Hatay Mustafa Kemal Üniversitesi Akademik Veri Yönetim Sistemi
Not a member yet
37883 research outputs found
Sort by
Linking geopolitical risk, load capacity factor, income, labor, population, and trade on natural resources: Evidence from top oil-producing countries
No full textThe global economy has been witnessing increasing geopolitical risk (GPR) in recent years. The rise in GPR has several consequences, and the impact of this situation on natural resource rent (NR) has not yet been analyzed for the major oil-producing countries. Given this deficiency, this study analyzes the impact of GPR, gross domestic product, the labor force (LBR), load capacity factor, population density, and trade openness on the NR for the five major oil-producing countries (namely, Canada, China, Russia, Saudi Arabia, and the United States of America). To this end, the study analyzes data for the period 1995/Q1-2021/Q4 by using a cross-sectional Autoregressive Distributed Lag approach. The results demonstrate that (i) an increase in GPR and load capacity factor declines the NR; (ii) an increase in gross domestic product stimulates the NR; and (iii) a rise in population density, labor force, and trade openness has a stimulating impact on the NR. Overall, the research shows that all variables substantially impact the NR. Based on the results, various policy options are discussed, such as assessing geopolitical tensions as leverage to sustainably regulate the natural resource market and growth to prevent negative impact from managing the NR effectively for the five major oil-producing countries
Pharmacokinetics and bioavailability of cefuroxime in Nile tilapia (Oreochromis niloticus)
No full textCefuroxime is a broad-spectrum antibiotic extensively utilized in humans and animals. Although it has been reported as beneficial against certain fish infections, pharmacokinetic studies are lacking. The purpose of this study was to evaluate the pharmacokinetics of cefuroxime following intravascular (IV, n = 72), intraperitoneal (IP, n = 72), intramuscular (IM, n = 72), and oral (n = 72) administration of 20 mg/kg in Nile tilapia (Oreochromis niloticus) maintained at 29 ± 1.5 °C. Two hundred and eighty-eight fish were equally distributed among four treatment groups: IV, IP, IM, and oral. Blood samples were obtained from 6 fish per group at 12 distinct time intervals over a duration of 96 h. Cefuroxime plasma concentrations were quantified with high-performance liquid chromatography and subsequently evaluated through non-compartmental analysis. Following IV injection, the t1/2ʎz was 8.04 h, the Vdss was 1.03 L/kg, and the ClT was 0.14 L/h/kg. The Cmax of cefuroxime was 53.38±4.28 µg/mL at 0.25 h for IP injection, 28.70±3.41 µg/mL at 0.5 h for IM injection, and 6.77±0.81 µg/mL at 1 h for oral administration. Bioavailability was 80.26% (IP), 69.05% (IM), and 24.35% (oral). This study found that a dosing interval of 24 h for IP and IM injection or 8 h for oral administration is efficient for treating bacteria with a MIC value of ≤ 1 µg/mL. The findings of this study indicate that IP and IM injections of cefuroxime are applicable in tilapia. However, since oral administration is important in aquaculture, studies are needed to develop new formulations with better absorption, to demonstrate therapeutic efficacy in infected fish, and to determine the tissues residue depletion
Radiographic reliability of anatomical knee landmarks for joint line determination in healthy adults
No full textBackground: The correct identification of the knee joint line is essential for successful primary and revision total knee arthroplasty (TKA). Small misalignments can cause restricted range of motion, patellofemoral maltracking, and extensor mechanism imbalance leading to pain and functional impairment. This study aimed to evaluate the reliability of five radiographic anatomical landmarks — the fibular head, inferior patellar pole, tibial tubercle, and both femoral epicondyles — for estimating the joint line level in healthy Turkish adults. Methods: A retrospective radiographic analysis was conducted on 100 healthy adults (61 male, 39 female; 18–50 years). Perpendicular distances from these five bony landmarks to the joint line were measured digitally by two independent observers using a PACS system under standardized calibration to minimize projection errors. Inter-observer reliability was assessed by the intraclass correlation coefficient (ICC). Power analysis was based on the fibular-head–joint-line (FH–JL) distance as the primary outcome measure. Results: The FH–JL distance measured 11.4 ± 1.8 mm with a coefficient of variation of 15.8%, showing the highest reliability. Sex-based differences were significant (11.8 mm in men vs. 10.7 mm in women, p = 0.002). ICC values for all measurements ranged from 0.91 to 0.96, indicating excellent agreement between observers. No age-related differences were found (p = 0.835). The fibular head showed strong correlations with both epicondyles (r = 0.724 and r = 0.689). Conclusion: In healthy adults, the fibular head serves as a reliable radiologic landmark that may assist in joint line restoration during revision TKA, pending validation in clinical settings. The study also acknowledges its limitations of using plain radiographs and excluding the adductor tubercle as a reference point
The Geoheritage of Mount Ararat and its Vicinity: An Assessment of Geodiversity with a Focus on Glaciation and Mountaineering
No full textMount Ağrı (Ararat), located at the intersection of Turkey, Iran, and Armenia, is a region of exceptional geodiversity where iconic volcanic and glacial processes converge. In response, this study offers a systematic assessment of the geoheritage of Mount Ararat and its vicinity. By identifying, classifying, and prioritizing its key geosites, it aims to provide a structured knowledge base to support future conservation and sustainable geotourism initiatives. Using Brilha’s (2016) methodology, geosite and geomorphosite scores were assessed for sixteen key locations, supported by SWOT analysis, Last Glacial Maximum paleo-ELA estimations, and glacier retreat studies. High scientific and cultural values are evident in preserved glacial landforms, eruptive vents, and archaeological-historical features, while the mountain’s global symbolism and mountaineering appeal enhance its geoheritage potential. Strengths include the preservation of rare geomorphology, high geodiversity, and geotourism opportunities. Weaknesses highlight limited research, inadequate infrastructure, and environmental pressures from uncontrolled mountaineering and pack animals, as well as overtourism driven by excessive visitor numbers. Opportunities arise from potential geopark designation, cross-border scientific collaboration, and sustainable tourism initiatives, whereas threats involve climate-driven glacier retreat, natural hazards, and security restrictions in the border zone. The scoring results underline Ahura Valley, Summit Glaciers, and Noah’s Ark Site as priority geosites, with high scientific and cultural relevance but varying degradation risks. Overall, this assessment demonstrates that Mount Ağrı offers significant opportunities for integrating geoheritage conservation, scientific research, and sustainable geotourism, provided that management strategies address the identified environmental, political, and safety challenges
Evaluation of novel rapid colorimetric colistin resistance detection methods: Rapid Colistin Disc Elution Test in Klebsiella pneumoniae and Rapid Resazurin Disc Elution Test in Acinetobacter baumannii strains.
No full textChemical and biological evaluation of endemic <i>Origanum amanum</i> Post. essential oil
No full textOriganum amanum is an endemic species of the Lamiaceae, from the Amanous Mountains, T & uuml;rkiye. The plant samples were collected from Hatay, with soil samples from the same area. The chemical composition of the essential oil (EO) obtained by hydrodistillation was determined by gas chromatography-flame ionization detector and gas chromatography/mass spectrophotometry, simultaneously. In the essential oil, carvacrol was characterized as the main component at 63.7%. The in vitro antioxidant capacity of O. amanum oil was evaluated using ABTS center dot+ and DPPH center dot methods and antimicrobial activity was tested against Staphylococcus aureus ATCC 6538, Escherichia coli O157:H7 RSSK 234, Salmonella enterica subsp. enterica serovar Typhimurium ATCC 13,311, Candida krusei ATCC 6258, and Listeria monocytogenes ATCC 19111 pathogens. The in vitro 5-lipooxygenase (5-LOX) enzyme inhibition assay showed low anti-inflammatory activity. Good antioxidant capacity in the DPPH center dot assay, followed by inhibitory activity against S. aureus, E. coli, and S. Typhimurium pathogens, were observed
BİRLEŞME VE SATIN ALMALARIN FİRMA PERFORMANSINA ETKİLERİ: BORSAİSTANBUL'DA FAALİYET GÖSTEREN İMALAT SANAYİ FİRMALARI ÜZERİNE BİRARAŞTIRMA
No full text
