Repositorio Institucional ITBA
Not a member yet
2611 research outputs found
Sort by
Dopamine D1/D5 receptors in the restrosplenial cortex are necessary to consolidate object recognition memory
Get PDF"The retrosplenial cortex (RSC) has been widely related to spatial and contextual memory. However, we recently demonstrated that the anterior part of the RSC (aRSC) is required for object recognition (OR) memory consolidation. In this study, we aimed to analyze the requirement of dopaminergic inputs into the aRSC for OR memory consolidation in male rats. We observed amnesia at 24-h long-term memory when we infused SCH23390, a D1/D5 dopamine receptors antagonist, into aRSC immediately after OR training session. However, the same infusion had no effect on OR short-term memory. Then, we analyzed whether the ventral tegmental area (VTA) is necessary for OR consolidation. VTA inactivation by intra-VTA administration of muscimol, a GABAA agonist, immediately after
an OR training session induced amnesia when animals were tested at 24 h. Moreover, we observed that this VTA inactivation-induced amnesia was reversed by the simultaneous intra-aRSC delivery of SKF38393, a D1/D5 receptor agonist. Altogether, our results suggest that VTA dopaminergic inputs to aRSC play an important modulatory role in OR memory consolidation.
Non-linear susceptibility to interferences in declarative memory formation
Get PDF"After encoding, memories go through a labile state followed by a stabilization process known as consolidation. Once consolidated they can enter a new labile state after the presentation of a reminder of the original memory, followed by a period of re-stabilization (reconsolidation). During these periods of lability the memory traces can be modified. Currently, some studies show a rapid stabilization after 30 min, while others show that stabilization occurs after longer periods (e.g. > 6 h). Here we investigate the effect of an interference treatment on declarative memory consolidation, comparing distinct time intervals after
acquisition. On day 1, participants learned a list of non- syllable pairs (List 1). 5 min, 30 min, 3 h or 8 h later, they received an interference list (List 2) that acted as an amnesic agent. On day 2 (48 h after training) participants had to recall List 1 first, followed by List 2. We found that the List 1 memory was susceptible to interference when List 2 was administered 5 min or 3 h after learning but not when it was administered 30 min or 8 h after. We propose the possibility that this rapid memory protection could be induced by a fast and transient neocortical integration. Our results open a discussion about the contribution of molecular and systemic aspects to memory consolidation.
Park King: la mejor experiencia al estacionar
Get PDF"El presente proyecto consiste en el desarrollo de una unidad de negocio dentro de una empresa ya existente en el mercado, MVL Consulting, que desarrollará una aplicación digital denominada Park King basada en economía colaborativa sumada a tecnología de geolocalización con el objetivo de facilitar el proceso de estacionamiento en las grandes ciudades."Tesis en Dirección Estratégica y Tecnológica (maestría) - Instituto Tecnológico de Buenos Aires, Buenos Aires, 202
Analysis of the impact of artificial networks in system-level EMC tests
No full textThe impedance of an Off-The-Shelf Artificial Network (OTS-AN) and a custom made High-Frequency Artificial Network (HF-AN) were analysed and compared. It is showed that in order to meet the requirements of automotive standards, such as Bulk Current Injection (BCI) from ISO 11452-4 as well as both Conducted and Radiated Emissions (CE, RE) from CISPR 25, the HF-AN is needed. System-level circuit simulations were run using S-parameters for quantifying the impact of these two models in the previously mentioned EMC tests. Above 50 MHz, up to 3.5 dB and 4.3 dB differences were found on the transferimpedance of CE and in the Common-Mode to Differential-Mode conversion of BCI, respectively. On the other hand, in RE the OTS-AN leaded to an overestimation of the emission profile in the 300 MHz and 800 MHz band as high as 5.3 dB. Besides that, it is showed that the OTS-AN behaves as a source of non-constant uncertainty, specially above 50 MHz. Finally, the issues in terms of reproducibility, repeatability and accuracy that arise from the non-RF connectors in the OTS-AN are discussed and a metric for test-bench comparison and validation is proposed
"Somnus": diseño y desarrollo de un sistema modular para polisomnografía
No full text"El presente proyecto final de carrera consta del diseño y desarrollo de un sistema para polisomnografía con una arquitectura versátil que puede ser adaptada para su uso en distintas líneas de investigación. La misma se basa en un esquema modular que permitirá, en un futuro, reemplazar, agregar o quitar bloques según se crea conveniente."Proyecto final Bioingeniería (grado) - Instituto Tecnológico de Buenos Aires, Buenos Aires, 202
Dynamical models in neuroscience from a closed-loop control perspective
Get PDF"Modifying neural activity is a substantial goal in neuroscience that facilitates the understanding of brain functions and the development of medical therapies. Neurobiological models play an essential role, contributing to the understanding of the underlying brain dynamics. In this context, control systems represent a fundamental tool to provide a correct articulation between model stimulus (system inputs) and outcomes (system outputs). However, throughout the literature there is a lack of discussions on neurobiological models, from the formal control perspective. In general, existing control proposals applied to this family of systems, are developed empirically, without theoretical and rigorous framework. Thus, the existing control solutions, present clear and significant limitations. The focus of this work is to survey dynamical neurobiological models that could serve for closed-loop control schemes or
for simulation analysis. Consequently, this paper provides a comprehensive guide to discuss and analyze control oriented neurobiological models. It also provides a potential framework to adequately tackle control problems that could modify the behavior of single neurons or networks. Thus, this study constitutes a key element in the upcoming discussions and studies regarding control methodologies applied to neurobiological systems, to extend the present research and understanding horizon for this field.
Unidad de isomerización
No full text"La finalidad de este documento es evaluar el contexto bajo el cual se diseñará una unidad de isomerización de naftas para su instalación y puesta en marcha. Se evaluará la viabilidad del proyecto, el cual será llevado a cabo en las afueras de la ciudad de Luján de Cuyo, provincia de Mendoza, Argentina. El objetivo del mismo es aumentar considerablemente el octanaje de la nafta para poder proveer al mercado un producto de mayor calidad y mayor valor agregado."Proyecto final Ingeniería Industrial (grado) - Instituto Tecnológico de Buenos Aires, Buenos Aires, 202
El rol del movimiento ambiental juvenil argentino en la transición al desarrollo sostenible: análisis desde una perspectiva de innovación
Get PDF"El presente trabajo analiza el movimiento ambiental juvenil argentino y destaca el rol específico y diferenciado que este actor cumple en la transición al modelo de desarrollo sostenible que demanda el contexto actual."Tesis Gestión Ambiental (maestría) - Instituto Tecnológico de Buenos Aires - Buenos Aires, 202
Estudio de prefactibilidad de un cultivo de frutillas en hidroponia
No full textSe desarrolla el estudio de prefactibilidad de un cultivo de frutillas en hidroponía. La hidroponía es una técnica de cultivo en ambiente controlado que consiste en no utilizar el suelo y proveer los nutrientes que necesita la planta a través del agua. Cuenta con múltiples ventajas ambientales, productivas y logísticas, especialmente para la frutilla por los cuidados que requiere, el valor que gana según la calidad y la escasez de oferta durante la mayor parte del año.
En primer lugar, se realiza un estudio de mercado, seguido de un estudio de ingeniería, donde se detallan aspectos técnicos del proyecto. En tercer lugar, se lleva a cabo un estudio económico financiero, en el cual se evaluará la rentabilidad del proyecto y por último, se realiza un estudio de los riesgos implicados con el objetivo de mitigarlos
Trabajo final integrador: propuesta técnica de desarrollo de Yacimiento "La Esperanza", equipo B - grupo 4
Get PDF"El presente informe constituye una oferta técnica que tiene por objetivo participar de la licitación pública que se realizará para la adjudicación de los derechos de explotación de un yacimiento convencional de gas y condensado, denominado “La Esperanza”, ubicado en la Cuenca Neuquina en la provincia de Neuquén con un horizonte temporal de 25 años."Trabajo Final Economía de Petróleo y Gas Natural (especialización) - Instituto Tecnológico de Buenos Aires, Buenos Aires, 202