Ho Chi Minh City Open University Journal of Science
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Hatay Mustafa Kemal Üniversitesi Hastanesi Çocuk Kardiyoloji Polikliniği'ne başvuran adolesanlarda en sık başvuru nedenleri ve anksiyete düzeylerinin değerlendirilmesi
No full textKurtubî’nin el-Câmiʿ li-Ahkâmi’l-Kurʾân İsimli Tefsirinde Ahkâm Âyetlerinin Yorumunda Kıraat Farklılıklarının Rolü
No full textTextural, Pasting and Thermal Properties of Traditional Maras Tarhana Produced with Cracked Wheat
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Examining the Branching Patterns of the Hepatis Portae Vena with Computed Tomography Images
No full textBackground/Objectives: The present study aimed to examine the branching pattern images of the Hepatis Portae Vena (HPV), which is one of the vascular structures of the liver, with Computed Tomography (CT), and to uncover the surgical and radiological importance of the variations. Methods: The HPV branching patterns on CT images of healthy liver of 996 individuals (47.8% male, 52.2% female) between the ages of 20 and 59 were evaluated according to previously determined definitions. The division of the main branch of the HPV into ramus (r.), dexter, and r. sinister and the later division of r. dexter into r. anterior and r. posterior branches were called Type I-a, other main branch variations were called Type II-a, Type III-a, and Type IV-a, and the r. dexter variations were called Type V-b, Type VI-b, Type VII-b, and Type VIII-b. Also, all individuals in the present study were examined under four age groups as 20–29, 30–39, 40–49, 50–59, and the data were analyzed in the SPSS 21 software. Results: Type I-a (73.1%) was detected most frequently in all individuals, but Type VI-b (0.1%) and Type VII-b (0.1%) were detected least frequently. Following Type I-a, Type II-a (10.6%), Type III-a (8.2%), and Type V-b (5.5%) were detected, respectively. No statistically significant differences were detected between gender and age groups in terms of the frequency of HPV types (p > 0.05). Conclusions: We believe that accurate knowledge and definition of HPV anatomy will guide liver surgeries and interventional radiology, which are the cornerstones of the treatment of liver diseases
Enhanced neuroprotection against Alzheimer’s disease by combining <i>Inula viscosa</i> with curcumin: an <i>in vitro</i> study
No full textIntroduction:Alzheimer’s disease (AD), the most prevalent type of dementia among older individuals, is characterized by severe neurodegeneration with symptoms of progressive loss of cognitive capacity. We aimed to investigate the effects of curcumin (Curc) and Inula viscosa (IV) plant extracts on apoptosis and oxidative stress in an amyloid-β (Aβ)-induced in vitro AD model.Material and methods:The human glioblastoma cell line (U87) was treated with Aβ to produce an in vitro AD model. Treatment groups were: Aβ + Curc, Aβ + IV, and Aβ + IV + Curc. Cell viability assay was performed to analyze cytotoxicity. Caspase-3 (CASP3) levels were measured to evaluate apoptosis. For oxidative stress, glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD), total antioxidant (TAS), and total oxidant (TOS) levels were analyzed spectrophotometrically.Results:Combinatory application of IV and Curc post-Aβ treatment increased cell viability of U87 cells. Aβ-upregulated CASP3 levels were markedly reduced upon IV and Curc co-treatment. Anti-oxidant parameters, i.e., SOD, CAT, GPx, and TAS levels, were significantly elevated in the IV + Curc-treated group compared to the Aβ group. The elevated TOS level after Aβ exposure returned to its basal level upon Curc + IV co-treatment.Conclusions:IV + Curc co-treatment reduced apoptosis-related neurodegeneration and supported antioxidant activity in an Aβ-induced AD model of U87 cells. IV and Curc co-treatment can be a promising therapeutic strategy against AD.</p
