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    Data Management and Sharing Plan for: Reducing Structural Barriers to Health Equity in CF

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    The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project data

    Figure 2 Data

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    Includes all applicable data pertaining to Figure 2. Bead-bound stimulatory antibodies were used to activate PBMCs (n=3 canine donors) and frequency of activated T cells was determined by cell surface expression of CD25. Different antibody doses were utilized to determine optimal dose for superior T cell activation. The stimulatory effects of four different αCD3+αCD28 bead-bound antibody combinations (1:1 ratio) and two different αCD3+isotype bead-bound antibodies (1:1 ratio) were evaluated: CA17.6F9+5B8 beads, CA17.2A12+5B8 beads, CA17.6F9+1C6 beads, CA17.2A12+1C6 beads, CA17.6F9 beads, and CA17.2A12 beads. Data includes all applicable FCS and Prism files

    Data Management and Sharing Plan for: Evolutionary dynamics of zoonotic malaria

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    The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project data

    Replication Data for: Taking the first step: a pilot study of strategies to improve gait initiation in people with Parkinson disease

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    This study compared the effects of continuous walking training and gait initiation-specific training on gait initiation metrics in people with Parkinson disease

    Monmouth University Pennsylvania Poll, Number 262

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    This survey was conducted among Pennsylvania voters and address the election for US Senate and governor as well as issues facing the state

    Data Management and Sharing Plan for: Peripheral Neuropathy Research Registry

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    The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project data

    Impacts of warning labels on ultra-processed foods among Latino adults: A randomized trial

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    4,107 Latino adults (49% limited English proficiency) in the US participated in an online randomized trial using the Qualtrics survey platform. Participants viewed one of three labels: control labels displaying barcodes; identity warnings stating “WARNING: Ultra-processed food;” or health warnings stating “WARNING: Consuming ultra-processed food and drinks can cause weight gain, which increases the risk of obesity and type 2 diabetes”. Participants viewed four ultra-processed food (UPF) products (yogurt, fruit drink, breakfast cereal, and a salty snack) displaying their randomly assigned labels. Participants indicated whether the product was UPF (primary outcome) and rated perceived healthfulness of the product, intentions to purchase the product, and perceived message effectiveness (secondary outcomes)

    Couples' Daily Lives with Chronic Back Pain, 2021-2025

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    Purpose of the study: The majority of older Americans live with chronic health conditions and pain is the most common physical symptom experienced across conditions. For many older adults with chronic pain, the spouse is a key source of support and assistance; however, ongoing exposure to patients’ suffering is likely to take a toll on the health and well-being of these caregivers. Our recent research is based on prior work indicating that older spouses in a close marital relationship are more affected by their partner’s pain than spouses in a less close relationship. This intriguing finding supports the interpersonal model of elder caregiving and suggests a trade-off for older patients and spouses: is closeness good for the relationship but bad for spouses when patients are in more pain? We examined the daily and relational processes that underlie the impact of patients’ pain on spousal caregivers and their responses to patients, and how these processes influence longer-term outcomes for both partners. Participants: 152 married or long-term cohabiting couples age 50 and above in which one partner reported experiencing moderate or severe chronic back pain for at least 3 months. The ability to speak English was a requirement for participation. Couples had been together for an average of 38.2 years. Participants were recruited through several online resources from anywhere in the United States. All couples were mixed sex. Ethnicity was 85% White, 6% Black, 1.6% Asian or Pacific Islander; 7% unknown; 3.3% of the sample was Hispanic. The mean age of the sample was 71.8 years for patients and 70.9 years for partners. 59% of patients and 60% of their partners had at least a college degree. Median household income fell in the range of 50,00050,000-75,000. We did not ask about religion. Type of data: Both partners separately completed a daily diary at the beginning and end of each day for 30 days using a computer tablet provided by the researchers. Participants also completed a standardized relationship survey administered over the telephone at 5 time points, beginning at intake and then repeated every 6 months for 2 years. Procedural Overview: Couples were recruited and screened online primarily through BuildClinical, ResearchMatch and the University of Pittsburgh Gerontology Center. Recruitment occurred between April 2021 and August 2023. Relationship surveys were conducted by video by trained interviewers. Interviews were conducted at approximately 6-month intervals. Available data are: Time1: 152 couples; Time2: 147 couples plus 3 individuals; T3: 140 couples plus 6 individuals; T4: 138 couples plus 7 individuals; T5: 140 couples plus 5 individuals. All diary assessments were completed on an electronic tablet computer provided by the researchers. These data were collected via the REDCap system (Research Electronic Data Capture), beginning the day following the initial Time 1 interview and continuing for 30 consecutive days. ICBPs and partners were asked to complete two surveys per day, one between 30 and 60 minutes after rising (Beginning of Day; BOD), and another between 30 and 60 minutes before bedtime (End of Day; EOD). IRB: Couples' Daily Lives with Chronic Back Pain STUDY0001372

    Data Management and Sharing Plan for: Models of Post-Acute Care in Complex Older Adults with Fracture

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    The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project data

    Data Management and Sharing Plan for: Ovarian Hormone Withdrawal, Anhedonia, and Reward Function in Women with Premenstrual Exacerbations of Depression: A Crossover Randomized Controlled Trial

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    The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project data

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