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SMART O2: Adjusting oxygen to patient needs. An observation study of oxygen administration to critically ill children admitted to Holy Innocents Children’s Hospital in Mbarara, Uganda
No full textDataset Description: This dataset contains materials from Smart O2 study. Materials include the study protocol and associated documents.
Background: Pneumonia, sepsis, and diarrheal diseases are the leading cause of critical illness and death in children worldwide. A significant proportion of these deaths can be prevented by supplemental oxygen therapy. Children in low- and middle-income countries (LMICs) bear a disproportionately higher burden of critical illness and death due to pneumonia, sepsis and diarrheal diseases but also have inequitable access to medical oxygen. While many efforts are underway to increase oxygen production capacity in underserved areas, this must be balanced with efforts to prevent waste and optimize oxygen utilization (oxygen conservation).
To address the challenge of oxygen conservation, we aim to develop and evaluate a system that will allow us to adjust oxygen flow rates based on pulse oximetry feedback. This study involves the first phase: we conducted an observational study to collect baseline data from a cohort of 200 critically ill children receiving oxygen treatment at Holy Innocents Children’s Hospital. We will use this data to develop and validate a clinical algorithm and decision support system (Smart O2) for oxygen administration based on models of optimized oxygen utilization.
Methods: Trained research nurses reviewed all children admitted for oxygen therapy within 72 hours of admission. Eligible children were those admitted to the hospital ward and prescribed nasal oxygen therapy by their treating healthcare provider due to low oxygen saturation (SpO₂) at the time of presentation. Children who received oxygen for seizures or other conditions in which oxygen is administered despite normal SpO2, were recommended for exclusion by a clinician for any reason, did not provide verbal assent, or had guardians who did not provide consent were excluded. Data collection for all enrolled children began immediately upon initiation of oxygen therapy. A deferred consent process was used to avoid delays in starting treatment, where consent was obtained when the child was clinically stable after oxygen therapy initiation. Consent was obtained the following day for children admitted overnight. If either the caregiver or the child declined participation, monitoring and oxygen therapy continued as per hospital protocol, but data collection was stopped, and all collected data were deleted.
Nurses collected clinical characteristics and clinical data variables required for the study using a paper-based case report form (CRF). Deidentified data from the CRF were entered into a Research Electronic Data Capture (REDCap) project.
The study used three data collection setups. One setup included a Masimo Root device with a Masimo ISA OR+ side-stream oxygen analyzer and a Masimo Radical-7 monitor. The other two setups used Masimo Rad-97 Pulse CO-Oximeters. All setups were equipped with custom-built in-line electronic flow meters. A custom Android application was used to record and store data in real time. The data collection devices captured physiological and system-level variables.
Ethics Declaration: Ethics approval for this study was obtained from the institutional review boards at Makerere University School of Public Health in Uganda (SPH-2023-453), the Uganda National Council of Science and Technology (HS3390ES), and the University of British Columbia Children’s and Women’s Research Ethics Board in Canada (H23-01811).NOTE for restricted files: If you are not yet a CoLab member, please complete our membership application survey to gain access to restricted files within 2 business days.
Some files may remain restricted to CoLab members. These files are deemed more sensitive by the file owner and are meant to be shared on a case-by-case basis. Please contact the CoLab coordinator at [email protected] or visit our website
Replication Data for: A Principal Component Analysis of the Post-Secondary Student Stressors Index in a Sample of Ontario Students
No full textThis data is replication material for the paper: A Principal Component Analysis of the Post-Secondary Student Stressors Index in a Sample of Ontario Students. Authors: Kuburi, Sarah; Wang, BingSen; Hamza, Chloe A.; Linden, Brook
IEA Natural Gas Information Statistics. OECD - Natural Gas exports by destination, 1960-2022
No full textThis table contains data on natural gas exports by origin for 38 OECD countries and 14 European non-OECD countries from 1960 to 2023, with 2023 data being provisional. Country aggregates for OECD Total, OECD Americas, OECD Asia Oceania, OECD Europe, IEA Total, EU27, and EU28 are also included. Data are available for total trade, pipeline trade, and LNG trade. Data are in million cubic metres (MCM) and Terajoule (TJ)
Enquête sur la population active, novembre 2024 [Canada]
No full textL'Enquête sur la population active (EPA) fournit des estimations de l'emploi et du chômage. Parmi les principales séries de données économiques mensuelles, les estimations de l'EPA sont les premières à être rendues publiques, les résultats de l'enquête étant diffusés 10 jours seulement après la fin de la collecte. Les données de l'EPA sont utilisées pour produire le très connu taux de chômage ainsi que d'autre indicateurs de base du marché de travail tel que le taux d'emploi et le taux d'activité. Les données de l'EPA sont utilisées pour produire le très connu taux de chômage ainsi que d'autre indicateurs de base du marché de travail tel que le taux d'emploi et le taux d'activité. En plus, l'EPA procure également des estimations de l'emploi selon l'industrie, la profession, les secteurs publics et privés, le nombre d'heures travaillées et davantage. Il est possible de croiser ces séries selon une variété de caractéristiques démographiques. Des estimations sont diffusées pour le Canada, les provinces, les territoires et pour plusieurs régions infraprovinciales. Pour les employés, des données sur les salaires, la couverture syndicale, la permanence de l'emploi et la taille de l'établissement sont également disponibles.
Ces données sont utilisées par les différents paliers de gouvernements pour évaluer et planifier les programmes d'emploi au Canada. Les taux de chômage régionaux sont utilisés par Emploi et Développement social Canada pour déterminer l'admissibilité au régime d'assurance-emploi, de même que le niveau et la durée des prestations pour les personnes qui vivent à l'intérieur d'une région d'assurance-emploi donnée. Les données sont utilisées par les analystes du marché du travail, les économistes, les consultants, les planificateurs, les prévisionnistes ainsi que les universitaires et ce, autant du secteur public que privé.
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Early Warning and Rapid Public Health Response to Prevent COVID-19 Outbreaks in Long-term Care Facilities (LTCF) by Monitoring SARS-CoV-2 RNA in LTCF Site-specific Sewage Samples and Assessment of Antibodies Response in this Population [SSSIS, study data contributed to the CITF Databank]
No full textBackground:Residents of Canadian long-term care facilities (LTCF) experience challenges with social distancing and the movement of staff between the facility and their communities, which increases their vulnerability to COVID-19.
Aims of the CITF-funded study: The SSSIS study aimed to 1) investigate and conduct a cost-benefit analysis on the use of a site-specific sewage surveillance of SARS-CoV-2 as an early warning system to prevent outbreaks in LTCFs; 2) study the antibody response of residents and staff in LTCFs; and 3) evaluate the execution of commercial assays aimed to detect vaccine-induced antibodies and the correlation with neutralizing antibody responses.
Methods: For Part I of this study where the unit of analysis was long-term care facilities, sewage samples were monitored semiweekly: if the sample tested negative for SARS-CoV-2, no action was taken, but positive results warranted an investigation if necessary. Part II was a cohort study was conducted in a different set of LTCF, where residents and staff were recruited from the LTCF Associations across Edmonton region of Alberta. Participants completed a questionnaire and provided a blood sample (venipuncture or DBS) at baseline and at follow-ups pre-vaccine, pre-second dose, and 3-, 6-, 12-, and 18-months post second dose.
Summary of dataset contents: For Part I of this study, a total of 2,936 sewage samples were collected from 12 sites between Jan 2021 and May 2023: 36% (1,058) of the sewage samples were tested positive for SARS-CoV-2. For Part II of this study, the datasets include 364 participants (241 staffs and 123 residents) who completed a questionnaire between Feb 2021 and Aug 2021. All participants provided one or more blood samples at baseline and during follow-up visits up to Dec 2022. A total of 966 blood samples were collected. Variables include data in the following areas of information: demographics (age, gender), exposure risk factors (dining place for residence, working site for staff), longitudinal follow-up for COVID infections (COVID test) and vaccination, and serology
3-step Starter case for teaching
No full textDemo of a generic starter, containing a bunch of commonly used tweaks, as a template for future cases.
Has starting Annotation field comment, a sample Question, a help Section with TW5 generic help file and RTB button, and a generic Feedback note for the Session Report
Census of Population, 2021 [Canada]: Special Interest Profiles
No full textThe Special Interest Profiles present data for specific census topics and population groups according to selected demographic, cultural, and socio-economic characteristics. These detailed 'profile-type' tables expand the analytical depth of basic census information. This product presents 2021 Census of Population characteristic data for nine separate profiles of interest, including:
age
ethnic origin
first official language
immigration
income distribution by income source
mother tongue
poverty, COVID-19 benefits, high income
religion
visible minority
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Replication data: Factors associated with milk pregnancy-associated glycoprotein levels in pregnant dairy cows and their interaction with milk yield at test day
No full textThis Dataverse contains the R script used for the associated articl
Anti-racism and anti-oppression readings. Supplement to: Practicing slow dwelling as an approach to anti-oppressive journal editorship: a case study of CAML Review/Revue de l’ACBM, the journal of the Canadian Association of Music Libraries
No full textThis bibliography includes the materials that the CAML Review editorial team read in their anti-racism and anti-oppression meetings from 2020 to 2024. These semi-annual meetings began in 2020, and were the site of critical work around antiracism, especially in scholarly publishing. This bibliography also contains a list of recent resources addressing racism in music studies