma. We report the case of a pedunculated hepatic hemangioma presenting as an abdominal sub-hepatic mass incidentally discovered in a 66-year-old woman with anal cancer. The diagnosis was strongly suggested by the vascular features of the lesion on spiral computed tomography (CT) and magnetic resonance (MR) imaging. Surgical removal of the mass was decided to prevent the potential risk of ischemic volvulus along the pedicle. Histopathological examination confirmed this diagnosis. Contrast-enhanced thin sections and subsequent multiplanar reconstructions on CT and MR are very helpful to show the angioma features and the pedicle linking the lesion with the liver
Malignant Orbital Tumors in Children: A Series of 4 Cases
Introduction: Malignant tumors in children are rare but serious conditions as they can impair function and survival. Tumors in pediatric patients can originate from the orbit. Rarely, the tumor spreads to the adjacent areas and occasionally it may metastasize.Objectives: The objective of this study is to present the common symptoms and the clinical and radiological characteristics of the most common malignant orbital tumors in children.Materials and methods: Through the discussion of 4 clinical cases of children presenting with exophthalmos due to a tumor, the authors highlight that clinical symptoms are usually less specific and that imaging has an important role in diagnosis, determining location, and local and regional expansion of the tumor in order to find the adequate therapy.Results: Our patients' ages ranged from 2 to 5 years. The revealing sign in each case was unilateral exophthalmos due to a tumor, which could only be reduced minimally or not at all. Its evolution has been rapidly progressive. Orbital imaging and histologic study, if a biopsy was possible, allowed guiding the positive diagnosis of the malignant nature and its local and regional spreading, as well as the adequate treatment.Conclusion: Orbital tumors are rare in the pediatric population. However, due to recent remarkable progress obtained through both complementary diagnostic tools and treatments, these malignancies deserve the attention of both ophthalmologists and pediatricians
Why an Open Access Journal
Extract: An Open Access (OA) journal can be defined as a journal that is digital, online, and free of charges for every internet user, also it does not really require any copyrights or licensing restrictions. All over the world, scientists are looking for journals that maximize and emphasize the chances of their work being cited because citations valorize their work and they somehow award the authors and give them intellectual recognition...