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Eğitim Bilimleri Lisansüstü Öğrencilerinin Üretken Yapay Zekâ Kullanım Deneyimleri ve Etik İkilemleri Üzerine Fenomenolojik Bir Araştırma
No full textPANAMA KONFERANSI (1939): İKİNCİ DÜNYA SAVAŞI ÖNCESİ LATİN AMERİKA'NIN BÖLGESEL GÜVENLİK ARAYIŞI
No full textYangın Afetlerine Yönelik Farkındalık Ölçeğinin Geliştirilmesi ve Psikometrik Değerlendirilmesi
No full text
Polymyxin B-Associated Acute Kidney Injury: Risk Factors and Short-Term Outcomes in a Single-Center Retrospective Cohort
No full textNew hydrazone derivatives: synthesis, characterization, carbonic anhydrase I-II enzyme inhibition, anticancer activity and in silico studies
No full textA new series of hydrazone derivatives (1a-1l) were prepared from a condensation reaction between different hydrazide derivatives and 3-formylbenzoic acid. Through the use of several spectral techniques, such as 1H-NMR, 13C-NMR, and elemental analysis, the structures of the compounds were clarified. The crystal structure of compound 1d was obtained by single-crystal X-ray crystallography. They were found to have inhibitory effects on the anticancer potentials and human carbonic anhydrase isoforms I and II. Compound 1d was found to be the strongest inhibitor, with IC50 values of 0.133 μM against hCA I. Also, compound 1l showed the highest inhibitory activity with IC50 values of 3.244 μM against hCA II. Moreover, their cytotoxic effects on rat glioma cell and colon adeno carcinoma cell lines were evaluated. According to the cytotoxicity results, compounds 1j and 1l exhibited the highest cytotoxicity on the HT29 cell, while compounds 1e, 1g, and 1l showed the strongest cytotoxic effect on C6 cell line. Compound 1l, which carries the methoxy substituent at the 3rd position on the phenyl ring, was effective against both cancer cells and showed the highest inhibitory effect on hCA II. The ADME/T properties and molecular docking of the molecules with the highest activity were examined
Çok Boyutlu Algılanan Sosyal Destek Ölçeği’nin Muhasebe Meslek Mensuplarında Geçerlik, Güvenirlik ve Demografik Değişkenler Açısından İncelenmesi: Sivas İlinde Bir Araştırma
No full textMapping habitat suitability of the brown bear in Artvin-Şavşat region, Turkey
No full textWe aimed to build seasonal habitat suitability models and maps for brown bear (Ursus arctos), which are distributed in the Artvin-Şavşat region of northeastern Turkey. Between May 2018 and May 2020, 200 camera traps were deployed using an opportunistic camera-trap method. Over 280,000 images were captured during 121,140 camera-trap days, with images including 1,860 brown bears detected. Maximum Entropy analysis, which uses only presence data, was employed for seasonal habitat suitability modelling and mapping of brown bears using 30 independent variables and the presence data of brown bears in spring, summer, autumn, and winter. The difference between the training and test data sets of area under the curve (AUC) scores for each model was used to select the most supported model. The model for spring (AUC: 0.920-0.915) included land use class, annual mean temperature, elevation, annual precipitation, ruggedness, and slope class. The model for summer (AUC: 0.921-0.913) included road density, land use class, annual mean temperature, ruggedness, and slope class. Land use class, road density, distance to settlement, annual mean temperature, elevation, slope class, seasonal precipitation, and ruggedness contributed to the model for autumn (AUC: 0.928-0.925). Model results for different seasons were mapped and areas prioritized for protection of the endangered brown bear were determined
Tüketici Mutluluğu ve Tatmini Aynı Anlama mı Gelir? Satın Alma Niyeti Bu Denkleme Nasıl Uyar?
No full textTüketici davranışlarını anlamada mutluluk ve tatmin, özellikle dijitalleşmenin perakende satışlarda ve tüketici alışkanlıklarında yarattığı karmaşık dinamikler içinde giderek artan bir önem taşımaktadır. Bu anlayış, firmaların rekabet avantajı elde etmesinde kritik bir rol oynamaktadır. Bu çalışma, Bandura'nın Üçlü Determinizm Modeli'ni teorik bir çerçeve olarak kullanarak, dijital platformlardan yapılan alışverişlerde tüketici tatmini ile anlık ve uzun dönemli mutluluk arasındaki doğrusal olmayan ilişkileri ve bu etkileşimi satın alma niyetinin seviyelerine göre test etmeyi amaçlamaktadır. Toplam 429 katılımcıyla yürütülen çalışmada; tatmin ve mutluluk türleri arasındaki karmaşık yapı ve etkileşim, polinom modeller aracılığıyla incelenmiştir. Bu doğrusal olmayan modellerin basit doğrusal modellere göre uygunluğu istatistiksel olarak açıklanmıştır. Araştırma sonucunda, tüketici tatmini ile hem anlık mutluluk hem de esenlik (uzun dönemli mutluluk) arasındaki ilişkinin doğrusal olmadığına dair temel hipotezler desteklenmiştir. Bu doğrusal olmayan etkileşimlerin, tüketicilerin mevcut tatmin ve mutluluk düzeylerine göre tanımlanan farklı segmentlerde değişkenlik gösterdiği ortaya konmuştur. Çalışmayla özellikle dijital tüketiciler üzerine yazılmış olan mevcut literatüre doğrusal olmayan çözüm bakış açısının kazandırıldığı düşünülmektedir. Elde edilen bulgular, tüketici tatmini ve mutluluğu arasındaki doğrusal olmayan etkileşimin, pazarlama stratejilerinin tüketicilerin farklı "tatmin-mutluluk" profillerine göre daha esnek, hedef odaklı ve segmente özel olması gerektiğini göstermektedir. İşletmelerin, bu doğrusal olmayan dinamikleri anlayarak müşteri deneyimini iyileştirmesi, uzun vadede müşteri bağlılığını artırma potansiyeli taşımaktadır.n understanding consumer behavior, happiness and satisfaction are increasingly essential elements, especially within the complex dynamics of digitalization in retail sales and consumer habits. This understanding plays a critical role in firms gaining a competitive advantage. This study, using Bandura's Triadic Determinism Model as a theoretical framework, aims to test the non-linear relationships between consumer satisfaction and immediate and long-term happiness in purchases made on digital platforms, and this interaction according to the levels of purchase intention. In the study conducted with a total of 429 participants, the complex structure and interaction between satisfaction and happiness types were examined through polynomial models. The appropriateness of these non-linear models compared to simple linear models was statistically explained. As a result of the research, the basic hypotheses suggesting that the relationship between consumer satisfaction and both immediate happiness and well-being (long-term happiness) is nonlinear were supported. These non-linear interactions were found to vary in different segments defined by consumers' current levels of satisfaction and happiness. This study is thought to contribute a non-linear solution perspective to existing literature, especially on digital consumers. The findings indicate that the non-linear interaction between consumer satisfaction and happiness necessitates that marketing strategies be more flexible, target-oriented, and segment-specific according to consumers' different "satisfaction-happiness" profiles. It is suggested that businesses understand these non-linear dynamics and thereby improve the customer experience have the potential to increase customer loyalty in the long term