IIUM Medical Journal Malaysia (IMJM)
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    1450 research outputs found

    Chronic Lactiferous Fistula: A Case Report

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    Lactiferous or milk fistula is a tract between the skin and lactiferous duct. Chronic lactiferous duct is uncommon and generally formed during lactating period. It commonly result from complication of the surgical intervention, such as excision biopsy of breast mass or incision and drainage (I&D) for breast abscess. We reported a case of chronic lactiferous fistula secondary to previous I&D for breast abscess in 31 year old lactating woman

    Evaluation Of Calcium And Phosphorus Content In Virgin Coconut Oil, Coconut Milk And Coconut Water Using ICPMS- Assessment Of Remineralization Potential For Tooth Enamel

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    Introduction: Dental decays happened due to demineralization of dental minerals because of oral acidic environment. The minerals that usually dissolved out from the enamel are calcium (Ca) and phosphorus (P). To ensure more Ca and P absorbed via remineralization, high Ca and P content in daily diet supply are required. In Malaysia, virgin coconut oil (VCO), coconut milk (CM) and coconut water (CW) are a few of many major diet component of daily diet. The aim for this study is to evaluate the Ca and P content of VCO, CM and CW. Materials and Methods: For these types of foods, Inductive Coupled Plasma-Mass Spectrometry (ICP-MS) is used in analyzing their Ca and P concentration. The samples undergone acid digestion (Method 3051a) using Teflon vessels under 150°C. Then, the samples were diluted and the readings are compared. Result:The VCO showed highest concentration of Ca (472.62 ppb) followed by CW (453.33 ppb) and CM (444.00 ppb). Whilst, CM showed the highest P concentration with 251.00 ppb and least P concentration from VCO (54.07 ppb). Comparing the concentration of the minerals altogether, although Ca concentration in CM is the least, it is still considered high. Conclusion(s): With supports of high concentration of P, CM displayed a promising potential of Ca and P supply to promote remineralization of enamel caries

    Mandibular Advancement By Distraction Osteogenesis For Obstructive Sleep Apnea In Patient With Pierre Robin Sequence: A Case Report

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    Introduction: Pierre Robin Sequence (PRS) is a condition consists of set of anomalies, which are cleft palate, micrognathia and glossoptopsis. Management of patients with PRS addresses two main problems, namely airway obstruction and feeding difficulties. Airway obstruction may lead to obstructive sleep apnea (OSA). Treatment modalities for OSA are based on the causes. There are surgical and non-surgical methods. Non-surgical methods such as diet, medication, oral appliances and continuous positive airway pressure (CPAP) can only be employed in moderate cases. Surgical method such as maxillo-mandibular advancement or expansion can be achieved by orthognathic surgery or distraction osteogenesis. We present a case report of successful management of airway in a 23-year old lady who has a PRS features with severe OSA. In our case, the respiratory obstruction that was caused by retrognathic and hypoplastic mandible has been corrected successfully with distraction osteogenesis and the OSA was found to be improved tremendously

    Primary Causes for Tooth Extraction Among Patients Attending The IIUM Kulliyyah Of Dentistry Polyclinic

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    Introduction: To investigate the pattern and major causes of tooth extraction among patients attending IIUM Kulliyyah of Dentistry Polyclinic. Materials and Methods: This is a retrospective study. Total 1036 number of tooth extraction done in the polyclinic were recorded to determine the causes of tooth extraction among patients attending the Polyclinic IIUM. Study period was from year 2012 to 2015. Collecting patients’ information was required from Pearl dental system and clinical year students’ Oral Surgery Department logbooks. Information includes patient’s name, identity card number, diagnosis and indications for dental extractions noted for each case. Other demographic features such as age, gender and race were analysed by using SPSS Chi-Square test. Result: The major causes of tooth extraction were dental caries 53.3%, periodontal problem 20.9%, impaction 7.7%, orthodontic reason 4.6%, malposted 3.6%, pre-prosthetic 0.9% and other reasons 8.9%. Among races, Malay had highest tooth extraction cases which were 85.2%, followed by Chinese 11.2%, Indian 2.8% and others 0.8%. Based on gender, female had total of 56.6% of tooth extraction while male 43.4%. Highest prevalence of extraction was patients’ age between 21 to 40 years old (44.4%) followed by age between 41 to 60 years old (35.5%). Conclusion: Dental caries is the major causes for tooth extraction among patients attending IIUM Kulliyyah of Dentistry Polyclinic

    The Levels of Depression, Anxiety and Stress on Pre and Post Knee Arthroplasty Patients

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    Introduction: Total knee arthroplasty represents a major advance in the treatment of degenerative joint disease. It provides excellent restoration of joint function and pain relief. The primary indication for total knee arthroplasty is to relieve pain caused by severe arthritis, with or without significant deformity. This study is to assess psychological impact pre and post arthroplasty. Materials and method: A prospective study on a cohort of patients from June 2010 untill December 2011 admitted to Hospital Tengku Ampuan Afzan for total knee replacement. Cognition tested using DASS21 (Depression Anxiety Stress Scales 21). Questionnaires were distributed 2 days before the operation and 6 months after the operation during clinic follow up. Verbal consent acquired from the patients before giving the questionnaires. Sets of questions are self-administered. Results: As for DASS 21 analysis, pre and post-operative depression was 19.91±4.92 and 6.42±3.64 respectively. Moderate depression became normal post-operative. Questions regarding positive feeling, courage to do things, hope, self- appreciation and the meaning of life were asked pre and post operatively. Pre-operative anxiety was 19.49±4.92 and post-operative anxieties at 6 months were 6.42±3.64. Severe anxiety became normal after 6 months. Patients were asked about mouth dryness, difficulty in breathing on resting, tremor, panicking and unnecessary anxiety pre and post operatively. Post-operative stress improved tremendously from 22.47±4.27 down to 8.56±3.42. Conclusion: As a conclusion, total knee arthroplasty is well accepted in Malaysia. It improves patients’ social and emotional well-being. With the current advancement in total knee arthroplasty, surgeons not only looking into the post-operative physical function, they also look after the cognitive function as the outcome measure of total knee arthroplasty

    The Dimensions of Auditory Hallucination in Schizophrenia: Association with Depressive Symptoms and Quality of Life

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    Introduction: Auditory hallucination (AH) is often unexplored in depth in clinical practice. This study sought to ascertain the relationship between AH, depressive symptoms and quality of life (QOL) and its association with socio-demographic and clinical variables. Methods: This was a cross sectional study done in a psychiatry unit involving 60 schizophrenic patients between 18 to 60 years old. Psychotic Symptom Rating Scale – Auditory Hallucination subscale (PSYRATS-AH), Calgary Depression Scale for Schizophrenia (CDSS) and World Health Organization Quality of Life-Brief scale (WHOQOL-BREF) were used as instruments. Results: Alcohol intake was found to be significantly associated with the severity of AH. A significant moderate positive correlation was found between AH total score and CDSS (r=0.53, p<0.001) and moderately high correlation between emotional characteristics subscale with CDSS (r=0.651, p<0.005). The PSYRATS-AH dimensions; amount of distress (r=0.721, p<0.001) and intensity of distress (r=0.757, p<0.001) showed significant high correlation with CDSS. As for QOL, frequency of AH (r=-0.419, p<0.01) and CDSS (r=0.435, p<0.01) showed significant moderate negative correlation, while duration, loudness, amount and intensity of distress, disruption to life and controllability of voices had significant fair correlation with QOL. Multiple regression analysis revealed that the frequency of AH (p=0.047), controllability of AH (p=0.027) and depressive symptoms (p=0.001) significantly predict QOL. Conclusion: Our results demonstrated that each dimension of AH had different contributions towards depressive symptoms and the QOL in patients with schizophrenia. Therefore, appropriate treatment focusing on the specific dimension of AH not only may reduce depressive symptoms, but may also improve QOL of these patients

    Effect of Flaxseed Extract on the Liver Histological Structure in Streptozotocin Induced Diabetic Rats

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    Introduction: Diabetes mellitus has become a serious warning to mankind health all over the world. The management goal of diabetes is to keep blood glucose levels as close as possible to healthy individuals. Medications used to treat diabetes are usually associated with complications and may cause different side effects. Many traditional anti-diabetic plants have become popular in the management of diabetes mellitus. Flaxseed has been used as traditional medicine for centuries. Objective: This study aimed to evaluate the hepatoprotective effects of flaxseed extract in streptozotocin (STZ)-induced diabetic rats. Methods: Diabetes mellitus was induced in Sprague-Dawley rats using a single injection of streptozotocin (60 mg/kg i.p.). The rats were divided into five groups of 8 rats each. Group NC, normal control rats; Group NF, normal rats treated with flaxseed extract (400 mg/kg); Group DC, diabetic control rats; Group DG, diabetic rats treated with glibenclamide (0.6 mg/kg); Group DF, diabetic rats treated with flaxseed extract (400 mg/kg); for 4 weeks. Results: There were significant increase in relative liver weight, blood glucose levels in DC group comparing to NC group (p<0.05). The disturbance of these parameters was ameliorated in DF and DG groups. Histological observation revealed congestion of central veins, degeneration of hepatocytes, and reduced glycogen granules in DC group. These pathological changes were ameliorated in the flaxseed extract and glibenclamide treated rats. Conclusion: Flaxseed extract may represent a candidate alternative treatment to control diabetes mellitus and its related hepatopathy

    Clinical Quiz: The Strawberry Coloured Breastmilk

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    Barriers To Utilization Of Oral Health Care Services Among Antenatal Mothers In Kuantan, Pahang

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    Introduction: During pregnancy, increased acidity in the mouth increases the risk of antenatal mother to get dental caries. It is worsen if antenatal mother has morning sickness like vomiting during pregnancy. It can aggravate the problem by exposing the teeth to more gastric acid. In addition, antenatal mothers have hormonal changes that they are more susceptible to periodontal problems. Therefore, it is important for antenatal mother to get dental treatment and use oral health service. This study aim is to describe barriers to utilisation of oral health care services among antenatal mothers attending the Klinik Kesihatan Ibu dan Anak around Kuantan. Materials and Methods: A cross sectional study which was conducted among purposely selected 296 antenatal mothers aged 18-45 years from Kuantan, Pahang in 18 months duration. Study used validated selfadministered questionnaire to obtain information on the variables of interest. Results: Common barriers to utilization of services among antenatal mothers are fear to dental pain (45.6%), time constraints- busy at workplace (36.5%) and feeling of not having any dental problems (36.1%). Meanwhile the least barrier to oral health care services among antenatal mothers is attitude of the dentist (0.7%), followed by attitude of the staff (1.4%) and condition of treatment room (1.7%) Conclusion(s): Fear of dental pain is the main barrier to utilization of service among antenatal mothers and dissatisfaction of the service provided is the least barrier among other factors

    Improving Bond Strength And Thermal Behaviour Of New Sodalite Infiltrate Ceramic Core Materials

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    Introduction: The mismatch in coefficient of thermal expansion (CTE) between the veneered porcelain and the ceramic core has been primarily identified as the cause of core/veneer chipping in all-ceramic restorations. This study aimed to evaluate the effect of sodalite infiltration on the CTE behaviour and bond strength of different all-ceramic prostheses. Materials and Methods: The experimental groups were synthesised sodalite-infiltrated alumina (IA-SOD) and synthesised sodalite-infiltrated zirconia-toughened alumina (ZTA) (IZ-SOD), while the control groups were glassinfiltrated alumina (IA-glass) and glass-infiltrated ZTA (IZ-glass). Forty cylindrical-shaped samples (5mm diameter; 10mm height) were tested for CTE. Another forty disc-shaped samples (12mm diameter; 1.2±0.2mm thick) and veneered with cylinder-shaped low-fusing porcelain (2mm high; 2mm diameter) were prepared for shear bond strength test. SEM, stereo microscope and AFM were used to investigate the structural characteristics of samples at the fracture surface. Results: The CTE values for both IZ-SOD and IA-SOD were 8.62 x 10-6 K-1 and 8.37 x 10-6 K-1 respectively, which were statistically higher than IZ-glass and IA-glass (8.08 x 10-6 K-1 and 7.63 x 10-6 K-1 , respectively) (p0.05). Conclusion(s): The higher CTE mismatch and bond strength of the newly developed SOD-infiltrated samples than did the commercial glassinfiltrated samples could thus make them suitable for all-ceramic dental prostheses

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