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Data related to the work entitled The Adsorption of Chlorpromazine on the Surface of Gold Nanoparticles and Its Effect on the Toxicity to Selected Mammalian Cells
No full textThis study aimed to synthesize chlorpromazine (CPZ) conjugates with gold nanoparticles (AuNPs) and assess their biological effects on human lymphocyte cell lines (HUT-78 and COLO 720L), as well as human (COLO 679) and murine (B16-F0) melanoma cells. The biological activity of the CPZ-AuNP conjugates was compared to that of free CPZ and well-characterized AuNPs. Cell treatments with CPZ, AuNPs, and CPZ-AuNP conjugates were analyzed using standard assays—MTT, LDH, and MDA—to monitor mitochondrial activity, membrane integrity, and lipid peroxidation, respectively. Results showed that positively charged CPZ-AuNP conjugates were more effective in reducing cell viability than AuNPs alone. A dose-dependent increase in membrane damage was linked to oxidative stress triggered by the conjugates. The biological effects were influenced by both the composition and particle size of the AuNPs. Overall, conjugation with AuNPs appeared to diminish CPZ's biological activity, and the cellular response varied depending on the cell line examined.</p
The role of dialdehyde kefiran as a crosslinking agent in chitosan/kefiran-based materials with “Henola” extracts: a biocompatible strategy in wound care
No full text1. General Information- **Data Set Title**: The role of dialdehyde kefiran as a crosslinking agent in chitosan/kefiran-based materials with “Henola” extracts: a biocompatible strategy in wound care- **Authors**: - Principal investigator and contact person: Dorota Chełminiak-Dudkiewicz, Nicolaus Copernicus University in Torun, e-mail: dorotachd@umk.pl.-Investigator: Miloslav Machacek, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Czech Republic, e-mail:machamil@faf.cuni.cz-Investigator: Jolanta Dlugaszewska, Poznan University of Medical Sciences, e-mail: jdlugasz@wp.pl-Investigator: Aleksander Smolarkiewicz-Wyczachowski, Nicolaus Copernicus University in Torun, e-mail: asmolarkiewicz@doktorant.umk.pl- **Date of data collection**: year 2025.- **Place of data collection**: Torun- **Keywords***: chitosan-kefiran films, dialdehyde kefiran, “Henola” hemp, plant extract, wound dressing materialsData language**: English- **Sources of funding**: National Science Center (NCN) competition: SONATA 18- UMO-2022/47/D/NZ7/01821.2. Overview of data and files- **File List**:Fig.1.tiff: Characterization of the native kefiran (Kef) and dialdehyde kefiran (DKef). The size distribution, SEM image, and 13C NMR spectra of the a) Kef and b) DKef; c) ATR-FTIR spectra of the Kef and DKef.Fig.2. tiff: Physicochemical properties of the obtained films. a) ATR-FTIR spectra, b) thermal analysis, c) SEM images, and d) AFM and profile images.Fig.3.tiff: Properties of the obtained films. a) swelling rate in different pH, b) biodegradation profile, c) antioxidant properties, d) antiinflammatory properties, and e), f) protein adsorption on the materials. *, #, $ indicate p < 0.05 when compared to the corresponding CS/Kef and CS/Kef/WE, respectively. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extract HSA- human serum albumin FB-fibrinogen DPPH - 2,2-diphenyl-1-picrylhydrazyl radicalFig.4.tiff: Biological properties of the obtained films. a) antimicrobial properties against S. aureus, P. aeruginosa, and C. albicans, b) cytotoxicity (n = 3, expressed as mean (SD)), and c) hemolysis assay (n = 3, expressed as mean (SD)). Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extract PC- positive control NC- negative controlgraphical abstract.tiff: graphical abstractRaw data: swelling.tab: A swelling test was performed at pH 5.6 and pH 7.4. The samples were weighed, and the degree of swelling was calculated using a formula. The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extracthas adsorption.txt: The fluorescence method determined the adsorption of human serum albumin (HSA) on the materials. Fluorescence spectra were recorded at various time intervals at 25 C, ranging from 290 to 400 nm and 300 to 500 nm for HSA and Fb, respectively, with an excitation wavelength of 280 nm, using a Jasco FP-8300 spectrofluorometer (Jasco, Tokyo, Japan). The spectral registration range was 285 - 400 nm, scanning speed 100 nm/min, and Em/Ex bandwidth 2.5 nm/5 nm. The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractAnti-inflammatory.txt: The raw data on the anti-inflammatory properties was determined by inhibiting the denaturation of bovine serum albumin (BSA) with the obtained materials. The results were recorded on a UV-1800 spectrophotometer. The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractAntioxidant.txt: The raw data on the anti-inflammatory properties was determined by the DPPH scavenging test. The results were recorded on a UV-1800 spectrophotometer. The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractfibrinogen adsorption.txt: The fluorescence method determined the adsorption of fibrinogen (FB) on the materials. Fluorescence spectra were recorded at various time intervals at 25 C, ranging from 290 to 400 nm and 300 to 500 nm for HSA and Fb, respectively, with an excitation wavelength of 280 nm, using a Jasco FP-8300 spectrofluorometer (Jasco, Tokyo, Japan). The spectral registration range was 285 - 400 nm, scanning speed 100 nm/min, and Em/Ex bandwidth 2.5 nm/5 nm. The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extracthemolysis test.tab: The ex vivo hemolytic activity of CS/Kef, CS/Kef/WE, and CS/Kef/EE films was tested on human red blood cells from an anonymous donor (Approval of the Ethical Committee of the Faculty of Pharmacy in Hradec Králové, Charles University no. UKFaF/46675/2023). A study was performed by Miloslav Machacek from the Faculty of Pharmacy in the Czech Republic. It was measured using a Tecan Infinite 200M plate reader. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extract PC-positive control NC-negative controlbiodegradation.txt: The biodegradability of materials was determined by monitoring their weight changes for 14 days. The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractmicrobiological C albicans.txt: Study of antimicrobial properties against C. albicans. A study was performed by Dr. Jolanta Długaszewska from the Faculty of Pharmacy at the Medical University of Poznań. The analysis was carried out by culturing bacterial strains in a BHI medium in the presence of the material. The data was prepared using GraphPad Prism 10. List of abbreviations: BHI - Bacterial Growth Medium CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractMRC 24h.tab: Study of cytotoxicity properties against MRC cells after 24 hours of incubation. A study was conducted by Dr. Miloslav Machacek from the Faculty of Pharmacy in the Czech Republic. Fluorescence (λex = 560 nm, λem = 590 nm) was measured using the Tecan Infinite 200M plate reader (Tecan Group Ltd., Männedorf, Switzerland). The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractMicrobiologia P. aureginosa.txt: Study of antimicrobial properties against P. aureginosa bacteria. A study was performed by Dr. Jolanta Długaszewska from the Faculty of Pharmacy at the Medical University of Poznań. The analysis was carried out by culturing bacterial strains in a BHI medium in the presence of the material. The data was prepared using GraphPad Prism 10. List of abbreviations: BHI - Bacterial Growth Medium CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractmicrobiologia S.aureus.txt: Study of antimicrobial properties against S. auerus bacteria. A study was performed by Dr. Jolanta Długaszewska from the Faculty of Pharmacy at the Medical University of Poznań. The analysis was carried out by culturing bacterial strains in a BHI medium in the presence of the material. The data was prepared using GraphPad Prism 10. List of abbreviations: BHI - Bacterial Growth Medium CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extractMRC 74h.tab: Study of cytotoxicity properties against MRC cells after 72 hours of incubation. A study was conducted by Dr. Miloslav Machacek from the Faculty of Pharmacy in the Czech Republic. Fluorescence (λex = 560 nm, λem = 590 nm) was measured using the Tecan Infinite 200M plate reader (Tecan Group Ltd., Männedorf, Switzerland). The data was prepared using GraphPad Prism 10. Legend: CS/Kef - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran CS/Kef/WE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola water extract CS/Kef/EE - film based on chitosan and kefiran, crosslinked with dialdehyde kefiran and enriched with Henola ethanol extract- **File formats**: tiff, tab, txt3. sharing and access information- **Licenses/Restrictions**: CC BY - Creative Commons Attribution 4.0. - **Related Publications**: https://pubs.rsc.org/en/content/articlelanding/2025/ma/d5ma00029g</p
Photochemical C3-amination of pyridines via Zincke imine intermediates
No full textSelective skeletal and peripheral editing of the pyridine moiety has broadly expanded the chemical space. While C-H functionalization at C2 and C4 positions are enabled by the inherent reactivity of this heteroarene, selective derivatization at the C3 position has long posed a significant challenge. Recently, based on a dearomatization-rearomatization sequence, involving Zincke imine intermediates, selective halogenation (-Br, -Cl, and -I) and isotopic labelling were accomplished. Here, we report a mild and regioselective method for C3-amination that relies on the photochemical reaction of Zincke imine with an amidyl radical generated from N-aminopyridinium salts. Mechanistic and theoretical studies indicate that radical intermediates are involved and explain the C3 regioselectivity of the reaction.</p
Research data for article: Performance Analysis of Data-Driven and Deterministic Latency Models in Dynamic Packet-Switched Xhaul Networks
No full textFiles include the data obtained during realization of project NCN OPUS 27 "Modeling and optimization of multi-service and multilayer Xhaul networks" ("Modelowanie i optymalizacja wielousługowych i wielowarstwowych sieci Xhaul").The data includes (a) the datasets used in machine learning (ML)-based analysis of maximum flow latencies in dynamic packet-switched Xhaul networks and (b) the results of simulation experiments performed in RING and MESH network topologies.The network scenarios, the datasets generation process, and the results analysis were presented in the article M. Klinkowski and D. Więcek, „Performance Analysis of Data-Driven and Deterministic Latency Models in Dynamic Packet-Switched Xhaul Networks”, Applied Sciences, vol. 15, no. 12487, 2025, pp. 1-23.</p
Polysaccharidase activity in the rumen of Jersey cow
No full text The aim of the present study was to investigate and compare the effects of different types of zeolites and their contribution in the diet on polysaccharidases activity in the rumen of heifers. Natural and synthetic zeolites and their various amounts (2 and 4% of the control diet) were used. The study was performed on 5 rumen-fistulated Jersey heifers in a 5 x 5 Latin square design with 5 dietary treatments (control, 2% natural zeolites – ZN2, 2% synthetic zeolites – ZS2, 4% natural zeolites – ZN4, 4% synthetic zeolites – ZS4) and 5 experimental periods. The samples of ruminal digesta were taken from animals before feeding and 3 h after feeding. The significant interactions of diet and sampling time were shown for cellulolytic (P = 0.005), xylanolytic (P = 0.050) and amylolytic (P = 0.044) activities. The addition of 4% ZN to the diet significantly increased pectinolytic activity in the rumen in comparison to control group (P = 0.035). Interestingly, an upward trend of amylolytic activity has been shown (P = 0.082) in ZN2 group. The incorporation of 2% ZS to the diet significantly increased cellulolytic activity compared to control (P = 0.020) and ZN2 diets (P = 0.002). It can be concluded that zeolites can act in the origin-and dose-dependent manner. An increased activity of carbohydrate-digesting enzymes can be related to buffering properties of zeolites, which create favourable conditions for the growth and development of microorganisms. Differences between zeolites action on studied parameters may be derived from their chemical composition and particle size.</p
Daily pollen concentration of 20 types of plants in Warsaw: pollination season 2024
No full textOverviewThe dataset contains in-situ measurements of daily plant pollen concentration for the pollination season of 2024. The data were collected with the Volumetric Pollen and Particle Sampler (Lanzoni VPPS 2010, Italy). The instrument is installed at the roof platform (20 m above ground) of the Warsaw Observatory Station of the Institute of Geophysics, Faculty of Physics, University of Warsaw (instrument coordinates: 52°12'39.6" N, 20°58'57.4" E, 132 m a.s.l).Taxonomic GroupsThe dataset includes daily pollen concentrations [number of grains/m3] of 20 taxonomic groups of plant pollen:CorylusAlnusTaxusPopulusUlmusSalixCarpinusBetulaAcerFraxinusQuercusPinaceaeFagusPoaceaeRumexPlantagoUrticaChenopodiaceaeArtemisiaAmbrosiaThere is an extra group that refers to unidentified grains that are however likely from the aforementioned 20 taxonomic groups; this group is referred to as:OthersFile informationThe data is stored in the file 2024_pollen_concentration_in_Warsaw.txt, which contains daily pollen concentrations for each identified type from 30.01.2024 to 22.10.2024. The daily pollen concentration [grains/m^3] is multiplied by RS-Lab's microscope's field of view factor (0.46), which is a standard procedure.A daily pollen concentration sample is measured over 24 hours, but the start time varies:From the start until May 9, 2024: from 14:00 to 14:00 the next day.May 10–28: from 13:00 to 13:00 the next day.May 29–June 11: from 12:00 to 12:00 the next day.From June 12 onward: from 11:00 to 11:00 the next day.File Structure1) Header:Line 1-3: metadata, each starting with a hashtag (#), describing the file content and measurement location.Line 4: blank line2) Dataset:The data includes daily concentrations of pollen grains per 1 m³.Line 5: names of taxonomic groups of pollenLines 6-272: daily concentrations per taxonomic groupColumn 1: date in the format [DD-MM-YYYY], starting from 30.01.2024.Columns 2-22: pollen types in the following order: CORYLUS, ALNUS, TAXUS, POPULUS, ULMUS, SALIX, ACER, FRAXINUS, FAGUS, CARPINUS, QUERCUS, BETULA, PINACEAE, URTICA, POACEAE, RUMEX, PLANTAGO, CHENOPODIACEAE, ARTEMISIA, AMBROSIA, OTHERSColumn 23: blank columnColumn 24: DAILY SUM that contains total daily pollen count [number of grains/m3]3) General Information:Decimal separator: dot (.)Column separator: tab (\t)Header denoted with: hashtag (#)Missing data represented as zero (0)Data Acquisition MethodologyThe Volumetric Pollen and Particle Sampler (Lanzoni VPPS 2010, Italy) operates at 10 liters per minute, collecting airborne particles over 24-hour hours. Every 7 days, the collected tape is segmented into daily samples, mounted on microscope slides, and stained for analysis. Pollen grains are counted and classified visually along four horizontal lines per segment. Pollen concentration in 1 m³ of air is determined using a conversion factor specific to each microscope applied to the count of each detected pollen type.ATTENTION:We offer a free access to this dataset. The user is however encouraged to share the information on the data use with the Remote Sensing Laboratory by sending an e-mail to rslab@fuw.edu.pl.In the case this dataset is used for a scientific communication (publication, conference contribution, thesis) we would like to kindly ask for considering to acknowledge data provision by adding the following statement in Acknowledgments: "We acknowledge the data originators Z. Rykowska, A.Tomczak, and I.S. Stachlewska for the quality-assurance, evaluation, and provision of data sets of the Remote Sensing Laboratory at the Faculty of Physics of the University of Warsaw, Poland."Zuzanna Rykowska and Iwona Stachlewska acknowledge that the pollen type identification was done within the European Commission Horizon 2020 program (RI-URBANS G.A. no. 101036245).Artur Tomczak and Iwona Stachlewska acknowledge that the review of the published dataset was done within the National Science Centre, Poland (NCN) funding (Preludium-BIS UMO-2020/39/O/ST10/03586).</p
PRELUDIUM 4/2021 AT - results of qualitative and quantitative analysis of amino acids in egg samples depending on the type of fodder, UHPLC
No full textThe database contains the results of the qualitative and quantitative analysis of amino acids. Amino acids were analyzed in eggs of laying hens in terms of the effect of different types of feed mixtures. The database includes automatically generated reports from LabSolution software and results in Excel files, obtained by means of Shimadzu UHPLC. The report contains a chromatogram, as well as concentrations and retention times of individual amino acids. In addition, the database contains the results of the total protein of the eggs tested.</p
Effect of struvite (Crystal Green) application on microbial activity and soybean yield – a preliminary study
No full textThe included data refer to the biometric characteristics of soybean plants fertilized with struvite. The biometric characteristics include basic soybean parameters such as stem mass, root mass, plant height, and the height of the first pod setting. The second data file concerns measurements taken at different wavelengths, which can be used to calculate the content of photosynthetic pigments. By measuring the intensity of light absorption at specific wavelengths, it is possible to calculate the chlorophyll content in plant tissues. This allows for the assessment of the plant's physiological condition, health status, photosynthetic capacity, and the effectiveness of fertilization.The study compared the chlorophyll content in soybean plants fertilized with struvite and superphosphate.</p
Adsorption Data for Activated WUT-1′(Ni) and WUT-2′(Ni) Materials
No full textThis dataset contains adsorption isotherms for activated porous materials WUT-1′(Ni) and WUT-2′(Ni), derived from the removal of guest solvent molecules from WUT-1(Ni) and WUT-2(Ni), respectively. Both compounds are based on the same decanuclear nickel(II) hydroxyquinolinato-carbonato cluster, with the molecular formula [Ni10(μ6-CO3)4(L)12], where L = 2-hydroxyquinolinate. Depending on crystallization conditions, the clusters self-assemble into two distinct porous network topologies: diamondoid (WUT-1) or pyrite-type (WUT-2). The materials exhibit reversible phase transitions and selective gas separation properties. The dataset includes raw experimental adsorption isotherms in the Adsorption Information File (AIF) format for various gases and temperatures. </p
Single-crystal 3D electron diffraction dataset for sodium oxalate
No full textElectron diffraction dataset collected from sodium oxalate (Sigma-Aldrich) micro crystals obtained by slow evaporation from water.Microscope: Thermo Fisher Scientific 200kV Glacios Transmission Electron Microscope (Cryomicroscopy and Electron Diffraction Core Facility at the Centre of New Technologies, University of Warsaw, Poland)Camera: Ceta-D camera (bin 2x2, rolling shutter, noise reduction mode)Collection Software: EPU-D (Thermo Fisher), SMV formatCollection Parameters: 200keV, -193C, 50um C2, gun lens 8, spot size 11, extraction voltage 3850V, parallel beam, beam diameter ~1.7 um, beam stop inserted, oscillation per frame 0.4 deg, 0.5 s exposure time, tilt speed 0.8 deg/s, rotation -60 to +60 degGrid: lacey carbon Cu 200 mesh glow discharged for 60s at 25mASample: sodium oxalate</p
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