Texas Journal of Medical Science
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    Monitoring of patients with Cardiorenal syndromes

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    Cardiac and renal diseases often coexist and patients with cardiac and renal failure have high morbidity and mortality. Cardiorenal syndromes (CRSs) are disorders of the heart and kidneys whereby dysfunction in one organ may induce dysfunction in the other organ. Five subtypes of CRSs have been defined by the Acute Dialysis Quality Initiative Consensus Group. There is a need for early detection and monitoring of patients with CRSs. Biomarkers play a key role in the diagnosis and monitoring of acute myocardial infarction, chronic heart failure, and chronic kidney disease. In recent years, new biomarkers have been identified that may play a role in the early diagnosis of acute kidney injury. Herein, we review the use of serum and urine biomarkers in the diagnosis and management of CRSs. The established cardiac and renal biomarkers such as the cardiac troponins, natriuretic peptides, urine albumin, and creatinine, as well as the new renal biomarkers cystatin C and neutrophil gelatinase–associated lipocalin are reviewed in detail. The recent advances in assay methods, clinical studies, and recommendations in clinical guidelines are discussed. With advances in biomarker research, in future, perhaps a multimarker approach will become feasible to stratify the diagnosis of CRS for individualized treatment and prognosis

    Projection of HIV prevalence among individuals aged 15-49 years in Chile using Holt’s double exponential smoothing model

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    This study uses annual time series data of HIV prevalence among individuals aged 15-49 years for Chile from 1990 to 2020 to predict future trends of HIV prevalence over the period 2021 to 2030. The study utilizes Holt’s double exponential smoothing model. The optimal values of smoothing constants α and β are 0.6 and 0.1 respectively based on minimum MSE. The results of the study indicate that annual HIV prevalence among individuals aged 15-49 years will continue on an upward trend over the out of sample period. Therefore, we encourage authorities to scale up demand generation for all HIV services especially among key populations and vulnerable groups

    Family Spirituality Is A Criteria Of National Pride

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    This article talks about the sanctity of the family, traditions typical of Uzbek families, family etiquette among elementary school students. The rich historical, cultural and educational heritage, traditions and values of our people were discussed in the issues of education and morals. Also, based on the teachings of our great thinker, attention was paid to the most important issues of family relations, the duty of parents in the family and their responsible approach in this regard

    The Role Of Simulators In Final Exams At Medical Universities: Revolutionizing Assessment In Healthcare Education

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    The integration of simulators into final exams at medical universities is transforming the way student competence is assessed. These advanced tools, which include high-fidelity mannequins, virtual reality (VR) simulations, and patient interaction models, allow for more realistic, standardized, and objective evaluations of students' clinical skills and decision-making abilities. By simulating real-world clinical scenarios, simulators provide a safer, more controlled environment for assessing critical skills such as diagnosing, performing procedures, and patient communication. This approach not only enhances the fairness and consistency of assessments but also better prepares students for the challenges of real-world medical practice. While there are challenges, including high costs and faculty training requirements, the use of simulators in medical final exams represents a valuable advancement in medical education. As technology continues to evolve, simulators will play an increasingly central role in shaping the future of healthcare training and assessment

    The Application Of High-Tech Algorithms For Laparoscopic Cholecystectomy

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    Laparoscopic cholecystectomy (LC) is a surgical procedure frequently performed in benign gallbladder diseases since its description and has become the gold standard surpassing open cholecystectomy due to its numerous advantages. Like any new technique, adaptation problems were experienced in the early days of its application and complication rates were relatively high. In subsequent years, the evolution of minimally invasive surgery and the growing experience of surgeons have facilitated the application of LC and led to various modifications. This article aims to explore the evolution of cholecystectomy techniques, focusing on standard LC and over 50 modified techniques documented in the medical literatur

    Knee joint endoprosthetics for rheumatoid arthritis

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    Determination of the immediate outcomes of disease course, preparation for surgery and treatment during knee joint endoprosthetics of patients with rheumatoid arthritis

    Nutritiology And Proper Nutrition

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    This article delves into the field of nutritiology, aiming to provide a thorough understanding of proper nutrition and its impact on human health. Through an analysis of existing literature, the article explores dietary guidelines, the role of macronutrients and micronutrients, and the methods employed in nutritional research. The results section presents key findings, leading to a discussion on the implications for health. The article concludes with insights and suggestions for individuals seeking to enhance their nutritional well-bein

    Selection Of Treatment Methods For Patients With Multiple Fractures Of Lower Extremity Bones

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    The aim of the study is to improve the results of treatment of patients with multiple lower extremity fractures by optimizing complex diagnostics and minimally invasive methods of external and internal fixation. The experience of treating 220 patients with multiple fractures of the long bones of the lower extremities in the clinic of the Republican Scientific and Practical Center of Traumatology and Orthopedics from 2016 to 2022 is presented

    Congenital dislocation of shin bones: treatment tactics

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    Purpose is to analyze the treatment of congenital dislocation of shin splint

    Diagnosis Of Intrauterine Pneumonia in Premature Infants

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    The gestational age of the subjects was 22–36 weeks. Tensiometric blood parameters in the group of premature newborns with VUP and RDS suggest that they have congenital intrapartum pneumonia. When Ds2 < 4.2 × 103 N/m and k2 > 3.3 × 103 s–1, it can be stated that a premature newborn with respiratory disorders has VUP. We recommend using these indicators in the early and differential diagnosis of intrauterine pneumoni

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