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Using Nanoparticle Drug Delivery Mechanisms to Improve Eye Moisture Over Extended Periods of Contact Lens Wear
Get PDFMillions of people around the world suffer from dry eye symptoms as a result of extended contact lens wear. The objective of this design document is to engineer a solution for chronic dry eyes. The solution must be safe, effective, easy to use, and affordable. The goal of the treatment is to decrease tear film osmolarity by 20 mOsmol/L. Three types of nanotechnologies were considered for this task. The candidate solutions were 1) hydrogel contact lenses infused with lubricant-loaded liposomes, 2) lubricant-loaded microemulsions applied as eye drops, and 3) lubricant-loaded niosomes applied as eye drops. All solutions use polyethylene glycol 400 as the primary active ingredient in the lubricant. The three solutions provide a safe treatment option that allows increased bioavailability of drug and increased retention time, as well as controlled release of drug. A combination of candidates 1 and 3 – namely, hydrogel contact lenses infused with lubricant-loaded niosomes – seems to be the best solution because of excellent drug delivery kinetics and minimal safety concerns. The success of this project would encourage further research in niosome-based and contact lens-based drug delivery. It would also allow this company to expand research and development and further specialize in ocular drug delivery
On Erasure and Misrepresentation
Get PDFRepresentation is crucial concerning questions of justice and equity. The way a group is perceived by others dictates the way they will be positioned in society. This is a fact which has been modeled consistently throughout history. Those who are perceived as inherently criminal are more likely to be abused by the justice system, as in the case of Black people in the United States, while those who are viewed as inherently weak are less likely to access positions of power, as in the case of women around the world. This pattern illustrates the importance of perception and therefore representation. Mary Wollstonecraft’s A Vindication on the Rights of Woman, the Revisionaries documentary, Herodotus’ Histories, and the U.S. Constitution all illustrate the ability of a few people to dictate the positioning of various groups in society based entirely on the way individuals represent or misrepresent said groups. Although representation ostensibly implies increased visibility, when the available images are limited, those with platforms can use representation as a means of erasing or subjugating hitherto underrepresented groups.
Guys Like Gauguin: A Legacy of Colonialism
Get PDFPaul Gauguin’s body of work lives at the intersection of orientalist and primitivist myth. He had a conscious hand in creating the mythology surrounding his work; his imagination was the source for the fiction of both his own life events and depictions of non-Western cultures. Separating who Gauguin is as an artist from who Gauguin was as a man proves a difficult task. A large body of work exists dedicated to documenting and understanding Gauguin’s biography, investigating evidence that may or may not shed light on the truest or most honest version of Paul Gauguin
ISIS and the "War Makes States" Path
No full textThis paper discusses the progression and evolution of the Islamic State of Iraq and Syria, also known as ISIS. The author explains how the group has progressed since its conception, explores possibilities for its evolution in the future, as it relates to and affects the surrounding countries and the international arena. The author examines the question of whether Charles Tilly’s “War Makes States” theory can be applied to the group in past, present, and future. The author uses a combination of literature review, critical reading, and research to explain how ISIS follows Tilly’s thesis that states emerge over time from areas of violence and the actions of violent groups. The author concludes that, despite recent territorial losses, the Islamic State of Iraq and Syria is evolving towards statehood per Tilly’s model, and that this has ramifications for the rest of the world in that the international arena should act accordingly when dealing with the group in order to forestall this occurrence.
The Greatest Moral Question: The United States & Jewish Refugees During the Holocaust
No full textThe Greatest Moral Question: The United States & Jewish Refugees During the Holocaus
Strategic Visions Spring 2018: Volume 17, No. II
No full textStrategic Visions Spring 2018: Volume 17, No. I
Mind the Gap: The Relationship Between Socioeconomic Status and Educational Outcomes: A Literature Review
No full textIn The United States of America, higher education is seen as the beacon of social mobility. If one is born without access to wealth, power, or prestige, which are all increasingly interconnected, they are encouraged to change their circumstances by working hard in school and getting a degree, thus giving them higher earning power. This narrative is the one the middle and upper class public thinks is happening; the one lived by low-income people is drastically different. There are many contributing factors to differing outcomes in higher education for people from different socioeconomic backgrounds: biased standardized test questions, access to test prep programs, primary and secondary school quality, and even pre-natal conditions, to name a few. Students’ socioeconomic backgrounds correlate with educational attainment and outcomes of students; these influence students’ future earning power and socioeconomic status, which then directly and indirectly influences the outcomes of their children. Thus, the widening income gap is directly related to the post-secondary achievement gap and creates a self-perpetuating cycle of socioeconomic inequity. This paper addresses the inequality of the American education system, with a specific focus on higher education attainment
Allen, Jones and Hall: Black Social Entrepreneurship During the Early Republic
No full textIn the years after the Revolutionary War, the cities of Philadelphia, Pennsylvania and Boston, Massachusetts saw a dramatic increase in the social entrepreneurship of African- Americans. The prevalent disenfranchisement of African-Americans in the era of the early Republic, the signing of the Declaration of Independence while most Blacks were enslaved and denied their basic right to life, liberty, and their pursuit of happiness, created an American society filled with discrimination and injustice. In the midst of hypocrisy, Black men rose to the occasion and founded organizations that provided Blacks with a sense of identity, comfort, and support
Exhibiting an Unapologetic Fascist: Mario Sironi
No full textBenito Mussolini\u27s Fascist dictatorship over Italy in the period between world wars remains a troubling element of the nation\u27s history. It has heavily affected the contemporary politics and public displays of in addition to scholarship about the thriving artistic scene of that time, yet, the weight of Italy\u27s Fascist legacy has either comprised the primary focus of or been entirely absent from studies on art in the 1920s-1930s until a recent academic interest in reinvestigating the political and cultural atmosphere of the period. This paper underlines the importance of such renewed critical interests in chapters of painful history and how those interests can influence public perceptions of national history and its outreach into contemporary culture. Specifically, I will examine the written and exhibited discrepancies between the life of the painter Mario Sironi under the regime and the life of selected paintings that perpetuate his existence in contemporary Italy. By comparing La Famiglia del Pastore in "Roma Anni Trenta: La Galleria d\u27Arte Moderna e Le Quadriennali (1931 - 1935 - 1939)" at the Galleria d\u27Arte Moderna and La Solitudine in "Time is Out of Joint" at the Galleria Nazionale I will analyze how exhibitions of art shape the Italian public\u27s reception of this period. I contend that certain exhibiting styles can either deepen public reception and consideration for a work of art and the time from which it stems or can reduce understanding to that inspired by instantaneous connections, dependent on the institution\u27s or curator\u27s approach to context. For, no trip to a museum is simply a trip to a museum – whether actively or passively, museums shape how the public approaches the works in its halls and through these works, how the public approaches themselves and the world surrounding them
How Did Geography Affect the Haitian Revolution?
No full textThis paper concerns Haiti’s geography and how it affected the Haitian Revolution. Its aims involve detailing the geography (especially human and physical) of colonial Saint-Domingue at the end of the Eighteenth Century and investigating the impact of that geography on the Haitian Revolution. The study focuses chiefly on primary sources from France, Saint-Domingue, and the United States in the late Eighteenth and early Nineteenth centuries and uses them to narrate the relationship of the Haitian revolutionaries to the geography of their country. It paints a picture of colonial Saint-Domingue as a mountainous and sparsely-populated place, largely remote from the French metropole, and with certain regions alienated from each other by a lack of economic ties. It then discusses the unconventional, Fabian, and proto-Guerrilla tactics that the Haitian revolutionaries employed, including asymmetric warfare, the employment of the surrounding biome in manufacturing supplies and gaining positional advantages, and the use of mountainous jungle to bluff the enemy concerning the size and equipment of insurgent forces. It notes how this strategy works symbiotically with the local environment, and how it propelled the Haitian Revolution to victory and allowed the continuous maintenance of an upper hand against enemy armies despite a disadvantage in numbers and equipment and a pro forma colony-metropole relationship with France. It describes the ways in which this symbiotic relationship with geography not only won Haiti’s independence but also shook the world. This paper describes Saint-Domingue’s geography during the time of the Haitian Revolution, and then discusses the importance of this geography in the creation of the first revolutionary black republic