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Femvertising Yaklaşımla Femtrafik Mücadelesi Üzerine Bir İnceleme
No full textAraştırmada trafikteki kadınların güçlü imajlarının ön plana çıkarılması hedeflenmiş, femvertising desen kullanılmıştır. Otomobil imgesindeki agresif-eril erkeksi imajlar eleştirilmiş, femvertising yaklaşımla güçlü ve feminen imajlar öne çıkarılmıştır. Teorik çerçeve postmodern feminist kurama dayanmakta; örnek grubunu Porshe Taycan otomobil reklam filmi ve kadın sürücüler oluşturmaktadır. Reklam filmi görsellik, üretilen dil, mekan bağlamlarıyla kesitsel olarak incelenmiş; ardından kadın sürücülerden yarı yapılandırılmış mülakatla veri toplanmıştır. Tematik analizin yapıldığı çalışmada Braun ve Clarke ile Coutés’ın teknikleri kullanılmıştır. Bulgularda trafikteki kadına yönelik toplumsal cinsiyet yargıları eleştirilmekte; kadınların erkeklerden daha iyi araç kullandığı görülmektedir. Kadınların gündelik yaşamlarında ve medyada trafikteki erkeklerle mücadele ettikleri söylenebilir. Erkek sürücüler trafikteki kadınlara kendilerini güvensiz hissettirmekte; kendi riskli davranışlarına meşru zemin oluşturmaktalardır. Trafiğin agresif hegemonik yapısı kadınlara güvenli otomobili tercih ettiren unsurlardandır. Otomobilin kadınlar için özgürlük kapsamlı feminist değeri vardır. Trafikte kadının güçlü temsili için femtrafik kavramı öne sürülmüştür. Trafikte kadına yönelik ayrımcılığa karşı toplumsal farkındalığın geliştirilmesi, akademik ve kurumsal çalışmaların artırılması femtrafik hareket için önemlidir.</p
Coherence-driven quantum battery charging via autonomous thermal machines: Energy transfer, memory effects, and ergotropy enhancement
No full textIn this work, we study a hybrid quantum system composed of a quantum battery and a coherence-driven charger interacting with a Quantum Autonomous Thermal Machine (QATM). The QATM, made of two qubits, each coupled to Markovian bosonic thermal reservoirs at different temperatures, acts as a structured environment that mediates energy and coherence between the charger and the battery. By applying a coherent driving field on the charger, we investigate the coherence injection effect on the dynamics, including non-Markovianity, power of charging, coherence storage, and ergotropy. We show that the QATM filters the decoherence induced by the thermal baths and induces non-Markovian memory effects due to correlation backflow. Our results demonstrate that coherence driving enhances the battery's ergotropy; coherence driving raises the maximum ergotropy by approximately 40 % compared to the case without coherence driving, and the power of charging by preserving the internal energy of the charger
Novel 8-hydroxyquinoline compounds used to inhibit mild steel corrosion in the presence of hydrochloric acid 1.0 M: an experimental and theoretical electrochemical study Nouveaux composés d’hydroxyquinoléine-8 utilisés pour inhiber la corrosion de l’acier doux en présence d’acide chlorhydrique 1.0 M: une étude électrochimique expérimentale et théorique
No full textThe present study examined the corrosion inhibition property of two derivatives of 8-hydroxyquinoline, namely diethyl 1,1-(4-(4-chlorophenyl)-1-((8-hydroxyquinoline-5-yl)methyl)-2, 6-dimethyl-1, 4-dihydropyridine-3,5-diyl) diethanone (P1) and diethyl 1,1-(4-(4-bromophenyl)-1-((8-hydroxyquinoline-5-yl)methyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl)diethanone (P2). against mild steel (MS) degradation in 1.0 M hydrochloric acid (HCL) solution. The study was carried out using electrochemical techniques such as dynamic potential polarisation (DPP) and impedance spectroscopy (EIS) at different temperatures (298–328 K). Inhibition efficiency (IE %) increased with inhibitor concentration, reaching 97.0% for P1 and 91.8% for P2 at 10−3 M (298 K). Impedance measurements indicated that charge transfer resistance (Rct) increased, while double-layer capacitance (Cdl) decreased with increasing concentration of P1 and P2. Analysis of the polarisation curves shows that P1 and P2 act as mixed-type inhibitors. According to the Langmuir isotherm and thermodynamic parameters, P1 and P2 are adsorbed onto the mild steel surface by chemical interactions. The SEM/EDX analysis results revealed the formation of an adsorption film on MS. DFT calculations show that free heteroatom doublets of oxygen (O) and nitrogen (N) promote electron sharing between the molecules studied and the steel surface. Data from theoretical methods (DFT) confirm the experimental results
Evidence for KISS-1 nuclear translocation and PI3K/AKT signaling in the ultrastructurally and morphometrically analyzed human endometriosis
No full text Background Endometriosis is a common estrogen-dependent disease marked by ectopic endometrial growth. Although the PI3K/AKT and kisspeptin pathways are known to regulate endometrial homeostasis, their interplay in disease progression remains unclear. This study investigated the relationship between nuclear Kisspeptin (KiSS-1) localization and PI3K/AKT pathway activity in endometriotic tissues, focusing on stage-specific cellular alterations. Methods In this prospective study, control, eutopic and ectopic endometrial biopsies were collected from 27 women (18 controls, 9 with ovarian endometriosis). Histopathological assessments were performed using JB4 embedding, immunofluorescence, and transmission electron microscopy. Morphometric analyses were used to quantify structural alterations. Results In both eutopic and ectopic endometrium from patients with endometriosis, PI3K and AKT expression levels were significantly increased, whereas KiSS-1 expression was reduced and showed nuclear localization in a subset of cells. TEM analysis revealed features consistent with cellular stress, including autophagy-related vesicles, mitochondrial structural disruption, and alterations in nuclear architecture. Morphometric evaluation demonstrated a fibrotic remodeling in ectopic tissue. Specifically, glandular volume decreased, while stromal matrix content increased (p &lt; 0.05). Conclusion These findings suggest a mechanistic link between PI3K/AKT signaling and nuclear KiSS-1 translocation as an adaptive response to chronic hypoxia and inflammation in endometrial cells. This interaction may regulate survival, proliferation, and fibrotic remodeling processes characteristic of endometriosis. This integrated ultrastructural and molecular analysis provides novel insights into the pathophysiological role of nuclear KiSS-1 and its potential as a diagnostic and therapeutic target in endometriosis. </jats:sec
Bioactive properties of Vicia canescens subsp. variegata (Willd.) P.H. Davis, Fabaceae: antioxidant, antiparkinsonian and relevance to food and agriculture use
No full textBACKGROUND: Various Vicia species belonging to the Fabaceae family are known to be used in different parts of the world both in human nutrition and as animal feed, and also have pharmacological potential in the prevention and treatment of various diseases. With this perspective, in the present study, the possible antiparkinsonian effects of extracts prepared from Vicia canescens subsp. variegata were investigated in cell culture and on 6-hydroxydopamine (6-OHDA)-induced Parkinson's model rats. The effects of the plant on the pathophysiology of Parkinson's disease were evaluated by biochemical and histopathological analyses; in addition, the structures of the compounds isolated from the active extracts were elucidated and the in vitro antioxidant and antiparkinsonian activities of these compounds were determined. RESULTS: Methanol and n-butanol extracts prepared from the aerial parts of V. canescens subsp. variegata showed significant antiparkinsonian effects both in cell culture and in a rat model. Histopathological and biochemical analyses were also parallel to in vivo experiments. As a result of the isolation studies, six flavonol glycosides were obtained from the plant, and their antioxidant capacities as well as antiparkinsonian effects were subsequently evaluated. The highest biological effect was observed in quercetin-3-O-α-l-rhamnopyranoside (quercitrin, VCB-3). CONCLUSION: In the light of the studies, the antiparkinsonian effects of V. canescens subsp. variegata was evaluated. It was seen that they prevented neurodegeneration and the oxidative stress that occurred, and the most effective compounds were determined. Two new compounds named viciacoside A and B have been added to the literature as a result of this research. © 2025 Society of Chemical Industry
Strategic design and mechanistic unveiling of Ni-based S-scheme heterojunctions for efficient CO2 photoreduction to C1 products: Coordination chemistry, spectroscopic evidence, and future directions
No full textTackling the rising anthropogenic CO2 level aligns directly with the United Nations Sustainable Development Goals (SDGs), exclusively SDG 7 (Affordable and Clean Energy) and SDG 13 (Climate Action). The CO2 photoreduction into C1 products, i.e., CO and CH4, provides a favorable route to reduce greenhouse gas emissions. Among various modification strategies, the S-scheme heterojunction construction has a bright shine in the material chemistry field owing to its enhanced charge carrier separation efficiency, minimized charge carrier recombination, strong redox ability, and enhanced photocatalytic performance. The review significantly explores the recent advancements in Ni-based S-scheme junctions for CO2 reduction, highlighting their interfacial charge transfer kinetics to achieve high selectivity. Firstly, the general CO2 photoreduction mechanism was introduced to provide essential background knowledge. The article then probes the development of S-scheme mechanism and various classifications of S-scheme heterojunctions based on Ni-LDH, NiO, Ni(OH)2, Ni-MOF, NiS, Ni2P, etc., integrated with suitable semiconductors. Ni-based photocatalysts are a potential component within S-scheme heterojunctions because of their strong stability, suitable band potentials, cost-effectiveness, and earth-abundant nature. The advanced spectroscopic techniques, including DFT, KPFM, and ISI-XPS, are highlighted to validate the S-scheme charge transfer route. Moreover, the CO2 reduction pathways were discussed with the primary focus on CO2 adsorption, activation, intermediate stability, and C1 product selectivity. Finally, the article outlines the respective challenges and future prospects in the field with the hope that this work offers strategic insight for developing photocatalytic CO2 reduction technologies, supporting the pursuit of global carbon neutrality goals
Short-Term Inspiratory Muscle Training Enhances Functional and Metabolic Health in Older Adults
No full textBackground: Age-related declines in respiratory muscle strength and ventilatory efficiency can impair functional capacity and metabolic health in older adults. Inspiratory muscle training (IMT) has been proposed as a practical intervention to counteract these changes, yet its systemic effects remain unclear. This study aimed to examine the effects of short-term IMT on functional capacity, diaphragm thickness, and liver tissue characteristics in healthy elderly men. Methods: Thirty community-dwelling men aged 60–80 years were randomly assigned to an IMT or control group. The IMT group performed four weeks of breathing exercises using a POWERbreathe® device at 40% of maximal inspiratory pressure, with a weekly 10% increase in pressure. Pre- and post-intervention assessments included the six-minute walk test (6MWT), diaphragm thickness and liver density via computed tomography, and quality of life (QoL; SF-12). Results: Four weeks of inspiratory muscle training significantly improved diaphragm thickness (11.7%), fatty liver density (FLD) (+16.7%), and six-minute walk performance (+5.3%), with large time × group effects favoring the IMT group. While the physical quality of life showed modest, comparable improvements, mental health outcomes demonstrated a moderate, time-dependent improvement without a significant group-by-time interaction. Conclusions: Short-term IMT improved diaphragmatic function and functional capacity in older men and was associated with favorable changes in a liver-related biomarker; however, given that only a single liver-related metric was assessed, these findings should not be interpreted as evidence of overall improvements in liver health.</p