Ho Chi Minh City Open University Journal of Science
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Antioxidant, anti-inflammatory and anti-aging effects of urolithin A on UVB-induced HaCaT cells
No full textImpact of Different Plant Development Regulators on Yield Components and Growth in Peanut
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Infrared thermographic evaluation of root surface during warm vertical compaction technique
No full textThis study aimed to evaluate the effects of heat setting, plugger size, and dentin thickness on the temperature increase at the root surface during warm vertical compaction. A total of 96 mandibular premolars, 36 maxillary, and 36 mandibular central incisors were selected. All root canals were prepared using a 30/07 file. AH Plus sealer and gutta-percha were placed into the canals. In the mandibular premolars, small (40/0.025), medium (50/0.05), and large (60/0.06) pluggers were used, each set at temperatures of 180, 200, 220, and 250 degrees C. For the maxillary and mandibular incisors, a medium-sized plugger was used across all heat settings. Heat was applied to each sample for 3 s, and the maximum temperature was recorded during warm vertical compaction of gutta-percha using an infrared thermal camera. Multiple-linear regression models with dummy variables were utilized to estimate the predictive influence of heat settings, plugger sizes, and dentine thickness on root surface temperature. At 200 and 220 degrees C, the large plugger was associated with a significantly greater temperature increase compared to the small plugger. However, no significant interaction was observed between 250 degrees C setting and pluggers. Interaction between dentin thickness and heat setting indicated that thin dentin was associated with greater temperature increases at 220 and 250 degrees C
Macro-anatomical, histological, and ultrastructural investigation of glandulae anales in Anatolian ground squirrels
No full textIn this study, the anal glands of 10 adult Anatolian ground squirrels (Spermophilus xanthophrymnus) were examined through dissection, scanning electron microscopy (SEM), and light microscopy. The anal glands consist of three independent complexes positioned ventrolaterally to the anus. These glandular complexes were connected with the anal canal, the rectum, and with each other through muscular and connective tissue layers coursing in multiple directions. Each anal gland complex consisted of a glandular component and a sac-like structure. The sac structures of the anal gland complexes, which can evert, were visualized for the first time in this study using SEM. At the basal regions of the anal sacs, two distinct types of glandular clusters were identified. Type I apocrine glands, characterized by short excretory ducts, were located adjacent to the sac base, whereas Type II holocrine glands, with longer tubular ducts, were situated more distally. The study identified the presence of numerous interconnected sinusoidal vascular structures in both the glandular region of the anal complex and in the inner portions of the muscle bundles surrounding the anal complexes. These sinusoidal capillaries, previously unreported in the anal glands, likely represent erectile structures that engorge with blood and generate pressure to facilitate anal complex function
Artificial intelligence dependency among educators: a scale development and validation study
No full textThis study aims to develop a valid and reliable measurement tool to assess the level of dependency on artificial intelligence (AI) among educators (teachers and academics). An exploratory sequential mixed methods design was employed. In the first phase, qualitative data were collected from 32 teachers and academics using a semi-structured interview form. Additionally, the literature review was conducted on AI dependency. Based on the findings, a 55-item pool was created. Content analysis was used for the qualitative data, while Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were used to examine and validate the factor structure of the scale, respectively. The EFA results revealed a two-factor structure comprising 32 items: Dependency in Educational Processes and Dependency in Academic Processes, explaining 69.75% of the total variance. The Cronbach’s alpha reliability coefficient of the whole scale was found as 0.982. Additionally, to assess the scale’s reliability, a split-half method was used by dividing the items into two groups (odd and even). The Cronbach’s alpha coefficients for the first and second groups were 0.947 and 0.954, respectively, with a high and positive correlation between the two groups (r =.961). Furthermore, the Spearman-Brown coefficient was calculated as 0.980, and the Guttman split-half coefficient was also 0.980. Finally, CFA was applied on the 32-item version of the scale, and results confirmed the model with a chi-square/df ratio of 1.75 and an RMSEA value of 0.044. As a result, a valid and reliable tool was obtained to assess the dependency on AI among educators
Tarihi coğrafya yönüyle Burdur kazasında (1841 yılı) demografik yapı, göçler ve yerleşmeler
No full textRecycling-Based STEM Education for Sustainability: Effects on Secondary School Students’ STEAM Attitudes, Recycling Behaviours and Design Thinking Skills
No full textThis study examines the associations between participation in recycling-based STEM activities and secondary school students’ STEAM attitudes, recycling-related behaviours, and design thinking skills. A nested mixed-methods design was employed. The quantitative part used a one-group pre-test–post-test experimental design with 32 students, while the qualitative part included semi-structured interviews with 7 students selected through criterion sampling. Data were collected using a STEAM attitude scale, an attitude towards recycling scale, a design thinking scale and an interview form. Paired-samples t-tests were conducted for quantitative analyses, and the interview data were examined using content analysis. Statistically significant increases were observed from pre-test to post-test in students’ STEAM attitudes, recycling-related behaviours, and design thinking skills following participation in the recycling-based STEM activities. Qualitative findings indicated that students described coping with challenges in the design process by using problem-solving strategies and collaborating with peers. They also reported perceived increases in self-efficacy, creativity, and understanding of interdisciplinary (STEM) approaches. In addition, students reported greater awareness and described changes in recycling-related behaviours. Overall, the findings suggest that integrating recycling into STEM education may be associated with sustainability-oriented behaviours and higher-order thinking skills among secondary school students
Ảnh hưởng của tham nhũng đến hiệu quả hoạt động của các doanh nghiệp Việt Nam: Vai trò điều tiết của chuyển đổi số
No full textUsing panel data from 60 provinces in Vietnam over the period from 2010 to 2022, the research employs HDFE, 2SLS, and quantile regression methods to analyze the impact of corruption on firm performance in the context of digitalization. The findings support the sand in the wheel hypothesis, corruption undermines firm performance at the local level. Notably, digital transformation weakens the negative impact of corruption on firm performance. Furthermore, the study identifies time-cost efficiency as a key mechanism in the relationship between control of corruption and firm performance. These findings highlight policy implications for fostering business growth by strengthening the role of local digital transformation.Sử dụng dữ liệu bảng từ 60 tỉnh thành Việt Nam giai đoạn 2010 - 2022, nghiên cứu này sử dụng phương pháp hồi quy HDFE, 2SLS và hồi quy phân vị để đánh giá tác động của tham nhũng đến hiệu quả hoạt động của doanh nghiệp trong bối cảnh số hoá. Kết quả ủng hộ giả thuyết “bánh xe cát”, tham nhũng làm suy yếu hiệu quả hoạt động của doanh nghiệp ở địa phương. Đáng chú ý, chuyển đổi số làm giảm tác động tiêu cực của tham nhũng đến hiệu quả hoạt động của doanh nghiệp. Bên cạnh đó, nghiên cứu cũng chỉ ra rằng hiệu quả chi phí thời gian là một cơ chế quan trọng trong mối quan hệ giữa tham nhũng và hiệu quả doanh nghiệp. Kết quả này nhấn mạnh các hàm ý chính sách trong việc thúc đẩy tăng trưởng doanh nghiệp thông qua việc thúc đẩy vai trò của chuyển đổi số địa phương
"Surgical Management of Cyclosporine-Associated Gingival Hyperplasia in Patients with Idiopathic Thrombocytopenic Purpura: A Case Report
No full textSurgicalManagement of Cyclosporine-Associated Gingival Hyperplasia in Patients withIdiopathic Thrombocytopenic Purpura: A Case ReportAbstractBackground:Drug-induced gingival hyperplasia is a significant adverse effect of systemicmedications such as cyclosporine, phenytoin, and calcium channel blockers onperiodontal tissues. Cyclosporine, commonly used for its immunosuppressiveproperties, may induce gingival enlargement by increasing fibroblast activity.This study aimed to evaluate the periodontal and surgical management ofcyclosporine-induced gingival hyperplasia in the presence of concomitantIdiopathic Thrombocytopenic Purpura (ITP) and to emphasize the importance of amultidisciplinary approach in patients with a high risk of bleeding. CasePresentation: A 47-year-old female patient presented with complaints ofgingival swelling, bleeding, and pain. Her medical history revealed aplasticanemia and ITP. She had been taking cyclosporine (100 mg twice daily) andeltrombopag (50 mg three times daily) for approximately 1.5 years. Clinicalexamination demonstrated generalized fibrotic gingival hyperplasia affectingmastication, bleeding on probing, and localized suppuration. Oral hygieneinstructions and Phase I periodontal therapy were performed. Due to thelikelihood of cyclosporine-induced gingival enlargement, a consultation withthe relevant physician was conducted; however, modification of the medicationregimen was not considered appropriate. Prior to surgery, a hematologyconsultation was obtained to increase the platelet count to ≥100,000/mm³.Platelet replacement therapy was administered before both surgical sessions,and 2 g of oral amoxicillin was given as prophylaxis 30–60 minutes prior to theprocedures. Gingivectomy and gingivoplasty were performed in the maxillary andmandibular arches at two-week intervals, with platelet transfusion administeredone day before each surgery. Postoperatively, analgesics and antisepticmouthwash were prescribed as supportive therapy. Results:Although initial periodontal therapy resulted in a reduction of inflammation,surgical excision was required due to the extent of the gingival enlargement.The surgical procedures were completed under safe hematological conditions.Postoperative healing was uneventful, and functional as well as estheticgingival contours were successfully restored.Conclusion:This case demonstrates that cyclosporine-induced gingival hyperplasia can besafely and effectively managed with a multidisciplinary approach,even in the presence of ITP. Preoperative platelet optimization enhancedsurgical safety and resulted in satisfactory clinical outcomes. Regularperiodontal follow-up is essential to minimize the risk of recurrence. Keywords:Gingival Hyperplasia, Cyclosporine, Thrombocytopenia</p