Repositório de Dados de Pesquisa da Unicamp (Universidade Estadual de Campinas)
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1611 research outputs found
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Spectral characterization data of all quinazolinone compounds obtained from IR, ¹H NMR, ¹³C NMR, and HRMS
No full textSíntese e avaliação de 4-quinazolinonas como agentes anticâncer.
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Data related to evaluations of the photodynamic effect of S. aggregata extracts on SKMEL103, PC-3, PTN1A and HaCaT cell lines
No full textData related to the PhD research carried out by student Carlos Jose Alvarez Cantero, regarding the article entitled "Photobiological study of Sinningia aggregata extracts guided by cytotoxic and antibacterial evaluations using Photodynamic Therapy
Conjunto de dados associados à dissertação "Análise da maturidade dos relatórios de sustentabilidade publicados pelas empresas brasileiras: estudos exploratórios"
No full textO conjunto de dados se refere aos dados associados à dissertação denominada "Análise da maturidade dos relatórios de sustentabilidade publicados pelas empresas brasileiras: estudos exploratórios". Estão presentes os dados de entrada, coletados via questionário, para utilização dos métodos AHP, Grey Fixed Weight Clustering e Fuzzy TOPSIS Class
Alpha-terpineol esters: occurrence of the reaction by enzymatic route – Experimental analysis and molecular docking
No full textThis thesis chapter explores the enzymatic synthesis of ester derivatives of α-terpineol, a tertiary alcohol of high relevance in aroma chemistry. The study involved experimental screening with lipase variants and computational modeling to evaluate the reaction feasibility. Results revealed that under the tested conditions, enzymatic esterification of α-terpineol was unsuccessful, emphasizing the structural limitations imposed by its molecular conformation. Complementary chemical assays confirmed that esterification is viable via acid catalysis, reinforcing the hypothesis that steric hindrance prevents efficient biocatalysis in this case. These findings contribute to a better mechanistic understanding of enzyme-substrate interactions involving tertiary alcohols and inform future strategies for the biosynthesis of aroma-related esters
Método Bailarino-Pesquisador-Intérprete (BPI) e a dança do Brasil: interações e tensionamentos
No full textVídeo que acompanha a tese de doutorado em Artes da Cena - Instituto de Artes/ Unicamp
Optimized multiplex immunofluorescence for the characterization of tumor immune microenvironment in neoplastic paraffin-preserved tissues
No full textThe study of neoplastic cells enabled the discovery of important tumor-related biomarkers which resulted in new forms of early diagnosis, therapeutic options, and prognostic markers. Thus, immunofluorescence (IF), a high throughput imaging technology, represents a valuable method that enables the virtual characterization and localization of diverse cell types and targets, preserving tissue architecture and spatial surroundings. IF staining and analysis of formalin-fixed paraffin-embedded (FFPE) tissues are considered a challenge due to several difficulties, such as tissue autofluorescence, non-specific antibody binding, and image acquisition and quality. This study aimed to develop a multiplex-fluorescence staining technique with high-contrast and high-quality multiple-color images to enrich the investigation of important biomarkers. We present a robust optimized multiple-immunofluorescence procedure that reduced sample autofluorescence, enabled the use of simultaneous antibodies on the same sample, and showed super-resolution imaging through precise antigen localization. We illustrated the utility of this IF powerful method in FFPE neoplastic appendix, lymph node and bone marrow biopsies, and a 3D-coculture system, in which cells are enabled to grow and interact with their surroundings in all 3D dimensions. This optimized multiple-immunofluorescence method represents a powerful tool for better understanding the complexity of tumor cells, characterizing cell populations and spatial localization, revealing predictive and prognostic biomarkers, and identifying immunologic phenotypes in a single and limited sample. This IF represents a valuable method for tumor microenvironment profiling that could contribute to the study of cellular crosstalk and the niche, and to the identification of predictive biomarkers for neoplasms
Perfil de resistência, propriedades antimicrobianas, potencial probiótico e parâmetros cinéticos de crescimento de bactérias do ácido lático isoladas de leite de vaca
No full textO conjunto de dados trata-se de resultados obtidos de isolamento, caracterização e sequenciamento completo do genoma de bactérias do ácido lático isoladas de leite de vaca contendo curvas de crescimento, detecção de genes de resistência e parâmetros cinéticos de crescimento
Dataset on the enzymatic hydrolysis of rice bran protein concentrate using alcalase and flavourzyme
No full textBelow data refer to the enzymatic hydrolysis of rice bran protein concentrate (RBPC) using the commercial enzymes Alcalase and Flavourzyme. Hydrolysis assays were performed at three degrees of hydrolysis (3%, 6% and 12%), and all experiments were carried out in triplicate.
The dataset includes raw titration data obtained during pH-stat hydrolysis, using 1 M NaOH to maintain the reaction medium at the optimal pH for each enzyme. The recorded NaOH volumes correspond to the amount required to keep the reaction medium at the enzyme’s optimal pH and were used to calculate the degree of hydrolysis.
Two separate spreadsheets are provided, one for Alcalase and one for Flavourzyme. Each spreadsheet also includes information on the preparation conditions of the protein solution (solids content and heating parameters), the optimal temperature for enzyme activity, the enzyme inactivation temperature, and the corresponding hydrolysis kinetic data
Análise de variáveis bioquímicas e histopatológicas relativas à DHGNA
No full textLista de participantes anonimizad
Dados da recuperação e do processamento de pseudopalavras concretas, abstratas sociais e abstratas emocionais
No full textDados de um conjunto de experimentos psicolinguísticos sobre a recuperação e o processamento de pseudopalavras concretas, abstratas sociais e abstratas emocionais.
Testes de Leitura: Dados em CSV e XLSX dos tempos de leitura de cada segmento.
Testes de julgamento: Dados em CSV e XLSX dos índices e tempos de resposta.
Todos os dados poderão ser encontrados no OSF do depositante após publicação:
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