37495 research outputs found
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Phi Beta Kappa, Psi of California Chapter, Induction Ceremony 2025
https://digitalcommons.chapman.edu/pbk_induction_ceremony_2025/1028/thumbnail.jp
Phi Beta Kappa, Psi of California Chapter, Induction Ceremony 2025
https://digitalcommons.chapman.edu/pbk_induction_ceremony_2025/1035/thumbnail.jp
Phi Beta Kappa, Psi of California Chapter, Induction Ceremony 2025
https://digitalcommons.chapman.edu/pbk_induction_ceremony_2025/1039/thumbnail.jp
Phi Beta Kappa, Psi of California Chapter, Induction Ceremony 2025
https://digitalcommons.chapman.edu/pbk_induction_ceremony_2025/1047/thumbnail.jp
Phi Beta Kappa, Psi of California Chapter, Induction Ceremony 2025
https://digitalcommons.chapman.edu/pbk_induction_ceremony_2025/1048/thumbnail.jp
The Growing Rift between Holocaust Scholars over Israel/Palestine
A chasm has formed between Holocaust scholars concerning Israel/Palestine, deepening immeasurably since 7 October 2023. Unlike previous controversies in the field, the divide is not just historical or methodological; it revolves around academics’ role in the world today, particularly the public stand they choose to take on Palestine/Israel and Zionism. Two main camps have formed. Put reductively, one camp defends Israel, while the other defends Palestinians, although differences between individual scholars within each camp make for more of a spectrum than a clear-cut divide. How, despite a diversity of ideas and foci within each camp, did two academic-political antipodes solidify over several decades, and how have 7 October and the ensuing war widened the rift between them
Remodeling Pedagogical Evaluation Tools to Incorporate Student Self-efficacy and Sense of Belonging in Scientific Research
Curated undergraduate research experiences have been widely used at colleges and universities for decades to build student interest, technical preparation, and confidence in the pursuit of scientific careers. Educators often employ standardized survey instruments to evaluate learning outcomes for research experiences, but many of these assessments consider only technical skill development and career interests and are not rooted in discrete pedagogical theories. As higher education aims to create inclusive and equitable learning experiences for students, we argue that pedagogical assessment tools for undergraduate research experiences need to expand to consider outcomes such as increased science literacy, confidence in relational “soft” skills, and a sense of belonging to a community that values scientific inquiry. We report on and critique a survey instrument that uses validated metrics to evaluate student sense of belonging and the relational skills developed during an undergraduate research experience. We also provide a revised survey instrument that is founded in social and emotional learning principles and expectation disconfirmation theory. We describe best practices for remodeling the undergraduate research environment to prioritize these inclusive learning objectives alongside publishable research output that is sought by research advisors. Survey tools, like the one described here, are critical for helping colleges and universities train students in science while evolving to promote inclusivity, self-efficacy, and sense of belonging. Higher education programs will continue to produce scientists, but a focus on confidence-building and soft-skill development is essential for creating a general population that is scientifically literate and supportive and trusting of the scientific process
Global Estimates of the Storage and Transit Time of Water Through Vegetation
The time it takes for water to transit from the ground back to the atmosphere affects weather, climate, biogeochemistry and ecosystem function. The transit time of water through vegetation, defined as the age of water transpiring from vegetation since time of entry, is a particularly understudied aspect of the terrestrial hydrologic cycle. Here we use a synergy of satellite remote sensing measurements over a five-year period to estimate global aboveground vegetation water storage to be on average 484 km3, roughly half of which is stored in Earth’s water-limited savannah, grassland and shrubland ecosystems. We then combine these storage estimates with remotely sensed data for transpiration and find that mean transit times of water through aboveground vegetation vary from ~5 days in croplands to ~18 days in evergreen needleleaf forests, with a global median of 8.1 days. In herbaceous-dominated land-cover types with comparatively low water storage and high seasonal water use, such as grasslands, the water stored in biomass may be frequently transiting in less than one day. Our estimates contribute to resolving the role of vegetation in the terrestrial hydrologic cycle; plants store little water compared to other pools, and the time it takes to return that water to the atmosphere is among the fastest components of the hydrologic cycle
Black History Month: A Digital Library Exhibit
Our Black History Month digital display highlights the contributions of African American pioneers in medicine and provides helpful resources to support the health of African American communities. This display is part of the Leatherby Libraries\u27 Diversity, Equity and Inclusion initiatives in alignment with the Chapman University Strategic Plan for Diversity & Inclusion, fostering a diverse and inclusive campus climate
Safety of Omadacycline Versus Standard-of-Care Oral Antibiotic Treatment for Bone and Joint Infections: Interim Results from an Open-Label, Non- Inferiority, Randomized Controlled Trial
Background
The incidence of bone and joint infections (BJIs) continues to increase, and existing oral BJI antibiotics have limitations. Omadacycline may be a potential treatment option for BJI treatment due to activity against doxycycline-resistant S. aureus and ESBL-producing Enterobacterales for which there are often no viable oral options. However, the safety of omadacycline in this setting is poorly defined.
Methods
We performed an open label, randomized, controlled clinical trial of adults with BJIs in the outpatient setting. Participants were randomized to omadacycline-containing regimen (omadacycline 300mg po daily) or Standard-of-Care (SOC) antibiotics. Adjunctive antibiotics were permitted in addition to omadacycline. Safety labs were performed at regular intervals. Herein, we report an interim, descriptive analysis of safety data. Results Among the 59 participants enrolled to date, 31 (53%) were randomized to the omadacycline-containing regimen and 28 (47%) to SOC. Median age was 58 years old, 52 (88%) were male, 44 (75%) identified as Hispanic, 8 (14%) as African-American, and 4 (6%) as white. The most common BJIs were diabetic foot infections (52, 88%) and device infections (5, 8%). (Table) Combination therapy was used in 16 (52%) vs. 12 (43%) in the omadacycline-containing vs. SOC arms, and IV only therapy was used in 0 (%) vs. 5 (18%) in the two arms, respectively. Most commonly used SOC regimens included ciprofloxacin (8, 29%), doxycycline (7, 25%), amoxicillin/clavulanate (6, 21%), and levofloxacin (3, 11%). Commonly associated laboratory abnormalities included new or worsening renal insufficiency (2 (6%) in the omadacycline-containing arm vs. 5 (18%) in SOC) and transaminitis (2 (6%) vs. 4 (14%)). Adverse events were similar in the omadacycline-containing vs. SOC arms including nausea (6 (19%) vs. 4 (14%)), vomiting (0 (0%) vs. 4 (14%)), and diarrhea (5 (16%) vs. 2 (7%)). (Table) There was 1 drug-related serious adverse event in the omadacycline-containing arm due to likely hypersensitivity to omadacycline; the event resolved after drug discontinuation. Conclusion In this interim analysis of our ongoing trial, the safety of omadacycline for BJI appears to be similar to the SOC. More robust data on long-term safety is warranted