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Declines in Tapentadol Use in the US but Pronounced Regional Variation
Abstract: Background: Tapentadol is an atypical opioid with a dual mechanism as a mu agonist and norepinephrine reuptake inhibitor. This study characterized tapentadol use in the United States (US) using three databases. Methods: Drug distribution data from 2010 to 2020 were extracted from the Drug Enforcement Administration (DEA)’s Automated Reports and Consolidated Orders System (ARCOS), including use per region (mg/person) and business activity (i.e., pharmacy). Tapentadol prescription claims from the Medicare and Medicaid programs for 2010–2020 were also examined. Results: The distributed amount of tapentadol was 3.5 tons in 2020. Distribution was over twice as high in southern (South Atlantic = 29.0 mg/person, East South Central = 28.8) relative to Pacific (12.9) or New England (12.8) states. Tapentadol use decreased nationally between 2012 and 2020 by −53.8%. Adult diabetes prevalence was significantly associated with tapentadol distribution in 2012 (r(50) = +0.44, p \u3c 0.01) and 2020 (r(50) = +0.28, p \u3c 0.05). Tapentadol prescribing to Medicaid patients declined −55.2% from the peak year, 2011, until 2020. Tapentadol prescribed by Nurse Practitioners accounted for over one-sixth (18.0%) of 2019 in Medicare. Conclusions: There has been a substantial decline over the past decade in tapentadol distribution and prescribing. However, the substantial regional differences may warrant further attention by opioid stewardship programs
Exploring the Interplay Between Economic Growth and Sustainable Development: A Complex Systems Approach to GSDP and SDGs in Indian States
Pursuing Sustainable Development Goals (SDGs) necessitates aligning business and management practices on a global scale. This paper delves into the intricate dynamics between Gross State Domestic Product (GSDP) and SDGs across diverse states in India, offering nuanced insights to policymakers, businesses, and stakeholders. This paper explores the dynamic relationship between Gross State Domestic Product (GSDP) and the Sustainable Development Goals (SDGs) in the context of India\u27s diverse states by applying modern machine learning techniques such as XG boost, Decision trees, and K mean clustering. The study delves into how economic growth influences the progress towards SDGs. The research integrates complex systems methodologies, combining exploratory data analysis, correlation analysis, and clustering to offer actionable insights for policymakers and businesses. The paper emphasizes the need for tailored strategies that consider the economic development stages of states to achieve sustainable development goals more effectively. Through this multidimensional approach, the study provides a comprehensive understanding of how GSDP can guide the pursuit of SDGs and proposes innovative, data-driven solutions for fostering sustainable growth across India
Lithium Mining and Resistance: Extractivism, Environmental Justice, and Indigenous Struggles
The Lithium Triangle, encompassing parts of Argentina, Bolivia, and Chile, holds more than half the world’s lithium reserves, making it a focal point for global green energy transitions. However, lithium extraction in this region has sparked significant environmental, social, and political tensions. This paper examines the socio-ecological impacts of lithium mining, including water depletion, ecosystem disruption, and the effects on Indigenous communities. Additionally, it explores local resistance movements against extractivism such as the Rio Blanco movement involving demands for community participation in decision-making. By analyzing case studies of Indigenous resistance and policy frameworks, this research highlights the tensions between economic development, environmental sustainability, and Indigenous sovereignty. The findings suggest that while lithium mining is crucial for renewable energy transitions, a just and sustainable approach must include local indigenous involvement and stronger regulatory frameworks to mitigate socio-ecological conflicts in the Lithium Triangle.https://orb.binghamton.edu/research_days_posters_2025/1001/thumbnail.jp
Class Actions and Environmental Justice: Are Lawsuits Driving Real Change?
How effective are class action lawsuits in implementing environmental change? In answering this question through meta-analysis, a focus will be placed on cancer clusters as a general theme. Every year there are several different cases by which plaintiffs attempt to obtain compensation for troubles caused by hazardous chemicals such as asbestos, polychlorinated biphenyls (PCBs), perfluoroalkyl and polyfluoroalkyl substances (PFAS), to name a few. The formation of the Environmental Protection Agency (EPA) in the early 1970’s, along with the enforcement of protective litigation, were used to put an end to the use of these dangerous chemicals. All of the data collected along with the history, impact, and result of each lawsuit will be analyzed to determine the overall effectiveness of class action lawsuits in implementing changes in environmental policies and practices. Through research, many different class action lawsuits will be compiled in hopes of revealing a commonality amongst them.https://orb.binghamton.edu/research_days_posters_2025/1005/thumbnail.jp
Not Just Your Average Superhero: The Affordances of Comics Journalism in Human Rights Reporting
Though graphic memoirs have become globally popular, many readers are unaware of comics journalism, the combination of news reports and comics illustrations. While this format lacks the claim to objectivity of photojournalism, it allows journalists to explore developing issues and histories with imagery and creativity that other media lack. Comics journalists such as Joe Sacco, Sam Wallman, and Dan Archer use their panels to shine light on important human rights and labor abuses, while also making sure readers have a vivid view of victims’ stories. In these authors’ works, memory emerges as a key site for illustration to help represent overlooked histories and traumas. Moreover, memories can elicit new forms of empathy between reader and interviewee by revealing the shadow of bottled abuses. Finally, this project explores how the disavowal of objectivity can become a resource for comics journalists, allowing them to acknowledge and reflect on their position and biases.https://orb.binghamton.edu/research_days_posters_2025/1018/thumbnail.jp
“Why Are We Boxing Me In?”: Nuances in Family Acceptance and Rejection for Queer Young Adults
Family acceptance and rejection of queer people has a significant impact on health outcomes, with queer individuals who experience rejection demonstrating higher rates of difficulties such as dysphoria and low self-esteem. However, dominant narratives of family acceptance and rejection often fail to recognize the many different social factors which influence how acceptance or rejection is understood within families, such as culture and religious affiliation. This qualitative study investigates how queer young adults conceptualize family acceptance and rejection as shaped by different contextual considerations. 21 participants aged 18-30 were interviewed using a semi-structured protocol. Researchers analyzed data through an extensive coding process to develop consensus for emerging themes. Analysis revealed experiences of acceptance rooted in consistency and normalization while rejection was characterized by shame and fragmentation. Expectations of acceptance and rejection were contextualized by culture and religion. Findings can help clinicians engage with queer people and their families to promote wellness.https://orb.binghamton.edu/research_days_posters_2025/1036/thumbnail.jp
Redlining and Incarceration: The Long Shadow of Housing Discrimination in Broome County
The incarceration rate in Broome County has surged by 680% since 1980. In the Binghamton area, low-income neighborhoods often have a higher, stricter police presence and less government support and development––a legacy of government redlining that has lingered even after the passage of the Fair Housing Act. This project helps connect the era of redlining with mass incarceration by first correlating Broome County incarceration rates with historically redlined zones. Then, using government census data, firsthand interviews with people incarcerated in the Broome County jail, local news archives, and a review of housing policies, it examines the rising issue of incarceration and links it to injustices from past decades in Broome County. These sources suggest how housing insecurity, financial disinvestment, and community neglect have contributed to mass incarceration and heavy policing in the county’s segregated, low-income, and Black neighborhoods.https://orb.binghamton.edu/research_days_posters_2025/1053/thumbnail.jp
How Multiplayer Video Games Influence Collaboration and Team Dynamics
Multiplayer video games create a unique environment where communication and collaboration impact gameplay. While strategizing with others is often essential to reach a goal, factors like game design, communication methods, and gaming culture all play roles in shaping team dynamics. This research explores multiplayer video games and their ability to influence collaboration and develop empathy amongst players. It analyzes how games function through gameplay footage, interviews, internal/external communication methods (like in-game text chats or Discord), and communities formed around these games. By examining team vs team games (such as Valorant), team vs goal games (Overcooked!), and player vs player games (Clash Royale and Fortnite), this project demonstrates how video games are not a monolith; rather, different types of games encourage or discourage teamwork and empathy. Genuinely toxic behavior is more common in competitive games where players face one another, while team vs goal games tend to be more conducive of cooperation and problem-solving. A lack of empathy between players on a team is also correlated with worse individual and team-based performance.https://orb.binghamton.edu/research_days_posters_2025/1086/thumbnail.jp