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Döngüsel Ekonomi Politikalarının Gelişimi: Avrupa Birliği ve Çin Halk Cumhuriyeti İncelemesi
Streptococcus mutans BİYOFİLMİNİN GRADE-IV TİTANYUM İMPLANT YÜZEYLERE TUTUNMA KAPASİTESİ
Amaç: Peri-implant hastalıklar, dental implantlarda primer etiyolojik faktör olan bakteriyel biyofilme karşı duyarlı bir konak cevabı ile meydana gelen enflamatuvar hastalıklardır. Biyofilmler ağız içerisindeki mikroorganizmaların yüzeylere tutunarak oluşturdukları ekzopolisakkarit matriks yapılarıdır. Streptococcus mutans (S. mutans) oral florada biyofilm oluşturan temel ağız içi patojenlerin başında yer almaktadır. Dental implantların yüzey özellikleri bakterilerin biyofilm davranışında kritik bir role sahiptir. Bu nedenle bu çalışmada Grade-IV titanyum (Ti) disklerde S. mutans biyofilminin tutunma kapasitesi in-vitro olarak değerlendirilmiştir.Gereç ve Yöntem: Biyofilm oluşumu kristal viyole-mikrotitre plak yöntemi ile değerlendirilmiştir. Çapı 2 mm, kalınlığı 1 mm olan Grade-IV saf Ti pürüzlü yüzey diskler kullanılmıştır. Pozitif kontrol amacıyla %2-sükrozlu BHI broth besiyerinde üremiş S. mutans ATCC 25175 inokulumu (PK-1) ve biyofilm oluşumunu destekleyen cam yüzey materyalleri (PK-2) kullanılmıştır. Negatif kontrol amacıyla ise bakteri içermeyen %2-sükrozlu BHI broth besiyeri kullanılmıştır. Her bir disk kuyucuğu ve kontrol kuyucukları üçer tekrarlı olarak çalışılmıştır. Biyofilm tutunma kapasiteleri her üç kuyucuğun 570nm sahip oldukları OD değerlerinin ortalamaları belirlenerek, kontrol kuyucukları ile yapılan analizler sonucu belirlenmiştir.Bulgular: Ti-disklerin biyofilm tutma kapasitesi S. mutans’ ın kuyucuk cidarında oluşturduğu biyofilm tabakası olan PK-1’e göre kıyaslandığında, disklerdeki biyofilm tutunma kapasitesinin anlamlı olarak fazla olduğu belirlenmiştir. Biyofilm tutma kapasitesi kesin olan cam yüzeylerde tutunan biyofilm kapasitenin (PK-2) de yüksek olduğu ve Ti-disklerle cam yüzeyler arasında biyofilm tutma kapasitesi açısından anlamlı farklılık olmadığı tespit edilmiştir. Ti-disklerin yüzey özelliklerinin, pratik uygulamada osseointegrasyonu desteklemek için tercih edilen pürüzlü yüzey özelliklerine benzer şekilde tercih edilmesine bağlı olarak S. mutans biyofilminin tutunma kapasitesinin yüksek olarak belirlenmiştir.Sonuç: Dental implant materyallerinin osseointegrasyona zarar vermeden, biyofilm tutma kapasitesinin az olması dental implantların sağlığının korunması açısından oldukça önemlidir. Grade-IV pürüzlü yüzey özelliklerine sahip Ti-disklerin S. mutans biyofilm tutma kapasitesinin yüksek olmasının; bu konuda, farklı yüzey özelliklerine sahip Ti-materyaller ile yapılacak ileriki araştırmaların bulguları ile karşılaştırılması, yüzey özelliklerinin biyofilm tutma kapasitesine etkisinin değerlendirilmesi açısından gereklidir.Peri-implant diseases are inflammatory diseases caused by a susceptible host response to bacterial biofilm, which is the primary etiological factor in dental implants. Biofilms are exopolysaccharide matrix structures formed by microorganisms in the mouth by adhering to the surfaces. Streptococcus mutans (S. mutans) is one of the main oral pathogens that form biofilms in the oral flora. The surface properties of dental implants play a critical role in the biofilm behaviour of bacteria. Therefore, in this study, the adhesion capacity of S. mutans biofilm on Grade-IV titanium (Ti) discs was evaluated in vitro.Materials and Methods: Biofilm formation was evaluated by crystal violet-microtiter plate method. Grade-IV pure Ti rough surface discs with a diameter of 2 mm and a thickness of 1 mm were used. S. mutans ATCC 25175 inoculum grown in 2% sucrose BHI broth medium (PK-1) and glass surface materials (PK-2) supporting biofilm formation were used as positive controls. For negative control, 2% sucrose BHI broth medium without bacteria was used. Each disc well and control wells were run in triplicate. Biofilm adhesion capacities were determined by averaging the OD values at 570nm of the three wells and analysed with control wells.Results: When the biofilm adherence capacity of Ti-discs was compared to PK-1, the biofilm layer formed by S. mutans on the well wall, it was determined that the biofilm adherence capacity on the discs was significantly higher. It was determined that the biofilm capacity (PK-2) retained on glass surfaces with a certain biofilm retention capacity was also high and there was no significant difference between Ti-discs and glass surfaces in terms of biofilm retention capacity. The adhesion capacity of S. mutans biofilm was determined to be high due to the preference of the surface properties of Ti-discs similar to the rough surface properties preferred to support osseointegration in practical application.Conclusion: The low biofilm retention capacity of dental implant materials without damaging osseointegration is very important for maintaining the health of dental implants. The high S. mutans biofilm retention capacity of Ti-discs with Grade-IV rough surface properties should be compared with the findings of future studies with Ti-materials with different surface properties in order to evaluate the effect of surface properties on biofilm retention capacity.</p
The Effects of Artificial Intelligence on Logo Design in Terms of Innovation, Originality and Functionality in Graphic Design Yapay Zekânın Grafik Tasarımda Yenilik, Özgünlük ve İşlevsellik Açısından Logo Tasarımı Üzerindeki Etkileri
The subject of the research is to examine the effects of artificial intelligence technologies on logo design in graphic design. The study was conducted using comparative analysis, literature review and logical reasoning techniques within the scope of qualitative research methods. These approaches have been selected to examine the effects of artificial intelligence on graphic design and the effects of technological developments on artistic expression and the role of designers and have been limited within the scope of literature and studies analyzed based on the obtained data and theoretical frameworks. The aim of the research is to conceptually discuss the interaction between artificial intelligence and graphic design and to provide insights on the effects of this interaction on designer identity and artistic expression. The findings of the research reveal that artificial intelligence technologies create multifaceted effects on both creative processes and the quality of outputs in the field of graphic design. These effects have been comprehensively evaluated in terms of their positive and negative aspects. The results showed that artificial intelligence technologies affect graphic design processes and reshape the creative and technical approaches of designers. This shaping has led to significant changes both in the professional practices of designers and in the general functioning of the graphic design sector. These changes include enabling designers to work faster and more efficiently in their creative processes, providing more focus and innovation through the automation of repetitive tasks, having wider creative opportunities with the development of design tools, and meeting customer expectations more quickly and effectively
Low-Lying Excited States in Even-Even Nuclei from Artificial Intelligence Methods
Information about the first excited 2+, 4+ and 6+ energy levels of atomic nuclei have an important place in nuclear structure studies as it contains a lot of information. Therefore, determining these energy levels with high accuracy allows obtaining more accurate information about the nucleus. In addition to being obtained experimentally, these energy levels can also be calculated with various theoretical models. In this study, we worked on predicting these energy levels with high accuracy by machine learning with existing experimental data using artificial intelligence approaches. According to the results of the study in which we used five different artificial intelligence approaches, we found that these alternative approach models are suitable for this purpose. We compared the obtained results with existing experimental data in the literature and with each other
Investigation of the Effect of Reiki on Pain, Fatigue, and Itching in Hemodialysis Patients: Randomized Controlled Trial
Introduction: The management of symptoms associated with hemodialysis, which adversely affect patients, increases their quality of life. Complementary integrative therapies such as Reiki are used in symptom management. This study aimed to investigate the effects of Reiki on pain, fatigue, and itching in hemodialysis patients. Methods: The study had a randomized controlled design and was conducted in three dialysis centers with a total of 74 hemodialysis patients, 37 in the intervention group, and 37 in the control group. A total of 10 sessions of Reiki were administered to the patients in the intervention group twice a week for 5 weeks, while the patients in the control group received routine hemodialysis treatment. The data of the study were collected using the Patient Identification Form, the Patient Clinical Parameters Form, the Visual Analog Scale, the McGill Pain Questionnaire, the Piper Fatigue Scale, and the 5-D Itch Scale. Findings: It was determined that there was a statistically significant decrease in the pain, fatigue, and itching levels of the patients in favor of the intervention group in the second and third measurements (p < 0.05). Although there was no change in the pain and fatigue levels of the patients in the control group, the levels of itching increased statistically and significantly (p < 0.05). Discussion: The findings suggest that Reiki has an effect on pain, fatigue, and itching in hemodialysis patients. Trial Registration: ClinicalTrials.gov: NCT05531175
Optical and electronic properties of confined exciton in a dot-in-rod structure
This study explores the excitonic properties of CdSe/CdS dot-in-rod nanostructures using the perturbation method within the effective mass approximation, combined with the finite element method. We analyze the first three excitonic energy levels (1S, 2S, and 3S), along with the electron and hole states, the exciton binding energy, and absorption coefficient for transitions between these levels under an applied electric field, as functions of the dot radius (Rc) and sidewall thickness (C). Our results reveal that the exciton binding energy reaches a maximum at a critical dot radius (Rc≃2nm), while excitonic energy levels decrease with increasing R due to quantum confinement effects. The applied electric field significantly modifies the exciton energy, increasing the first and third states while decreasing the second due to the quantum-confined Stark effect, which induces carrier polarization. The absorption coefficient for transitions among the 1S, 2S, and 3S peaks in an energy range comparable to experimentally observed photoluminescence spectra. Additionally, as Rc increases, the absorption peak undergoes a blue shift, whereas an increase in C results in a redshift and a slight enhancement in amplitude. These findings highlight the potential for tuning excitonic properties in optoelectronic and quantum applications
TÜRKİYE’DE EĞİTİM POLİTİKALARI ALANINDA YAPILAN LİSANSÜSTÜ TEZLERİN BİBLİYOMETRİK ANALİZİ (2021–2025)
Bu araştırmada, 2021–2025 yılları arasında Türkiye’de eğitim politikaları alanında yazılmış lisansüstü tezlerin bibliyometrik açıdan analizi amaçlanmıştır. Çalışma, belirlenen anahtar kelimeler ve dahil etme kriterleri doğrultusunda Yükseköğretim Kurulu (YÖK) Ulusal Tez Merkezi verilerine dayalı olarak gerçekleştirilmiştir. İçerik açısından uygun bulunan 66 tez araştırmanın çalışma grubunu oluşturmuştur. Tezler; yıl, üniversite, tez türü, danışman unvanı, araştırma yöntemi, veri toplama aracı ve tematik içerik gibi değişkenler açısından incelenmiştir. Veriler, bibliyometrik analiz tekniğiyle sistematik biçimde çözümlenmiş; frekans ve yüzde dağılımları ile yorumlanmıştır. Bulgulara göre en fazla tez 2021 ve 2022 yıllarında yazılmış; tezlerin büyük çoğunluğu nitel yöntemle yapılandırılmış ve doküman analizi deseni tercih edilmiştir. Tematik olarak eğitim reformları, 2023 Eğitim Vizyonu ve yükseköğretim politikaları öne çıkarken; tezlerin büyük bir kısmı Doç. Dr. unvanlı danışmanlar tarafından yönetilmiştir. Çalışma, 2021 sonrası döneme ilişkin bibliyografik boşluğu doldurarak eğitim politikaları alanındaki akademik yönelimleri ortaya koymakta ve gelecek araştırmalar için yol gösterici bilgiler sunmaktadır.</p
A machine learning analysis of the impact of helideck surface conditions on helicopter safety
This study provides a comprehensive analysis of the impact of helideck surface conditions on the safe operation of helicopter landing and take-off platforms on offshore drilling vessels. Over time, the deterioration of helideck surface coatings necessitates periodic friction coefficient testing every two years in compliance with international standards. Surface coatings that fail to meet the required thresholds are replaced, and the performance of the renewed surface is reassessed using the Helideck Micro GripTester (HMGT), in accordance with U.K. Safety Regulation Group CAP 437 (2023) standards for offshore helicopter landing areas. The findings indicate that the renewed helideck surface coatings lead to a significant increase in the coefficient of friction, thereby enhancing the stability of helicopters upon landing and while on deck. Independent sample t-test and correlation analyses confirmed statistically significant differences between the old and new surface conditions, demonstrating the positive impact of surface improvements on coefficient of friction and, therefore, operational safety. Furthermore, machine learning techniques were employed to model and analyse the non-linear relationships between surface conditions and flow number. The model results demonstrate that variations in helideck surface coatings directly influence helicopter performance and operational safety. These findings underscore the critical importance of regular resurfacing and friction testing in ensuring the safety and reliability of offshore helicopter operations