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The protective effect of curcumin on the diabetic uterus: Quantitative and qualitative evaluation
No full textThe objective of this study was to examine the impact of diabetes on the rat uterus and to assess the potential therapeutic benefits of curcumin in a diabetic uterus.A total of thirty-eight female Wistar albino rats were randomly assigned to seven experimental groups. The control group (Cont) was not subjected to any treatment. The sham group (Sham) was administered corn oil, while the curcumin group (Curc) received 30 mg/kg curcumin. A single dose of 50 mg/kg streptozotocin (STZ) was administered to induce experimental diabetes. The diabetic animals were then divided into four groups: a group with diabetes mellitus (DM), a group administered curcumin after seven days of diabetes induced (DC1) and 21 days (DC2) after the onset of diabetes, and a group that received curcumin simultaneously with STZ (DC3). The Cavalieri's method was used to estimate the volume ratios of the uterine epithelium, layers, and blood vessels.The volume ratio of the myometrium was observed to be higher in the DC2 group than in the Cont and DM groups. Conversely, the endometrial volume ratio was found to be lower in the DC2 group than in the Cont group. The cell borders and basement membranes of the epithelial and gland cells were well preserved in the curcumin treatment groups, despite the obvious damage observed in the DM group. Similar findings were also observed in the electron microscopic sections, with collagen fibers, which were arranged in thick bands in the DM group and were unable to maintain their ultrastructure, were well organized in the DC1, DC2, and DC3.Considering that it improves the endometrial structure and reduces degeneration in the surface and gland epithelium, it can be said that curcumin is an effective agent in reducing and preventing complications associated with DM in the uterus.https://doi.org/10.1016/j.tice.2025.102852https://pubmed.ncbi.nlm.nih.gov/4006827
Assessment Of Radıological Health Risk Caused Bynatural Radioactıvıty In Bottled Sprıng Water Consumedin Türkıye
No full textİçme suyunun kalitesi, fiziksel, kimyasal, mikrobiyal ve radyolojik yönleriyle insan sağlığı açısından büyük önem taşımakta ve musluk veya ambalajlı su tercihlerinde önemli rol oynamaktadır. Türkiye'de tüketilen ambalajlı doğal kaynak suyunun ana kaynağını, sondaj kuyuları ile akiferlerden elde edilen yer altı suları oluşturmaktadır. Bu suların radyolojik kalitesi, akifer kayaçlarından gelen suda çözünmüş doğal radyonüklitlerin derişimi ile belirlenmektedir. Bu çalışma, Türkiye'de ticari olarak satılan ambalajlı doğal kaynak suyu markalarına ilişkin ilk ayrıntılı radyolojik verileri sunmaktadır. Seksen iki ambalajlı doğal kaynak suyu markasının içerdiği radyolojik olarak önemli radyum izotoplarının (226Ra ve 228Ra) ve potasyum (40K) radyoizotopunun aktivite derişimleri, bir gama ışını spektroskopisi ile ölçüldü. İncelenen ambalajlı doğal kaynak suyu örneklerinin tüketilmesinin neden olduğu radyolojik risk, yetişkinler için yıllık etkin radyasyon dozu ve buna karşılık gelen yaşam boyu kanser riski tahmin edilerek değerlendirildi. Su örneklerinde ölçülen 228Ra'nın aktivite derişimleri, Dünya Sağlık Örgütü tarafından tavsiye edilen 0,1 Bq/L'lik kılavuz düzeyin üzerinde ve 226Ra'nın aktivite derişimleri ise 1 Bq/L'lik kılavuz düzeyin altında bulundu. Bununla birlikte, radyolojik risk değerlendirmesi, Türkiye'de yıllık olarak 130 L ambalajlı doğal kaynak suyu tüketilmesinin, insan sağlığı için önemli bir risk oluşturmadığını ortaya koymaktadır
Exploring vestibular dysfunction in primary hypothyroidism using cervical vestibular evoked myogenic potentials
No full textPurpose: This research was conducted to assess cervical vestibular evoked myogenic potential (cVEMP) test responses in patients with primary hypothyroidism without vestibular symptoms. Materials and Methods: Thirty-one patients diagnosed with primary hypothyroidism and who had not yet started on hormone replacement therapy, together with a 26-member control group, were enrolled in the research. All participants underwent detailed otorhinolaryngological examinations and thyroid function, cVEMP, and audiological tests. cVEMP records were compared between the groups. Results: Thirty-one patients aged between 21 and 57 years (38.5±9.7) and a control group of 26 healthy volunteers aged between 20 and 52 years (36.1±8.8) were included in the study. Absent VEMP responses were observed in 12 members of the patient group and in three of the control group. Interpeak amplitudes (IPAs) in both ears were significantly lower in the patient group than in the controls. While no significant difference was found between the groups’ VEMP threshold values, asymmetry rates in both ears were significantly higher in the patient group. Conclusion: cVEMP can be usefully employed in the detection of subclinicalhttps://doi.org/10.17826/cumj.155096
A Theoretical Evaluation of Smart Production Systems and Industrial Robots within the Context of Industry 4.0
No full textThis study comprehensively addresses the role of intelligent manufacturing systems, industrial robots, and dark factories in production processes and the transformation process brought about by Industry 4.0. Today, manufacturers are pressured to produce higher-quality products with shorter lead times. This requirement has necessitated that production systems become integrated, automated, and intelligent. Smart manufacturing creates flexible, responsive and highly efficient production environments using artificial intelligence (AI), internet of things, big data analytics and robotics. Industrial robots have become systems that can not only act on a task basis but also learn, predict, and actively participate in production processes by interacting with humans. In this direction, dark factories are facilities that can produce 24 hours a day without human intervention and offer significant advantages regarding occupational safety, quality and efficiency. However, there are difficulties in the widespread use of these systems, such as high investment costs, applicability limitations in some sectors and the decreasing need for unskilled labour. In conclusion, for the technological opportunities offered by Industry 4.0 to provide sustainable and inclusive benefits, investments incompetent human resources should be increased, education policies should be restructured, and strategic public support should be activated.https://dx.doi.org/10.5281/zenodo.15777971https://dx.doi.org/10.5281/zenodo.15777970https://dx.doi.org/10.5281/zenodo.1579024
An investigation of social studies teachers' self-efficacy in political literacy education
No full textPolitik okuryazarlık, demokratik toplumların sürdürülebilirliği ve bireylerin etkin yurttaşlık rolleri üstlenebilmeleri açısından merkezi bir öneme sahiptir. Bireylerin politik okuryazarlık yeterliklerinin geliştirilmesi amacıyla eğitim ortamlarında sistematik ve yapılandırılmış uygulamalara ihtiyaç duyulmaktadır. Bu bağlamda okullar, öğrencilerin politik okuryazarlık becerilerini kazanabilecekleri, eleştirel ve katılımcı bir öğrenme ortamı sunacak şekilde kurgulanmalı; öğretmenler ise pedagojik yeterlikleri doğrultusunda bu sürece yön vererek öğrencilerin teorik bilgilerini pratikle ilişkilendirmelerine katkı sağlamalıdır. Bu araştırmanın amacı, sosyal bilgiler öğretmenlerinin politik okuryazarlık eğitimi özyeterlik düzeylerini belirlemek ve bu düzeylerin çeşitli demografik ve mesleki değişkenler bağlamında farklılaşıp farklılaşmadığını incelemektir. Çalışma, tarama modeli kapsamında desenlenmiş olup araştırmanın örneklemini 2022-2023 eğitim-öğretim yılında Türkiye genelinde görev yapmakta olan 690 sosyal bilgiler öğretmeni oluşturmaktadır. Veri toplama aracı olarak araştırmacı tarafından geliştirilen “Sosyal Bilgiler Öğretmenlerinin Politik Okuryazarlık Eğitimi Özyeterlik Ölçeği” kullanılmıştır. Araştırmanın nicel verileri bağımsız örneklem t testi ve tek yönlü varyans analizi (ANOVA) teknikleriyle değerlendirilmiştir. Elde edilen bulgular, öğretmenlerin genel olarak yüksek düzeyde politik okuryazarlık eğitimi özyeterliğine sahip olduklarını ve cinsiyet, siyaset bilimine ilişkin ders alma, Türkiye’yi ilgilendiren politik konuları konuşma sıklığı, uluslararası politik konuları konuşma sıklığı durumları gibi bazı değişkenler açısından anlamlı farklılıklar gösterdiğini ortaya koymuştur. Araştırma sonuçları, öğretmenlerin politik okuryazarlık eğitimi konusundaki özyeterlik algılarının öğrencilerin demokratik bilinç ve siyasal katılım becerilerinin gelişiminde belirleyici bir unsur olduğunu göstermektedir. Çalışmadan elde edilen bulgular doğrultusunda, öğretmen yetiştirme programlarında politik okuryazarlık odaklı içeriklerin güçlendirilmesi ve öğretmenlerin mesleki gelişim süreçlerinde bu yeterliklerin desteklenmesine yönelik uygulamalara yer verilmesi önerilmektedir. Ayrıca, daha geniş örneklem gruplarında gerçekleştirilecek benzer araştırmalar, bulguların genellenebilirliğini artırma açısından önem arz etmektedir
A multilevel analysis of green organizational support among hotel employees in Türkiye
No full textThis study tests the cross-level association between green organizational support (GOS) among team members, green team resilience (GTR), green work engagement (GWE), and pro-environmental behaviour (PEB). Data for this study came from 59 work groups and 372 individuals working in 14 hotels in Antalya, Türkiye. To account for the nested data structure, hierarchical linear modeling was employed using R programming language. The present research reveals that GOS directly and indirectly correlates with GTR, GWE, and PEB. In addition, GOS promotes GTR and fosters GWE and PEB. The authors infer that eco-friendly support provided by the organization to the hotel employees can facilitate the green resilience of teams and boost employees' GWE, consequently increasing individual-level PEB. Practitioners can utilize these insights to implement effective strategies that support environmental initiatives, improve team dynamics, and engage employees in sustainability efforts, thereby contributing to the overall environmental performance of hotels.https://doi.org/10.54055/ejtr.v39i.363
Immature ganulocytes are a potential biomarker in the early diagnosis of lower extremity subacute arterial thrombosis
No full textAims: Acute arterial embolism in peripheral arteries is generally diagnosed quickly. In contrast, subacute arterial thrombosis (SAT), which arises as an acute exacerbation of chronic peripheral artery disease (PAD), is often more challenging to diagnose rapidly, primarily due to the development of collateral circulation. This study aims to investigate the role of immature granulocytes (IG) in the early diagnosis of SAT in patients with chronic PAD. Methods: This retrospective study was conducted at a single center between 2019 and 2021. A total of 99 patients with chronic lower extremity PAD were included in the study. Of these, 27 patients (27.2%) who developed exacerbations in the form of SAT were assigned to the SAT group. The remaining 72 patients (72.8%) with chronic PAD were included in the control group. Blood samples from patients in both groups were collected at their first admission before receiving any treatment. Complete blood count parameters were analyzed using an automatic hematological analyzer and compared between the two groups. Results: Comparison between the control and SAT groups revealed significant differences in hemogram parameters. These parameters included white blood cell count (WBC, phttps://doi.org/10.32322/jhsm.1631350https://dergipark.org.tr/tr/pub/jhsm/issue/92158/163135
WEB SİTE KALİTESİ, MEMNUNİYET VE GÜVENİN SATIN ALMA NİYETİ ÜZERİNDEKİ ETKSİ
No full textOnline alışveriş yapan Azerbaycanlı tüketiciler ekseninde gerçekleştirilen bu araştırmada web site kalitesi, memnuniyet ve güven değişkenlerinin satın alma niyeti üzerindeki etkileri ile web site tasarımının memnuniyet ve güven değişkenleri üzerindeki etkisi belirlenmeye çalışılmıştır. Araştırma amacı doğrultusunda 05.04.2024-08.06.2024 tarihleri arasında Azerbaycanlı tüketiciler arasından kolayda örnekleme yöntemi ile ulaşılan 508 bireye ulaşılarak anket uygulaması gerçekleştirilmiştir. Bu kapsamda toplanan veriler SPSS ve AMOS programları ile analiz edilmiştir. Web site kalitesi, memnuniyet, güven ve satın alma niyeti değişkenleri arasındaki ilişkiler yapısal eşitlik modellemesi ile analiz edilmiştir. Yapılan analiz sonucunda web site kalitesinin güven ve memnuniyeti etkilediği, ancak satın alma niyeti üzerinde anlamlı etkiye sahip olmadığı, güven ve memnuniyetin ise satın alma niyeti üzerinde anlamlı etkiye sahip olduğu saptanmıştır.https://doi.org/10.57085/ufebud.161004
Effect of fire intensity on the earlier post-fire succession in Pinus nigra Arnold stands of Taşköprü, Kastamonu
No full textThis study investigates the post-fire vegetation development in black pine (Pinus nigra) stands, which are widely distributed in Kastamonu and are under threat from forest fires. To this end, sampling was conducted in 2017 in the Taşköprü and Bayam Forest Management Directorates, where fires occurred in 2003 and 2012. Sample plots (25 × 50 m) were established using the minimum area method in two regions affected by surface fires (low intensity) and crown fires (high intensity). To observe the temporal effects of high-intensity fire, a sample area from a 2003 fire site was also analyzed and compared using the Shannon diversity index and the Chi-square test. Results showed significant differences in the family Pinaceae and the life form cryptophyte. Although black pine was observed to remain the dominant species after the surface fire, one- and two-year-old species belonging to the Rosaceae and Fabaceae families were recorded during the early stage of vegetation. In areas with reduced canopy closure, species such as Cistus laurifolius, C. creticus, and Rubus sp. were observed. Species composition in the crown fire site closely resembled that of surface fire areas with broken canopy. Cistus laurifolius was the dominant species in crown fire areas, and the highest species diversity was found in the 2003 crown fire site.https://doi.org/10.17568/ogmoad.172764
School library projects in Türkiye: A critical view
No full textSchool libraries are an essential component of education and an indispensable tool in students’ individual, cultural, and social development. In Türkiye, especially with the establishment of the republic, the reforms carried out throughout the country have impacted the development of school libraries, but school libraries have faced many problems. Since 2011, school library projects, mainly led by the Ministry of National Education, have aimed to bring school libraries up to date, but the success of these projects has been controversial. This research critically analyzes the historical context and current state of school libraries in Türkiye through a literature review and evaluation of these projects. Feedback from educators and students underscores the need for improved library spaces and professional development in librarianship. The findings emphasize the necessity for substantial governmental support and the modernization of library facilities to foster a more effective educational environment.https://doi.org/10.1177/0340035225134251