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Aanbevelingen van een computer:hoe betrouwbaar zijn ze?
No full textRecommender systems (letterlijk vertaald 'aanbevelingssystemen') zijn dedrijvende kracht achter aanbevelingen en feeds in onder andere webwinkels,streamingdiensten en sociale media. Deze aanbevelingen hebben grote invloedop welke artikelen we lezen of kopen, of welke meningen we horen. Echter, dezeaanbevelingen zijn vaak niet objectief, waardoor bestaande ongelijkheden in desamenleving kunnen vergroten. In dit artikel beschrijven we hoe transparantealgoritmes en verklaringen dit tegen kunnen gaan, en presenteren we interactiepatronendie gebruikers meer controle over hun aanbevelingen geven
Citizen science approaches in the development of post-stroke physical activity interventions:A scoping review
No full textBackgroundStroke is a major cause of disability globally, with high recurrence rates despite the implementation of secondary prevention strategies. Promoting physical activity and reducing sedentary behaviour are critical to mitigate these risks. Collaborative research approaches, including citizen science, offer promising methods for developing more effective and sustainable interventions by leveraging patient insights and lived experiences across different research stages.ObjectivesThis scoping review explored the application of citizen science approaches in developing interventions targeting physical activity and sedentary behaviour for people with stroke.MethodsFollowing Arksey and O’Malley’s framework and the PRISMA-ScR checklist, five databases were searched. We included empirical studies involving stroke patients in research on physical activity or sedentary behaviour interventions. Data was extracted on terminology, collaboration methods, and participant roles and analysed using the Participation Matrix framework. Methodological rigor was assessed using the CASP qualitative checklist.ResultsFourteen studies were included, most published after 2020 and originating from diverse countries. Terms like “co-design,” “co-creation,” and “patient and public involvement” were prevalent, but “citizen science” was not explicitly mentioned. Methods for active involvement of stroke patients included focus groups, workshops, and advisory panels. Stroke patients primarily participated as advisors or partners during intervention design, with minimal involvement in early research stages, data analysis, or dissemination. Researchers predominantly held decision-making roles.ConclusionsCitizen science in stroke research is still developing, with limited patient involvement across research phases. Expanding the depth and scope of patient involvement could enhance the relevance and long-term impact of interventions
The influence of ROS1 fusion partners and resistance mechanisms in ROS1-TKI-treated non-small cell lung cancer patients
No full textClinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 (n = 7). Clinical data were available for 50 patients (median age 62; 51% female; 32% never-smokers). Forty patients received tyrosine kinase inhibitors (TKIs), mostly crizotinib (n = 38). Crizotinib showed a 55% objective response rate (ORR) and a median progression-free survival (mPFS) of 5.3 months. Brain metastases (HR 2.65, 95% CI 1.06–6.60, P = 0.037) and prior chemotherapy (HR 3.17, 95% CI 1.35–7.45, P = 0.008) had a higher risk of progression. Sixteen patients received subsequent lorlatinib, with an ORR of 28% and mPFS of 3.7 months. G2032R and L2026M resistance mutations were identified in four lorlatinib non-responders, and in vitro studies confirmed resistance to lorlatinib. Fusion partners did not affect crizotinib outcomes. Lorlatinib was ineffective against on-target resistance. Real-world data showed lower TKI efficacy than clinical trials, highlighting the role of clinical and molecular factors in treatment response
Improving mental health literacy in secondary school educational professionals in the netherlands:adaptation of an existing intervention using Intervention Mapping Adapt
No full textBACKGROUND: Advanced interventions to enhance the mental health literacy (MHL) of educational professionals are now available, though their effectiveness varies, likely due to contextual differences. To adapt these interventions for use in other countries, a systematic and tailored approach is required to maintain the logical framework. This study describes the systematic process of selecting and adapting an intervention to improve MHL of Dutch secondary school educational professionals, using Intervention Mapping (IM) Adapt.METHODS: IM Adapt regards six steps: (1) assess needs and organizational capacity; (2) find evidence-based interventions; (3) plan adaptations; (4) make adaptations; (5) plan for implementation; and (6) plan for evaluation.RESULTS: The outcomes of a needs assessment were used to develop a logic model of the problem and of change, leading to the intervention goal of increasing mental health awareness, knowledge, attitudes, and self-efficacy among end-users. A logic model of the problem and of change visually outlines the relationship between a specific issue, its root causes, and the intended intervention to drive change. The existing evidence-based digital intervention, named LEARN, was identified as the most suitable for addressing these needs. This was done through reviewing the literature and existing intervention databases. Four main content adaptations were made to align with the distinct needs of the Dutch context and the evolving trends within the field of mental health, resulting in LEARN-NL, a digital mental health literacy intervention for Dutch educational professionals. Finally, implementers were identified, and a mixed methods feasibility study was set up.CONCLUSIONS: Our findings show that some content adaptations to LEARN were needed to address the needs and (learning) preferences of educational professionals in the Dutch education context, but that the majority of the existing intervention could be upheld. Existing evidence-based MHL interventions for educational professionals are useful as a basis for the adaptation and transfer to other countries. IM Adapt is a valuable framework for the systematic planning of adaptations to a new context while retaining its essential elements.</p
Feittypemodel van het begrip belanghebbende uit artikel 1:2 lid 1 Aeb in het omgevingsrecht
Get PDFDit beroepsproduct heeft geprobeerd op hoe gemeenten op een begrijpelijke manier inzicht kunnen krijgen in de complexiteit van wet- en regelgeving. Het beroepsproduct focust zich op het begrip belanghebbende in het licht van het omgevingsrecht. Hierbij wordt helderheid enstructuur gebracht aan artikel 1:2 lid 1 Algemene wet bestuursrecht (Awb). Om dit te kunnen bereiken is op basis van het onderzoek een feittypemodel gemaakt. Op basis van dit informatiemodel wordt het begrip belanghebbende uit artikel 1:2 lid in het licht van het omgevingsrecht helder gemaakt, waarbij de betekenis ervan op begrijpelijke wijze inzichtelijk wordt gemaakt.Voor de vertaling is de aanpak Wetsanalyse toegepast. Deze aanpak doorloopt zes stappen die de vertaling tot stand brengt. Hierbij is voor stap 1 het werkgebied bepaald. Daarbij zijn relevante bronnen geanalyseerd. In het onderzoek zijn wet- en regelgeving binnen en buiten de Awb wetsartikelen, jurisprudentie, kamerstukken en bijbehorende literatuur geraadpleegd.Deze houden allen verband met het begrip belanghebbende in het omgevingsrecht. Disclaimer:De afstudeeropdracht wordt uitgevoerd door een vierdejaarsstudent in het kader van zijn/haar afstuderen bij het Instituut voor Rechtenstudies. De student levert een juridisch beroepsproduct op en doet daartoe onderzoek. De student wordt tijdens de uitvoering van zijn/haar afstudeeropdracht begeleid door een afstudeercoach. De inspanningen van de student en de afstudeercoach zijn erop gericht om een zo goed mogelijk beroepsproduct op te leveren. Dit moet opgevat worden als een product van een (vierdejaars)student en niet van een juridische professional. Mocht ondanks de geleverde inspanningen de informatie of de inhoud van het beroepsproduct onvolledig en/of onjuist zijn, dan kunnen de Hanzehogeschool Groningen, het Instituut voor Rechtenstudies, individuele medewerkers en de student daarvoor geen aansprakelijkheid aanvaarden
Key Dimensions (and Factors related to) Student Success:Infographic
No full textTitleDefining Student Success as a Multidimensional Concept: a Scoping Review (additional files)DescriptionStudent success is a critically important concept in educational assessment and research. Yet, a universal definition of the concept has not been established. A comprehensive scoping review was conducted to define student success and take inventory of associated factors. This page contains files pertaining to the publication that presents the findings
De Groene Campus: videoverslag
No full textBeschrijving van de focus van het project 'Groene Campus'. Onderdeel van de Innovatiewerkplaats Campus Design onder het lectoraat facility management en het Kenniscentrum NoorderRuimte van de Hanze
Creatief Mislukken:er gaat wel eens iets mis
Get PDFEr gaat wel eens iets mis. Daar kun je flink van balen. Toch is het vaak wel de moeite waard om te proberen, te durven en te doen, zelfs als het kan mislukken. Iedereen heeft wel eens iets dat mislukt. Alles kan en hoeft niet altijd alleen maar goed te gaan. Kijk maar naar de verhalen in dit boek
De Prijs van kwetsbaarheid
No full textMartien Visser roept beleidsmakers op de prijs van onze kwetsbaarheid onder ogen te zien, te accepteren dat bij energie het optimum van de markt niet samenvalt met het optimum voor de maatschappij. “Verder moeten er ruim voldoende maatregelen worden genomen, waardoor Nederland en Europa een energiemarkt krijgen die tegen een stootje kan.
Comprehensive Needs Assessment for Enhancing Self-Management in People with Lipoedema and the Support Provided by Their Healthcare Professionals
No full textBackground: The cause of lipoedema remains unclear, and the condition is currently incurable. Effective self-management is therefore essential for coping with its physical and psychological impacts and the necessary lifestyle adjustments. This study aimed to assess the needs, barriers, and facilitators for enhancing self-management and self-management support from the perspectives of people with lipoedema and the healthcare professionals (HCPs) involved in their care. Methods: The study used a mixed-methods approach, incorporating a narrative review focused on people with chronic conditions and their HCPs, along with focus groups involving people diagnosed with lipoedema and the HCPs involved in their care. The Core Processes of the Intervention Mapping method guided a systematic approach to address the study’s objectives. Qualitative data were analyzed using a grounded theory approach. Results: Findings revealed unique self-management barriers for people with lipoedema, including limited awareness and expertise among HCPs, as well as stigmatization from both HCPs and society. Participants identified a need for tailored lifestyle plans, guidance, and support for monitoring progress. Key facilitators included self-management skills, supportive networks, and role models. HCPs noted barriers in communication and collaboration due to a lack of specialized professionals and negative attitudes toward lipoedema. They expressed a need for multidisciplinary/interprofessional teams, accurate diagnosis, patient openness, and reliable information resources. Facilitators included fostering trust, encouraging patient participation, and setting achievable goals. Conclusion: This study underscores the need for tailored self-management interventions for people with lipoedema. The adaptation of existing self-management strategies from other chronic conditions should take into account the specific needs, barriers, and facilitators of people with lipoedema and their HCPs