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Agent-Based Modeling to Stress Test New York State Healthcare Robustness
Full text linkThis study presents an agent-based model (ABM) to assess the resilience of New York State’s healthcare system during public health crises. The model simulates patient interactions, disease spread, and resource allocation, identifying critical vulnerabilities and evaluating strategies to avoid system collapse. Simulation results indicate that with just 10\% of the population infected, hospitals statewide can reach full capacity within ten days, causing significant care delays and an estimated 32,104 deaths within a 30-day period.
Sensitivity analysis revealed infection rates, base mortality, and travel-related delays as primary drivers of system outcomes. These findings highlight the critical need for expanded surge capacity, optimized patient routing, and timely interventions. The ABM serves as an essential tool for policymakers aiming to enhance healthcare preparedness and resilience against future crises
Tickets, Please!: Electronic Resources Troubleshooting Migration to LibAnswers
No full textIn the summer of 2024, several public service points within the Binghamton University Libraries made the switch to LibAnswers. One of the service points includes the Electronic Resources Troubleshooting Team (ERTT), who assist users with access issues with the Libraries’ electronic resources. This poster will discuss how the ERTT migrated from collecting troubleshooting ticket data manually through Google Sheets and answering via email to automatic population of data along with a response mechanism in LibAnswers
Sowing the seeds of community engagement (literally!): Outcomes of hosting a spring seed tabling series
No full textThe Seed Library at Binghamton’s Science Library offers a rotating selection of vegetable, flower, and herb seeds that are available for community members to take free of charge. Following a Halloween tabling event to distribute donated seed garlic, we created a three-part series of seasonally-appropriate tabling events for the Spring 2025 semester. Each tabling session featured seeds from the Seed Library, selected titles from the Sustainability Hub’s book collection, and a brief hands-on activity to teach a relevant gardening skill. This poster will share how we developed the series, marketing efforts, patron engagement, and lessons learned
An exploration of the impact of educational background on basic science and life sciences librarians
Full text linkThis study sought to investigate the influence of a science educational background on librarian interactions with basic and life sciences programs. Through semi-structured interviews with 14 librarians, the study identified several key themes: understanding and enjoying science is beneficial; previous experience influences librarians’ approaches; relationships are important; defining success is challenging; and collaborating with other campus units is unusual. Results suggest a science undergraduate or graduate degree and previous science-related work experience enhance librarians’ comfort and communication with scientists and highlight a lack of professional continuing education related to researcher workflows
Daydreamer
Full text linkDaydreamer is a collection of five poems that blend into a colorful collage. “A peaceful ancient town” depicts a typical day in Hoi An while “Summer noon melody,” written in traditional Vietnamese verse form lục bát (six-eight), describes a peaceful Vietnamese countryside village during harvest days. The tone immerses into the darkness of isolation in “Midnight piece” and then becomes calmer, allowing nature to shine in “The squirrel and the pond” which consists of haiku poems about the cycle of seasons and life, a classic theme in Japanese poetry. Finally, the collection concludes with “In the middle of the clear wide sky” which highlights a farewell moment during a vibrant show. While exploring new literary concepts, poetic techniques, and cultures, Daydreamer also focuses on visualizing vivid stories, guiding readers through a journey of emotions, and encouraging them to enjoy and be mindful of many little moments in life
From Questions to Insights: The Power of Scoping Reviews in Research
Full text linkThis webinar will provide an introduction to conducting a scoping review, an essential method for mapping key concepts, evidence, and gaps in research across various fields. Participants will learn the foundational steps involved based on the JBI and PRISMA guidelines. Demonstrations will include developing a protocol, a research question, and a search strategy as well as, selecting relevant studies, and synthesizing data. The session will cover best practices, challenges, and practical tips for effectively planning and executing a scoping review. By the end, attendees will be equipped with the tools and resources to initiate their own scoping review projects with confidence
Compromised Communication: The Threat of Disinformation to Rational Bargaining
Full text linkThis paper integrates theories of disinformation with the “Bargaining Model,” a theory in political science that explains why actors choose to go to war even though they might achieve their aims more efficiently through bargaining. As a case study, the paper takes a disinformation campaign during the Cold War and Russia’s war in Ukraine (2014-present) to provide evidence for the way that disinformation undermines international dialogue and bases the status quo in unreal conditions, thereby making the bargaining process irrational and diminishing the opportunity for resolution
Balanced at the Last Straw: Reflections on Sandwich Generation
No full textAbstract:
My dissertation, Life at the Last Straw, is a multimedia hybrid collection of poems and essays in two parts: written poetry collection and recorded poetry album. The album includes an accompanying reading list. This project is about coping with caretaking, neuro-divergence, deep, fierce love, and the frustrations of balancing my life as mother, advocate, daughter and wife against the challenges of creative work, completing my PHD, and becoming a writer.
I am a non-traditional student (over 50) in a nontraditional life, but the backdrop is in many ways typical: Raised in an extended multi-generational multilingual Italian immigrant family, trained in the stories, folk-wisdom, and inter-generational cooking traditions.
In my manuscript, I use cooking as sign posts and metaphors. What is the dynamic between these often conflicting realities? How did emotions, devotion, and culture play a part in the way I was raised and my view of cooking and the kitchen as my happy place? I wonder if it is possible to return there. I use creative writing and my spoken-word album not only to return, but to take readers and listeners there, too.
Who needs me more in sandwich generation: my parents, my husband, my children? What is care work and how does it pay intrinsically when it is in reality unpaid labor with endless responsibilities, especially as a “sandwich generation” caregiver? Is it ok for me to express a range of unbecoming emotions? Do I really have time to pursue the PhD? Is it too late for me?
My poems, essays, and voice album offer an exploration of these questions
Assessing the Effects of Antibody Glycosylation and Conjugation on Fc-mediated Effector Functions
Full text linkIncreasing research has been conducted on antibody drug conjugates (ADCs) for their oncology applications and potential as treatments for immunological diseases. ADCs usually covalently bind a cytotoxic drug (payload) via a linker to a monoclonal antibody, which targets specific antigens expressed on tumors, delivering the drug directly to cancer cells while minimizing off-target effects. In addition to binding antigens on tumor cells, antibodies also interact with immune cells to activate “effector functions”. This activation is largely driven by the binding of Fcγ-receptors (FcγR) to the Fc region of IgG, which connects the humoral immune responses and cell-mediated immune responses. Antibody characteristics, such as glycosylation and conjugation, affect how well they bind to FcγR.
In this paper, both heterogeneous endogenous cysteine ADCs and site-specific ADCs are investigated. Surface plasmon resonance (SPR) was performed to evaluate the binding of naked antibodies, deglycosylated (DG) naked antibodies, glycosylated ADCs, and deglycosylated (DG) ADCs to four different FcγR isotypes. This experiment was performed with HER2 ADCs. Additionally, the dissociation constant (KD) for HER2 samples was also determined to assess the binding affinity of the antibody and ADCs to each FcγR. When the small molecule N-(2-Hydroxyethyl)maleimide was conjugated to a HER2 antibody, the amount of binding to all four FcγRs decreased compared to that of the naked antibody. Furthermore, all the deglycosylated samples exhibited a lower amount of FcγR binding than their glycosylated counterparts.
Effector function assays were performed to evaluate antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). Consistent with the SPR experiment, deglycosylated HER2 and TROP2 samples exhibited reduced ADCC and ADCP activity compared to their glycosylated counterparts. Most deglycosylated samples showed little induction of ADCC or ADCP
Harpur Palate Volume 23, Issue 2
Full text linkContributors: Wendy BooydeGraff | Soramimi Hanarejima | L Mari Harris | Elizabeth Rosen | Karen Regen Tuero | Francis Walsh | Michele Zimmerman | Brittany Atkinson | Joselyn Busato| Sam Campbell | Rosa Crepax | Lindsay D\u27Andrea | Clare Flanagan | Ella Harrigan | Sierra Hixton | Sean Madden | Allie Stokes | Brian Benson | Rivka Clifton | Mea Cohen | Melinda Combs | Kiana Govani | Vivian Calderon Bogoslavsky | Shae Meyer | Hallie Fogarty | Ali Beheler | John Blair | Isra Cheem