Ho Chi Minh City Open University Journal of Science
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Associations between muscle microvascularization, strength, and physical performance parameters in sedentary women
No full textHematolojik Malignite ve Solid Organ Tümörü Tanılı Çocuk Hastalarda Candida Parapsilosis Kandidemisine Genel Bakış
No full textWhole genome sequencing of vancomycin resistant<i> Enterococcus</i><i> faecium</i> isolated from cat and dog
No full textVancomycin-resistant enterococci (VRE) have emerged a significant public health concern over past few decades due to their association with serious multidrug-resistant (MDR) infections. This study utilized whole genome sequencing (WGS) to perform molecular characterization of three VRE isolates previously recovered from two cats and one dog. The genomic DNA of the isolates was extracted and sequencing was performed using the Illumina Novaseq platform. The genomes of Enterococcus faecium HMKU_VREfm_Dog12, Enterococcus faecium HMKU_VREfm_Cat95 and Enterococcus faecium HMKU_VREfm_Cat103 consisted of 2707111 bp, 2715129 bp, and 2664256 bp, respectively with GC content of 37.95%, 38.03% and 38.01%, respectively. Multi-drug antimicrobial resistance genes conferring resistance to high level aminoglycosides (aac(6)'-aph(2)'), lincosamides (lnu(B) and lsa(E)), macrolides (erm(A), erm(B), msr(A), msr(C), and msr(B)), trimethoprim (dfrG) and tetracyclines (tet(L) and tet(M)) were identified. The sequence type (ST) of each isolate was determined using the Enterococcus PubMLST database. The isolates were found to belong to different STs (ST2248 in VREfm_Dog12, ST43 in VREfm_Cat95, and ST284 in VREfm_Cat103). The isolates carried only efaAfm (adhesion-associated protein) as virulence gene. To the best of the authors' knowledge, this study is the first to provide insights into genetic diversity of vancomycin resistant E. faecium (VREfm) strains isolated from dogs and cats using whole genome sequencing analysis in Turkey. The findings underscore the importance of genomic surveillance in monitoring the dissemination of MDR VREfm in pet animals
Liken Planus Tanısı Almış Bir Lezyonun Squamoz Hücreli Karsinomaya Dönüşmesi: Olgu Sunumu
No full textThe Diversity of Bacteria Isolated From The Urine Cultures of Outpatients and Antibiotic Resistance Profiles After a Major Earthquake
No full textAim: Urinary tract infections are widely seen throughout the world in any age group, and mostly in females. After a major earthquake in 2023, sanitation problems developed in the region due to several difficulties, environmental pollution as well as behavioural changes in hygiene as people were exposed to survive for a long time period without water and detergent, resulting in several infections. The aim of this study to determine the diversity of bacteria isolated from urinary tract infections of outpatients and the resistance of these bacterial strains against several antibiotics. Method: The study included 796 outpatients who applied at the urology policlinic of a secondary care hospital between April 2023 and May 2024. It was examined 159 positive urine culture. Findings: The most frequently isolated bacteria from urine cultures were Escherichia coli (n:87, 54.71%), coagulase negative staphylococci (CNS) (n:14, 8.80%), Klebsiella pneumoniae (n:12, 7.54%), Enterobacter spp. (n:10, 6.28%), and Enterococcus faecalis (n:9, 5.66%). Ampicillin and amoxicillin resistance of E. coli strains were 48.27% and 42.12% respectively. E. coli strains were mostly susceptible against amikacin (98.85%).Conclusion: Natural disasters such as earthquakes and floods may cause environmental pollution, thereby causing an increase in infections. Epidemiological and demographic changes occur in patient groups. Most of these infections can be prevented by taking precautions and environmental recovery. </p
