Ho Chi Minh City Open University Journal of Science
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    ẢNH HƯỞNG CỦA ÁP LỰC HỌC TẬP ĐẾN LO ÂU VÀ KIỆT SỨC HỌC TẬP Ở SINH VIÊN ĐẠI HỌC TẠI TP. HCM

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    In the context of higher education in Vietnam, where university students are increasingly exposed to academic competition and social as well as family expectations, mental health has become an issue of growing concern. This study aims to examine the relationships among academic stress, anxiety, and academic burnout among university students in Ho Chi Minh City. Data were collected from 320 students through a self-administered questionnaire using a five-point Likert scale. Established international measurement tools were employed, including the Academic Stress Scale (ASS), the Generalized Anxiety Disorder scale (GAD-7), and the Maslach Burnout Inventory-Student Survey (MBI-SS). Data analysis was conducted using Cronbach’s Alpha, Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA), and Structural Equation Modeling (SEM). The findings indicate that (1) academic stress has a significant positive effect on anxiety; (2) anxiety serves as a mediator in the relationship between academic stress and burnout; and (3) academic stress also exerts a direct effect on academic burnout. These results highlight the urgent need for mental health support programs in higher education and suggest strategies to reduce academic overload while enhancing students’ stress management skills.Trong bối cảnh giáo dục đại học tại Việt Nam ngày càng chịu nhiều áp lực cạnh tranh và kỳ vọng từ gia đình – xã hội, sức khỏe tâm thần của sinh viên đang trở thành vấn đề cần được quan tâm đúng mức. Nghiên cứu này nhằm xác định mối quan hệ giữa áp lực học tập, lo âu và tình trạng kiệt sức học tập ở sinh viên đại học tại TP. Hồ Chí Minh. Dữ liệu được thu thập từ 320 sinh viên bằng bảng hỏi Likert 5 mức, sử dụng các thang đo đã được kiểm định quốc tế: Academic Stress Scale (ASS), Generalized Anxiety Disorder (GAD-7) và Maslach Burnout Inventory–Student Survey (MBI-SS). Phân tích dữ liệu bằng Cronbach’s Alpha, EFA, CFA và mô hình SEM cho thấy: (1) áp lực học tập có tác động dương đáng kể đến lo âu; (2) lo âu đóng vai trò trung gian trong mối quan hệ giữa áp lực học tập và kiệt sức học tập; và (3) áp lực học tập ảnh hưởng trực tiếp đến kiệt sức học tập ở mức vừa phải. Kết quả nghiên cứu nhấn mạnh sự cần thiết của các chương trình hỗ trợ tâm lý học đường, đồng thời gợi ý các chiến lược giảm tải học tập và phát triển kỹ năng quản lý stress cho sinh viên. Abstract In the context of higher education in Vietnam, where university students are increasingly exposed to academic competition and social as well as family expectations, mental health has become an issue of growing concern. This study aims to examine the relationships among academic stress, anxiety, and academic burnout among university students in Ho Chi Minh City. Data were collected from 320 students through a self-administered questionnaire using a five-point Likert scale. Established international measurement tools were employed, including the Academic Stress Scale (ASS), the Generalized Anxiety Disorder scale (GAD-7), and the Maslach Burnout Inventory–Student Survey (MBI-SS). Data analysis was conducted using Cronbach’s Alpha, Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA), and Structural Equation Modeling (SEM). The findings indicate that (1) academic stress has a significant positive effect on anxiety; (2) anxiety serves as a mediator in the relationship between academic stress and burnout; and (3) academic stress also exerts a direct effect on academic burnout. These results highlight the urgent need for mental health support programs in higher education and suggest strategies to reduce academic overload while enhancing students’ stress management skills

    Các nhân tố kinh tế vĩ mô ảnh hưởng đến phát triển Chính phủ điện tử: Bằng chứng ngắn hạn và dài hạn tại Việt Nam

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    The purpose of this study is to investigate the relationship between the E-Government Development Index (EGDI) and key macroeconomic factors, namely labor productivity, exports, and inflation, in the context of Vietnam from 2000 to 2024. The EGDI data, originally published biennially by the United Nations, were interpolated to construct an annual time series, while independent variables were retrieved from the World Bank. Methodologically, the study employs the ARDL framework to capture both short-run dynamics and long-run equilibrium relationships, complemented by the Bounds test and post-estimation diagnostics to ensure robustness. The findings reveal that in the long run, labor productivity, exports, and inflation exert negative effects on EGDI, suggesting a weak alignment between economic growth and e-government reforms. In the short run, fluctuations in exports and productivity also show adverse impacts, while the error correction term indicates slow adjustment toward equilibrium. These results imply that enhancing EGDI requires more targeted policies: increasing public spending on information technology, developing national data platforms and digital customs systems to integrate trade liberalization with administrative modernization, and maintaining macroeconomic stability to safeguard fiscal capacity for digital investment.Bài nghiên cứu phân tích mối quan hệ giữa chỉ số phát triển chính phủ điện tử (EGDI) và các yếu tố kinh tế vĩ mô gồm năng suất lao động, xuất khẩu và lạm phát trong bối cảnh Việt Nam giai đoạn 2000 - 2024. Dữ liệu EGDI được nội suy từ bộ chỉ số biennial của Liên Hợp Quốc để tạo thành chuỗi thường niên, trong khi các biến độc lập được thu thập từ World Bank. Về phương pháp, nghiên cứu áp dụng mô hình ARDL phân tích tác động ngắn hạn và dài hạn, đồng thời tiến hành kiểm định Bound Test và các chẩn đoán hậu ước lượng nhằm bảo đảm tính tin cậy. Kết quả cho thấy trong dài hạn, cả năng suất lao động, xuất khẩu và lạm phát đều tác động tiêu cực đến EGDI, phản ánh sự thiếu gắn kết giữa tăng trưởng kinh tế và cải cách chính phủ điện tử. Trong ngắn hạn, biến động xuất khẩu và năng suất cũng ảnh hưởng bất lợi, trong khi tốc độ điều chỉnh về cân bằng diễn ra chậm. Những phát hiện này hàm ý rằng để nâng cao EGDI, Việt Nam cần tăng chi tiêu công cho công nghệ thông tin, phát triển nền tảng dữ liệu quốc gia và hải quan số nhằm gắn kết hội nhập thương mại với quản trị công, đồng thời duy trì ổn định vĩ mô để bảo đảm nguồn lực đầu tư bền vững

    Tác động của Chatbot đến sự hài lòng của khách hàng trẻ tuổi trong hệ thống đa kênh: Vai trò trung gian của vi phạm kỳ vọng và trải nghiệm cảm xúc

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    In the context of rapid advancements in Artificial Intelligence (AI), of applications in omnichannel sales are becoming increasingly common, primarily through chatbots. These tools are expected to enhance interactions and improve customer satisfaction. This study aims to assess the impact of chatbot functionality on customer satisfaction, mediated by two variables: expectation violation and emotional experience. The research adopts a quantitative approach using Structural Equation Modeling (SEM) with SmartPLS 4. Data were collected via an online survey using a convenience sample of 226 young consumers in Ho Chi Minh City. The results indicate that AI chatbot functionality helps reduce expectation violations and fosters positive emotional experiences, enhancing customer satisfaction. This study extends the theoretical framework of expectation violation and emotional assessment in omnichannel sales. It offers practical implications for managers seeking to leverage and refine AI to boost business performance. The findings clarify the role of AI in enhancing customer experience and reinforcing competitive advantage in the digital era.Trong bối cảnh công nghệ trí tuệ nhân tạo (AI) phát triển nhanh chóng, việc ứng dụng AI trong bán hàng đa kênh ngày càng phổ biến, đặc biệt là chatbot, công cụ được kỳ vọng tăng cường tương tác và nâng cao sự hài lòng khách hàng. Nghiên cứu này nhằm đánh giá tác động của chức năng chatbot đến sự hài lòng của khách hàng thông qua hai biến trung gian: vi phạm kỳ vọng và trải nghiệm cảm xúc. Nghiên cứu sử dụng phương pháp định lượng phân tích bằng mô hình cấu trúc SEM với phần mềm SmartPLS 4. Dữ liệu được thu thập thông qua khảo sát trực tuyến với mẫu thuận tiện gồm 226 người tiêu dùng trẻ tuổi tại Thành phố Hồ Chí Minh. Kết quả cho thấy chức năng chatbot góp phần giảm thiểu vi phạm kỳ vọng và thúc đẩy trải nghiệm cảm xúc tích cực, từ đó nâng cao sự hài lòng khách hàng. Nghiên cứu mở rộng khung lý thuyết về vi phạm kỳ vọng và đánh giá cảm xúc trong bán hàng đa kênh, đồng thời cung cấp hàm ý thực tiễn cho nhà quản trị trong việc vận dụng và cải tiến AI nhằm tăng hiệu quả kinh doanh. Phát hiện này làm rõ vai trò của AI trong việc nâng cao trải nghiệm khách hàng và củng cố lợi thế cạnh tranh trong kỷ nguyên số

    Effect of intermittent fasting on behavioral, biochemical and histopathological parameters in rats under Acrylamide exposure Efecto del ayuno intermitente sobre los parámetros conductuales, bioquímicos e histopatológicos en ratas expuestas a acrilamida

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    Acrylamide is a known neurotoxic and potentially carcinogenic compound. It remains as a major public health concern due to its widespread presence in heat-processed foods. Despite extensive research on acrylamide-induced toxicity, effective dietary strategies to mitigate its harmful impact remain limited. Intermittent fasting has recently emerged as a promising metabolic intervention shown to enhance cellular stress resistance and improve antioxidant capacity. This study was designed to investigate the effects of intermittent fasting on acrylamide-induced toxicity in rats. Wistar rats were randomly divided into four groups: control, acrylamide, intermittent fasting, and acrylamide + intermittent fasting. Intermittent fasting was applied every other day, while acrylamide was administered intraperitoneally at a dose of 30 mg/kg/day, three times per week. On day 28, behavioral assessments were performed using the Elevated Plus Maze, Open Field Test, hotplate, and rotarod tests. Biochemical analyses were conducted on blood samples, and oxidative stress parameters Catalase, Glutathione peroxidase, Superoxide dismutase were measured in liver, kidney, and brain tissues. Histopathological evaluations were also carried out. Histopathological findings indicated tissue damage in the acrylamide group and partial improvement in the acrylamide + intermittent fasting group. In the rotarod test, performance of the acrylamide + intermittent fasting group was similar to the control group, suggesting a protective effect. Catalase, Glutathione peroxidase, and Superoxide dismutase levels showed partial amelioration in kidney and brain tissues due to intermittent fasting. The results suggest that intermittent fasting may exert a protective effect against acrylamide-induced oxidative stress and behavioral impairments in rats. These findings highlight the potential of intermittent fasting as a non-pharmacological strategy to mitigate acrylamide toxicity

    Fıkıhta Faiz Konusu Mallar

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    "Surgical Management of Cyclosporine-Associated Gingival Hyperplasia in Patients with Idiopathic Thrombocytopenic Purpura: A Case Report

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    SurgicalManagement of Cyclosporine-Associated Gingival Hyperplasia in Patients withIdiopathic Thrombocytopenic Purpura: A Case ReportAbstractBackground:Drug-induced gingival hyperplasia is a significant adverse effect of systemicmedications such as cyclosporine, phenytoin, and calcium channel blockers onperiodontal tissues. Cyclosporine, commonly used for its immunosuppressiveproperties, may induce gingival enlargement by increasing fibroblast activity.This study aimed to evaluate the periodontal and surgical management ofcyclosporine-induced gingival hyperplasia in the presence of concomitantIdiopathic Thrombocytopenic Purpura (ITP) and to emphasize the importance of amultidisciplinary approach in patients with a high risk of bleeding. CasePresentation: A 47-year-old female patient presented with complaints ofgingival swelling, bleeding, and pain. Her medical history revealed aplasticanemia and ITP. She had been taking cyclosporine (100 mg twice daily) andeltrombopag (50 mg three times daily) for approximately 1.5 years. Clinicalexamination demonstrated generalized fibrotic gingival hyperplasia affectingmastication, bleeding on probing, and localized suppuration. Oral hygieneinstructions and Phase I periodontal therapy were performed. Due to thelikelihood of cyclosporine-induced gingival enlargement, a consultation withthe relevant physician was conducted; however, modification of the medicationregimen was not considered appropriate. Prior to surgery, a hematologyconsultation was obtained to increase the platelet count to ≥100,000/mm³.Platelet replacement therapy was administered before both surgical sessions,and 2 g of oral amoxicillin was given as prophylaxis 30–60 minutes prior to theprocedures. Gingivectomy and gingivoplasty were performed in the maxillary andmandibular arches at two-week intervals, with platelet transfusion administeredone day before each surgery. Postoperatively, analgesics and antisepticmouthwash were prescribed as supportive therapy. Results:Although initial periodontal therapy resulted in a reduction of inflammation,surgical excision was required due to the extent of the gingival enlargement.The surgical procedures were completed under safe hematological conditions.Postoperative healing was uneventful, and functional as well as estheticgingival contours were successfully restored.Conclusion:This case demonstrates that cyclosporine-induced gingival hyperplasia can besafely and effectively managed with a multidisciplinary approach,even in the presence of ITP. Preoperative platelet optimization enhancedsurgical safety and resulted in satisfactory clinical outcomes. Regularperiodontal follow-up is essential to minimize the risk of recurrence. &nbsp;Keywords:Gingival Hyperplasia, Cyclosporine, Thrombocytopenia</p

    ZİNCİRSİZ SALINCAK

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    Boosting Resistant Starch Type 3 in Amylotype Corn Starches via Combined Debranching and Extrusion Treatments

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    Resistant starch (RS), particularly type 3 (RS3), has garnered significant interest in food science due to its health benefits and functional versatility as a dietary fiber in processed foods. In this study, the combined effects of extrusion cycles and pullulanase debranching on RS3 formation in high-amylose corn starches were investigated. Starch–water (1:10) mixtures were autoclaved, treated with pullulanase, dried, and extruded at 50%, 60%, and 70% of feed moisture contents (100 rpm, 140°C). Solubility and water-binding capacity increased with extrusion compared to native starches, though emulsion properties were not similarly improved. All samples exhibited B+V-type crystallinity. While the type of crystallinity remained unchanged, relative crystallinity slightly increased with more extrusion cycles. Among the different extrusion feed moisture contents studied, 60% feed moisture resulted in extrudates with the highest RS3 content. RS3 content reached to 45.8% in Hylon V and 51.7% in Hylon VII after the starches were autoclaved, pullulanase-treated, and extruded at 60% moisture content for the third time (i.e., third extrusion cycle). However, there was no significant difference between the RS3 contents of the samples obtained after the second and the third extrusion cycles, indicating that more extrusion cycles do not always translate to higher RS3 concentrations. The high RS3 levels, combined with improved functional properties and thermal stability, suggest strong potential for incorporating these starches into food products as high-value dietary fiber ingredients

    Evaluation of the marginal and internal gaps of partially crystallized versus fully crystallized lithium disilicate CAD-CAM crowns

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    This in vitro study aimed to evaluate the internal and marginal adaptation of crowns produced from partially crystallized and fully crystallized lithium disilicate CAD-CAM blocks using direct view and the silicone replica method. The mandibular first molar was used as an abutment. A total of twenty crowns (n = 10) were produced using milling CAD-CAM. The direct viewing technique was used to measure the marginal gap. The measurement of internal adaptation was conducted using the silicone replica technique. Following the subsequent glazing procedure, all crowns underwent another round of measurements. The paired samples t-test was used to compare two related continuous variables. The study revealed that the mean value of the marginal gap of the partially crystallized block is significantly higher than the fully crystallized block both before and after the glazing process. A statistically significant difference was found before and after glazing of the partially crystallized block in the marginal gap values. The fully crystallized crowns showed better marginal gap values than the partially crystallized ones. No change was observed before and after the glaze in the fully crystallized block. The recommended limit of 120 mu m for the marginal gap of lithium disilicate CAD-CAM crowns was never exceeded

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    Ho Chi Minh City Open University Journal of Science
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