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Equitable Sustainability Literacy Guide: Creating a Resource Guide to Educate on Environmental Problems through a Social Justice Lens
Get PDFThe Equitable Sustainability Literacy Guide (ESLG) is an online resource guide created by three student interns (Jacqueline Jergensen, Haley Arnold, and Sage Block) and two librarians (Jennifer Embree and Neyda Gilman) at Binghamton University to educate the public on the environment, climate change, and sustainability through a social justice lens
Toxoplasma membrane inositol phospholipid binding protein TgREMIND is essential for secretory organelle function and host infection
Get PDFApicomplexan parasites possess specialized secretory organelles called rhoptries, micronemes, and dense granules that play a vital role in host infection. In this study, we demonstrate that TgREMIND, a protein found in Toxoplasma gondii, is necessary for the biogenesis of rhoptries and dense granules. TgREMIND contains a Fes-CIP4 homology-Bin/Amphiphysin/Rvs (F-BAR) domain, which binds to membrane phospholipids, as well as a novel uncharacterized domain that we have named REMIND (regulator of membrane-interacting domain). Both the F-BAR domain and the REMIND are crucial for TgREMIND functions. When TgREMIND is depleted, there is a significant decrease in the abundance of dense granules and abnormal transparency of rhoptries, leading to a reduction in protein secretion from these organelles. The absence of TgREMIND in-hibits host invasion and parasite dissemination, demonstrating that TgREMIND is essential for the proper function of critical secretory organelles required for successful infection by Toxoplasma
Digital scholarship and data science intersect in libraries: A needs assessment report
Get PDFThe following report summarized the results of a needs assessment completed in the fall of 2023 at Binghamton University by the Libraries’ Digital Scholarship team. The aim was to understand how data science-focused programming, as part of the digital scholarship’s offerings, would be utilized on campus. The report evaluates existing literature, summarizes findings from twenty-eight interviews done across campus, and lays out an action plan for the Digital Scholarship team’s future planning
Inflammatory Biomarkers Associated with Brain MRI Measures: Framingham Heart Study Offspring Cohort
Get PDFBrain MRI volumes measuring brain atrophy have been associated with risks for Alzheimer’s Disease (AD) and related dementia. Inflammatory biomarkers associated with brain MRI volumes may provide insight into the neuroinflammation associated with these diseases. The study aim is to identify circulating inflammatory biomarkers associated with total and regional brain MRI volumes in the Framingham Heart Study Offspring cohort. Participants (N=662, 52% female, mean age 62 years) free of dementia and stroke at the time of blood draw and who had MRI measures within five years were profiled using the OLINK Proteomics inflammation panel. Pairwise cross-sectional associations between 68 biomarkers and eight brain MRI volumes were investigated using linear mixed-effect models accommodating familial correlations and adjusting for covariates (age, age2, sex, time between blood draw and MRI measurement, age-sex interaction, and number of APOE ε2 and ε4 alleles), using FDR≤0.1 to declare significance. APOE genotype-stratified analyses were performed to explore effect modification. Higher levels of 8 proteins were significantly associated with smaller total brain volumes (TCBV), including CDCP1, HGF, IL6, IL8, MMP10, OPG, VEGFA, and 4E-BP1. Higher levels of SCF and TWEAK were significantly associated with larger TCBV, and higher levels of SCF were also associated with larger parietal gray matter volume. In APOE ε4 carriers, higher levels of IFNγ were associated with greater white matter hyperintensity volumes. Consistent with our findings, SCF has been shown to have neuroprotective effects in animal models. Further studies are needed to confirm these potential risk and protective factors and to elucidate mechanisms
The Bush Administration and Guantanamo Bay: The Difference Between Public and Private Information
Get PDFOne major factor of George Bush’s tenure was the War on Terror, and the aftermath, specifically the controversy surrounding the Guantanamo Bay prison. Bush and his cabinet consistently gave speeches, public addresses, and generally put out public information denying the use of enhanced interrogation techniques, or more commonly known as torture. In this delivery of misinformation, the American public is led to believe that their government is imprisoning terrorists and handling them according to their crimes, when in reality that could not be further from the truth. The Department of Justice then issued memorandums that would lead to Bush’s justification of giving the order to use enhanced interrogation. This “advice,” given in the form of memorandums, blatantly denies every public piece of information given by George Bush. The differences between “public” and “private” information are vast, and truly expose the conditions of Guantanamo Bay.https://orb.binghamton.edu/research_days_posters_2023/1076/thumbnail.jp
Healthcare: The Causative Factor of the Punitive Prison System
Get PDFThe laws and regulations put into place by the federal and state government regarding healthcare in New York State prisons do not compare to the ineffectiveness of them put into practice, and therefore have pushed a punitive system within correctional facilities. The lack of healthcare infringes on the rights of health guaranteed to every citizen, which includes the right to control their own bodies. By removing one of the only things inmates have control over in their lives causes their self-esteem, self-worth, and ambition to deteriorate. Without feeling healthy and strong physically, inmates feel incompetent and lack the motivation they need to grow and become the best version of themselves before they go back into the community. Neglecting the minimum standards of medical treatment given to inmates coerces punishment and specifically targets the inmate’s simply for being sick, therefore steering them away from rehabilitation, and towards recidivism.https://orb.binghamton.edu/research_days_posters_2023/1080/thumbnail.jp
The Fossils of Binghamton University
Get PDFDuring the Devonian Period (419 to 358 Mya), most of the North American continent including New York State would have been covered by a warm, shallow sea where marine life flourished. Binghamton\u27s paleontological/geological past is relatively unknown to those outside of the environmental science or geology sphere. This project seeks to display our fascinating past, encourage others to explore the field of geology and environmental science and provide insight on fossil hunting as a hobby. Within the boundaries of Binghamton University: The Nature Preserve, Fuller Hollow Creek, Stair Park, and Nuthatch Hollow contain fossils of marine organisms, tree debris and trace fossils such as burrows. Through using simple tools such as a hammer/geologist hammer, chisel, or just your bare hands - anyone can find themselves a cool piece of history and learn about Binghamton\u27s geological/paleontological past.https://orb.binghamton.edu/research_days_posters_2023/1094/thumbnail.jp
Intersection of Transgenderism and Disinformation
Get PDFTransgender Studies and Disinformation Studies are separate, emerging fields of scholarly inquiry. While disinformation about trans people is widespread and harmful, the two fields have not been extensively studied as intersecting realities, in part because they are so new. My research draws on theories and definitions of disinformation to analyze transphobic legal and political developments in the United States from 2020 to 2023. Specifically, I focus on trans panic laws to articulate the fundamental relationship between gender and accepted notions of common knowledge. Because large sections of the American population remain naive about non-binary genders, disinformation about trans people can be harnessed to create political power that can then be used to effect policy changes that have implications beyond the trans community. By articulating the intersection of transgender studies and disinformation, I contribute to broader discussions about gendered disinformation while also theorizing recent transphobic legal and political developments.https://orb.binghamton.edu/research_days_posters_2023/1100/thumbnail.jp
Binghamton University\u27s Effect on Housing Insecurity in Binghamton
Get PDFThe influx of Binghamton University students moving into the Binghamton area has led to a housing problem. Landlords make the price of housing expensive because the students can afford it, but the non-students that live in Binghamton cannot afford it and struggle to afford housing. This study collected data through interviews with a representative of NoMa, the Stakeholders of Broome County, and the Binghamton Students’ Tenant Union. I made a survey that students living off-campus can fill out about their experience living downtown. I also used data collected by ResLife about student housing. I used research from scholarly articles about the housing crisis in Binghamton and Binghamton University’s impact on the housing crisis. I found that Binghamton University student’s living downtown are directly contributing to the housing crisis in Binghamton and that the amount of student’s living downtown has to be limited by the city of Binghamton and Binghamton University.https://orb.binghamton.edu/research_days_posters_2023/1102/thumbnail.jp
Correlations Between Nicotine Usage, Mental Wellbeing, and Other Psychoactive Substances Among College Students
Get PDFNicotine use may be associated with risk of illicit drug use and lower mental wellbeing. However, this relationship among college students is unknown. The purpose of the study is to assess the relationship between nicotine use, illicit ADHD medication use, and the use of other specific psychoactive substances and mental health of college students. An anonymous survey was distributed online to several higher education institutions. About 700 participants self-reported on the use of ADHD medications, cannabis, nicotine, other psychoactive drugs, and mental distress. Data was analyzed using Pearson’s Correlation Coefficient in SPSS. Very frequent nicotine use was positively correlated with mental distress. Very frequent use was linked to Cannabis and LSD use in addition to unprescribed use of painkillers. Non frequent use was positively associated with use of psilocybin, ADHD medication, LSD, and sedatives. Nicotine users may be inclined to use psychoactive substances, which requires further research.https://orb.binghamton.edu/research_days_posters_2023/1139/thumbnail.jp